scholarly journals Development of Rapid Genotyping Methods for Single Nucleotide Polymorphisms of Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19) and Their Clinical Application in Pediatric Patients with Epilepsy

2011 ◽  
Vol 131 (5) ◽  
pp. 809-815 ◽  
Author(s):  
Yoshiaki YAMAMOTO ◽  
Yukitoshi TAKAHASHI ◽  
Shigeko NISHIMURA ◽  
Yasuhiro IKUMI ◽  
Nobuyuki MISHIMA ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Single Nucleotide Polymorphisms ◽  
Clinical Application ◽  
Pediatric Patients ◽  
Nucleotide Polymorphisms ◽  
Cytochrome P450 2C9 ◽  
Single Nucleotide ◽  
Cytochrome P450 2C19 ◽  
Patients With Epilepsy

scholarly journals Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9

Biochemistry ◽  
2017 ◽  
Vol 56 (41) ◽  
pp. 5476-5480 ◽  
Author(s):  
Keiko Maekawa ◽  
Motoyasu Adachi ◽  
Yumiko Matsuzawa ◽  
Qinghai Zhang ◽  
Ryota Kuroki ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Single Nucleotide Polymorphisms ◽  
Structural Basis ◽  
Nucleotide Polymorphisms ◽  
Cytochrome P450 2C9 ◽  
Single Nucleotide

scholarly journals Association of gastric cancer with cytochrome P450 2C19 single-nucleotide polymorphisms in Koreans

2007 ◽  
Vol 7 (4) ◽  
pp. 357-362
Author(s):  
Hyun-Ju Kim ◽  
Hye-Jung Park ◽  
Sang-Gyu Lee ◽  
Hye-Suk Lee ◽  
Won-Cheol Park ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cytochrome P450 ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Cytochrome P450 2C19

scholarly journals Polymorphisms in the cytochrome P450 CYP1A1, CYP1A2, CYP1B1 genes and risk of colorectal cancer in a population from Central Russia

2020 ◽  
pp. 60-61
Author(s):  
А.С. Москалев ◽  
Ф.В. Подольский ◽  
С.М. Зайцев ◽  
Е.А. Новикова ◽  
А.В. Полоников ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cytochrome P450 ◽  
Single Nucleotide Polymorphisms ◽  
Healthy Controls ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Central Russia ◽  
Increased Risk ◽  
Age And Sex

В исследование были включены 256 пациентов с колоректальным раком (134 мужчины, 122 женщины) и 608 практически здоровых добровольцев (279 мужчин, 329 женщин). Генотипирование однонуклеотидных полиморфизмов I462V (rs1048943) CYP1A1, -154A>C (rs762551) CYP1A2 и L432V (rs1056836) CYP1B1 было проведено методом ПЦР в режиме реального времени. Полиморфизм rs1056836 CYP1B1 (замена L432V) ассоциировался с повышенным риском колоректального рака в популяции Центральной России: OR=1,48, 95%CI=1,07-2,04; р=0,02. A total of 256 patients with colorectal cancer (134 males, 122 females) and 608 age- and sex-matched healthy controls (279 males, 329 females) were recruited for the study. Genotyping of single nucleotide polymorphisms (SNPs) I462V (rs1048943) CYP1A1, -154A>C (rs762551) CYP1A2 and L432V (rs1056836) CYP1B1 were done using Taq-Man-based assays. Polymorphism rs1056836 (substitution L432V) CYP1B1 was associated with increased risk of colorectal cancer in the population from Central Russia: OR=1,48, 95%CI=1,07-2,04; p=0,02.

scholarly journals The Impact of Genetic Variability of CYP1A2, ADORA2A, and AHR on Caffeine Consumption and Response among Adult New Zealanders

Proceedings ◽  
2019 ◽  
Vol 37 (1) ◽  
pp. 30
Author(s):  
Tennent ◽  
Rutherfurd-Markwick ◽  
Ali ◽  
Wham
Keyword(s):  
Cytochrome P450 ◽  
Genetic Variability ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Caffeine Consumption ◽  
Cytochrome P450 1A2 ◽  
Single Nucleotide ◽  
The Impact ◽  
New Zealanders

Three single nucleotide polymorphisms (SNPs) have known links to caffeine consumption,metabolism, and post-consumption effects and responses: cytochrome P450 1A2 (CYP1A2; rs762551) [...]

Sign in / Sign up

Export Citation Format

Share Document