The Influence of Various Organ-Extracts upon the Circulatory System : The Fourth Report. The Influence of Parotid Gland Extract upon the Blood Pressure and the Pulse of Rabbits

1937 ◽  
Vol 3 (6) ◽  
pp. 241-244
Author(s):  
Takamasa Fukazawa
Keyword(s):  
Blood Pressure ◽  
Parotid Gland ◽  
Circulatory System ◽  
Gland Extract ◽  
Fourth Report

HUBUNGAN INTENSITAS KEBISINGAN DENGAN TEKANAN DARAH PADA PEKERJA AREA WORKSHOP

2020 ◽  
Vol 9 (1) ◽  
pp. 18-26
Author(s):  
Mariman Tjendera ◽  
Isramilda Isramilda
Keyword(s):  
Blood Pressure ◽  
Noise Intensity ◽  
Circulatory System ◽  
Sampling Technique ◽  
Strong Relationship ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Stage 1

Noise in the workplace is often a separate problem for the workforce so that it can cause mental-emotional disturbance as well as the heart and circulatory system. According to the 2013 Basic Health Research, the prevalence of high blood pressure in Indonesia at the age of ≥18 years is 25.8%. So the researchers wanted to find a relationship between noise intensity and blood pressure. This research method was observational analytic with a cross-sectional approach conducted at PT. Bintang Intipersada Shipyard, Batam City. The sampling technique was a total sampling with a population of 100 workers in 2018 and obtained results of 61 workers determined by inclusion and exclusion criteria. The results of the study were analyzed with a frequency distribution tabulated and tested with the Pearson Product Moment Test. The results of this study worker who were exposed to noise intensity ≤85 dBA had a normal blood pressure of 8 (36.5%) people, in workers who were exposed to noise intensity ≤85 dBA had blood pressure with Pre-hypertension as many as 12 (54.5% ) people, for workers exposed to noise intensity ≤85 dBA have 1 (4.5%) blood pressure with Stage 1 Hypertension, workers who are exposed to noise intensity ≤85 dBA have blood pressure with Stage 2 Hypertension as much as 1 (4.5 %) person. While workers who are exposed to noise intensity> 85 dBA have normal blood pressure of 0 (0%) people, workers who are exposed to noise intensity> 85 dBA have blood pressure with Pre-hypertension as much as 2 (5.1%) people, workers are exposed to noise intensity> 85 dBA had blood pressure with Stage 1 Hypertension as many as 14 (35.9%) people, then workers exposed to noise intensity> 85 dBA had blood pressure with Stage 2 Hypertension as many as 23 (59%) workers. The results of the Pearson Product Moment analysis value of p = 0,000 <α 0.05, there is a relationship between noise intensity and blood pressure with the magnitude of the correlation coefficient (r) which is 0.795 meaning, there is a strong relationship. Based on this study it can be concluded that there is a significant relationship between noise intensity and blood pressure.

scholarly journals The Relationship of Lifestyle with Hypertension Incidence in Antang Public Health Center of Makassar City

2020 ◽  
Vol 2020 ◽  
Author(s):  
Agussalim
Keyword(s):  
Public Health ◽  
Blood Pressure ◽  
Health Center ◽  
Health Workers ◽  
Circulatory System ◽  
Simple Random Sampling ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
Public Health Center ◽  
The Relationship

Hypertension is a disease that usually occurs in the circulatory system which can cause an increase in blood pressure above the normal value, which exceeds 140/90 mmHg. The intention of this study aims to understand the relationship between lifestyle and the incidence of hypertension in Antang Makassar Public Health Center in 2018. This research method uses quantitative analytic motives using a cross sectional approach with a population of 46 people and a sample of 36 respondents. This research was conducted on July 14-16 June. The method used is simple random sampling and the tool used to obtain data is a questionnaire. The scale used is Liker and Guttmann scale with univariate, bivariate analysis and chi-square test with significant a = 0, 05. The results of this study indicate there is a relationship between lifestyle and the incidence of hypertension in the Makassar Antang Health Center with P = 0, 01 smaller than the value of a = 0.05. Suggestions are for hypertensive patients, namely the need to check their health routinely to health workers in order to know the development of blood pressure and obtain information from health workers.

scholarly journals MAIN INDIVIDUAL AND TYPOLOGICAL PARAMETERS OF HIGHER NERVOUS ACTIVITY IN YOUNG PEOPLE OF DIFFERENT SOMATOTYPE WITH NORMAL AND HIGH BLOOD PRESSURE

2020 ◽  
Vol 5 (2) ◽  
pp. 47-55
Author(s):  
S. N. Vadzyuk ◽  
L. I. Horban ◽  
I. Ya. Papinko
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Nervous Activity ◽  
Circulatory System ◽  
Optimal Level ◽  
Functional Mobility ◽  
Control Group ◽  
Higher Nervous Activity ◽  
The Central Nervous System ◽  
The Individual

Background. The individual and typological features of the central nervous system are interpreted as highly genetically determined. Each somatotype is characterized by morphofunctional features of the activity of different systems, including the circulatory system. Objective. The aim of the research was to study the features of the main individual and typological parameters of higher nervous activity in persons of different somatotype with normal and high blood pressure (BP). Methods. In the control group of the surveyed patients the BP value corresponded to the optimal level according to the WHO classification (125 people). The second group consisted of individuals, whose systolic blood pressure exceeded 130 mmHg at the time of the study and (or) diastolic – 85 mmHg (135 people). Somatotyping technique by Carter and Heath was used. Functional mobility (FMNP) and strength of nervous processes (SNP) were determined using the Diagnost-1 program (Makarenko and Lizogub). Results. In the individuals with predominance of ecto- and mesomorphic somatotype component, higher levels of major nervous processes were reported in response to strenuous processing of information, which was associated with more advanced mechanisms of information processing, its neurophysiological support. In people with endomorphic somatotype the lower levels of FMNP and SNP were clearly detected that could indicate that the speed characteristics of the nervous processes in them are at a lower level. Conclusions. In normal blood pressure, the highest indicator of FMNP was found in the individuals with predominance of ecto- and mesomorphic component. In the group with high blood pressure, the indicator at the level below the average was in endomorphs. Predominance of the ectomorphic component tended to increase in the surveyed, and in the mesomorphs was at the average level. The lowest level of SNP was found in the individuals with endomorphic somatotype of both groups.

Indole-3-propionic acid, a tryptophan-derived bacterial metabolite, increases blood pressure via cardiac and vascular mechanisms in rats

2021 ◽  
Author(s):  
Piotr Konopelski ◽  
Dawid Chabowski ◽  
Marta Aleksandrowicz ◽  
Ewa Kozniewska ◽  
Piotr Podsadni ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Propionic Acid ◽  
Metabolic Activity ◽  
Ex Vivo ◽  
Circulatory System ◽  
Cardiovascular Responses ◽  
Gut Bacteria ◽  
Qtc Interval ◽  
Resistance Arteries ◽  
Wistar Kyoto

Objectives. Recent evidence suggests that gut bacteria-derived metabolites interact with the cardiovascular system and alter blood pressure (BP) in mammals. Here, we evaluated the effect of indole-3-propionic acid (IPA), a gut bacteria-derived metabolite of tryptophan, on the circulatory system. Methods. Arterial BP, electrocardiographic and echocardiographic (ECHO) parameters were recorded in male, anesthetized, 12-week-old Wistar-Kyoto rats at baseline and after intravenous administration of either IPA or vehicle. In additional experiments, rats were pretreated with prazosin or pentolinium to evaluate the involvement of the autonomic nervous system in cardiovascular responses to IPA. IPA's concentrations were measured using UHPLC-MS. The reactivity of endothelium-intact and -denuded mesenteric resistance arteries was tested. Cells' viability and LDH cytotoxicity assays were performed on cultured cardiomyocytes. Results. IPA increased BP with a concomitant bradycardic response but no significant change in QTc interval. The pretreatment with prazosin and pentolinium reduced the hypertensive response. ECHO showed increased contractility of the heart after the administration of IPA. Ex vivo, IPA constricted pre-dilated and endothelium-denuded mesenteric resistance arteries and increased metabolic activity of cardiomyocytes. Conclusions. IPA increases BP via cardiac and vascular mechanisms in rats. Furthermore, IPA increases cardiac contractility and metabolic activity of cardiomyocytes. Our study suggests that IPA may act as a mediator between gut microbiota and the circulatory system.

scholarly journals Non-Invasive Risk Stratification of Hypertension: A Systematic Comparison of Machine Learning Algorithms

2020 ◽  
Vol 9 (3) ◽  
pp. 34
Author(s):  
Giovanna Sannino ◽  
Ivanoe De Falco ◽  
Giuseppe De Pietro
Keyword(s):  
Machine Learning ◽  
Blood Pressure ◽  
Risk Stratification ◽  
Learning Algorithms ◽  
Circulatory System ◽  
Machine Learning Algorithms ◽  
Learning Mechanisms ◽  
Data Set ◽  
Non Invasive ◽  
Blood Pressure Estimation

One of the most important physiological parameters of the cardiovascular circulatory system is Blood Pressure. Several diseases are related to long-term abnormal blood pressure, i.e., hypertension; therefore, the early detection and assessment of this condition are crucial. The identification of hypertension, and, even more the evaluation of its risk stratification, by using wearable monitoring devices are now more realistic thanks to the advancements in Internet of Things, the improvements of digital sensors that are becoming more and more miniaturized, and the development of new signal processing and machine learning algorithms. In this scenario, a suitable biomedical signal is represented by the PhotoPlethysmoGraphy (PPG) signal. It can be acquired by using a simple, cheap, and wearable device, and can be used to evaluate several aspects of the cardiovascular system, e.g., the detection of abnormal heart rate, respiration rate, blood pressure, oxygen saturation, and so on. In this paper, we take into account the Cuff-Less Blood Pressure Estimation Data Set that contains, among others, PPG signals coming from a set of subjects, as well as the Blood Pressure values of the latter that is the hypertension level. Our aim is to investigate whether or not machine learning methods applied to these PPG signals can provide better results for the non-invasive classification and evaluation of subjects’ hypertension levels. To this aim, we have availed ourselves of a wide set of machine learning algorithms, based on different learning mechanisms, and have compared their results in terms of the effectiveness of the classification obtained.

Respiratory and circulatory effects of parietal pleural afferent stimulation in rabbits

2006 ◽  
Vol 100 (5) ◽  
pp. 1539-1546 ◽  
Author(s):  
Yves Jammes ◽  
Stéphane Delpierre
Keyword(s):  
Blood Pressure ◽  
Lactic Acid ◽  
Mechanical Stimulation ◽  
Circulatory System ◽  
Transpulmonary Pressure ◽  
Systemic Arterial Pressure ◽  
Parietal Pleura ◽  
Pleural Diseases ◽  
Circulatory Effects ◽  
Arterial Blood

Respiratory symptoms accompanying pleural diseases combine dyspnea, tachypnea, rapid shallow breathing, and sometimes hypotension. There are no experimental data on the changes in respiratory and circulatory functions elicited by the activation of pleural afferents. After removal of all muscles covering the 5th to 10th intercostal spaces, we investigated in paralyzed, vagotomized rabbits the changes in phrenic discharge, transpulmonary pressure, and systemic arterial pressure in response to an outwardly directed force exerted on the parietal pleura or the local application of solutions containing lactic acid or inflammatory mediators. Mechanical stimulation of the pleura induced an immediate decrease in both integrated phrenic discharge and arterial blood pressure, the responses being positively correlated with the magnitude of force applied on the pleura. No accompanying changes in ventilatory timing, transpulmonary pressure, or heart rate were measured. Lactic acid solution also elicited an inhibition of phrenic activity and a fall in blood pressure. Section of the internal intercostal nerves supplying the stimulated intercostal spaces totally abolished the responses to mechanical stimulation or lactic acid. An inflammatory mixture elicited only modest respiratory and circulatory effects. We concluded that an acute mechanical distension of the parietal pleura as well as its chemical stimulation by lactic acid elicit a marked inhibition of phrenic motoneurons combined to a reduction of the sympathetic outflow to the circulatory system.

Osteogenesis bioassay and immunohistochemical and radioisotopic studies of parotin, parotid gland extract, and subunit

1984 ◽  
Vol 40 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Isao Iwasaki ◽  
Hiroshi Horie ◽  
Junichi Tamaru ◽  
Genshiro Ide ◽  
Shigeru Aonuma
Keyword(s):  
Parotid Gland ◽  
Gland Extract
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