scholarly journals Clinical Significance of the Pre-Atrial Electrical Activity Recorded by the Catheter Electrode in High Right Atrium : Symposium on Sinus Node Function and Its Abnormality

1980 ◽  
Vol 44 (7) ◽  
pp. 561-565
Author(s):  
SAICHI HOSODA ◽  
TADATAKA TOMITA
Keyword(s):  
Electrical Activity ◽  
Clinical Significance ◽  
Right Atrium ◽  
Sinus Node

scholarly journals Dual-Chamber Pacemaker After Sinus Node Dysfunction and Enlarged Right Atrium

Circulation ◽  
2021 ◽  
Vol 143 (17) ◽  
pp. 1725-1728
Author(s):  
Emilio Arbas-Redondo ◽  
Álvaro Montes-Muñiz ◽  
Carlos A. Álvarez-Ortega
Keyword(s):  
Right Atrium ◽  
Sinus Node ◽  
Sinus Node Dysfunction ◽  
Dual Chamber ◽  
Dual Chamber Pacemaker

Anatomy and physiology of the sinus node

ESC CardioMed ◽  
2018 ◽  
pp. 1940-1943
Author(s):  
Antonio Zaza
Keyword(s):  
Electrical Activity ◽  
Temporal Variability ◽  
Sinoatrial Node ◽  
Sinus Node ◽  
Membrane Current ◽  
Membrane Channels ◽  
Autonomic Balance ◽  
Electrical Excitation ◽  
Anatomy And Physiology ◽  
Mammalian Heart

The sinoatrial node (SAN) is the dominant pacemaker structure in the mammalian heart. It is endowed with robust intrinsic automaticity, providing periodic electrical excitation with a cycle widely modulated by autonomic influences. A number of membrane channels and transporters contribute to the net membrane current supporting SAN electrical activity, whose periodicity is determined by the interplay of two oscillators termed ‘membrane’ and ‘calcium’ clock respectively. This chapter describes the structure of the SAN, the peculiarities of its electrical cycle, the nature and modulation of the underlying clocks, and SAN interaction with atrial muscle. Moreover, the features and determinants of the temporal variability of the pacemaker cycle, clinically used to assess autonomic balance, are briefly discussed.

scholarly journals The arterial supply to the right atrium and the sinus node in classic tricuspid atresia

1988 ◽  
Vol 96 (5) ◽  
pp. 816-822 ◽  
Author(s):  
Sergio A. Battistessa ◽  
Siew Yen Ho ◽  
Robert H. Anderson ◽  
Audrey Smith ◽  
Philip B. Deverall
Keyword(s):  
Right Atrium ◽  
Sinus Node ◽  
Tricuspid Atresia ◽  
Arterial Supply ◽  
The Right

Cardiac Glycosides and Pacemaker Activity of the Sinus Node — A Microelectrode Study on the Isolated Right Atrium of the Rabbit

1978 ◽  
pp. 258-269 ◽  
Author(s):  
Gerhard Steinbeck ◽  
Felix I.M. Bonke ◽  
Maurits A. Allessie ◽  
Wim J.E.P. Lammers
Keyword(s):  
Right Atrium ◽  
Cardiac Glycosides ◽  
Sinus Node ◽  
Pacemaker Activity

Calcitonin gene-related peptide as potential neurotransmitter in guinea pig right atrium

1986 ◽  
Vol 250 (4) ◽  
pp. H693-H698 ◽  
Author(s):  
A. Saito ◽  
S. Kimura ◽  
K. Goto
Keyword(s):  
Guinea Pig ◽  
Right Atrium ◽  
Sinus Node ◽  
Calcitonin Gene Related Peptide ◽  
Dependent Manner ◽  
Chronotropic Response ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
The Right

The potential neurotransmitter role of calcitonin gene-related peptide (CGRP) in cardioacceleratory nonadrenergic noncholinergic (NANC) nerves was examined in the guinea pig right atrium in vitro. In the presence of atropine, a muscarinic antagonist, and atenolol, a beta-adrenoceptor antagonist, transmural nerve stimulation (TNS) of the isolated right atrium caused a positive chronotropic response, which is slow in both onset and decay. This TNS-induced slow response was assumed to be mediated by NANC nerves in the right atrium since tetrodotoxin inhibited the response. Dense distribution of CGRP-like immunoreactive (CGRP-I) nerves was demonstrated in the sinus node. Exogenously applied CGRP exerted a positive chronotropic effect on the isolated right atrium in a dose-dependent manner. Both CGRP-I nerves and NANC response induced by TNS were not affected by surgical sympathectomy and reserpine pretreatment but were abolished by the pretreatment of animals with capsaicin. The results suggest that CGRP is the neurotransmitter of cardioacceleratory NANC nerves in the right atrium of the guinea pig.

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