scholarly journals Beneficial Effects of Donepezil on Vascular Endothelial Dysfunction-Associated Dementia Induced by L-Methionine in Rats

2009 ◽  
Vol 55 (2) ◽  
pp. 215-225 ◽  
Author(s):  
Rajeshkumar Ukabhi Koladiya ◽  
Amteshwar Singh Jaggi ◽  
Nirmal Singh ◽  
Bhupesh Kumar Sharma
Keyword(s):  
Endothelial Dysfunction ◽  
Vascular Endothelial ◽  
Vascular Endothelial Dysfunction ◽  
Beneficial Effects

Beneficial effects of apple peel polyphenols on vascular endothelial dysfunction and liver injury in high choline-fed mice

2017 ◽  
Vol 8 (3) ◽  
pp. 1282-1292 ◽  
Author(s):  
Mengfan Jia ◽  
Daoyuan Ren ◽  
Yan Nie ◽  
Xingbin Yang
Keyword(s):  
Endothelial Dysfunction ◽  
Liver Injury ◽  
Hepatic Injury ◽  
Vascular Dysfunction ◽  
Vascular Endothelial ◽  
Vascular Endothelial Dysfunction ◽  
Beneficial Effects ◽  
Apple Peel

APP could ameliorate HC diet-induced vascular dysfunction and hepatic injury.

Vascular endothelial dysfunction: does tetrahydrobiopterin play a role?

2001 ◽  
Vol 281 (3) ◽  
pp. H981-H986 ◽  
Author(s):  
Zvonimir S. Katusic
Keyword(s):  
Nitric Oxide ◽  
Endothelial Dysfunction ◽  
Vascular Function ◽  
Ischemia Reperfusion ◽  
Vascular Endothelial ◽  
Vascular Endothelial Dysfunction ◽  
Vascular Effects ◽  
Beneficial Effects ◽  
Oxide Synthase

Tetrahydrobiopterin is one of the most potent naturally occurring reducing agents and an essential cofactor required for enzymatic activity of nitric oxide synthase (NOS). The exact role of tetrahydrobiopterin in the control of NOS catalytic activity is not completely understood. Existing evidence suggests that it can act as alosteric and redox cofactors. Suboptimal concentration of tetrahydrobiopterin reduces formation of nitric oxide and favors “uncoupling” of NOS leading to NOS-mediated reduction of oxygen and formation of superoxide anions and hydrogen peroxide. Recent findings suggest that accelerated catabolism of tetrahydrobiopterin in arteries exposed to oxidative stress may contribute to pathogenesis of endothelial dysfunction present in arteries exposed to hypertension, hypercholesterolemia, diabetes, smoking, and ischemia-reperfusion. Beneficial effects of acute and chronic tetrahydrobiopterin supplementation on endothelial function have been reported in experimental animals and humans. Furthermore, it appears that beneficial effects of some antioxidants (e.g., vitamin C) on vascular function could be mediated via increased intracellular concentration of tetrahydrobiopterin. In this review, the potential role of tetrahydrobiopterin in the pathogenesis of vascular endothelial dysfunction and mechanisms underlying beneficial vascular effects of tetrahydrobiopterin will be discussed.

Hsa_circ_0008360 sponges miR-186-5p to target CCND2 to modulate high glucose-induced vascular endothelial dysfunction

Cell Cycle ◽  
2021 ◽  
pp. 1-13
Author(s):  
Qian-Qian Zhu ◽  
Xi-Bin Pu ◽  
Tian-Chi Chen ◽  
Chen-Yang Qiu ◽  
Zi-Heng Wu ◽  
...  
Keyword(s):  
Endothelial Dysfunction ◽  
High Glucose ◽  
Vascular Endothelial ◽  
Vascular Endothelial Dysfunction

scholarly journals Ebselen reduces cigarette smoke‐induced vascular endothelial dysfunction in mice

2021 ◽  
Author(s):  
Kurt Brassington ◽  
Stanley M.H. Chan ◽  
Huei Jiunn Seow ◽  
Aleksandar Dobric ◽  
Steven Bozinovski ◽  
...  
Keyword(s):  
Endothelial Dysfunction ◽  
Cigarette Smoke ◽  
Vascular Endothelial ◽  
Vascular Endothelial Dysfunction

Peroxynitrite and Vascular Endothelial Dysfunction in Diabetes Mellitus

Endothelium ◽  
2004 ◽  
Vol 11 (2) ◽  
pp. 89-97 ◽  
Author(s):  
Ming-Hui Zou ◽  
Richard A. Cohen ◽  
Volker Ullrich
Keyword(s):  
Diabetes Mellitus ◽  
Endothelial Dysfunction ◽  
Vascular Endothelial ◽  
Vascular Endothelial Dysfunction

scholarly journals Vascular endothelial dysfunction in Duchenne muscular dystrophy is restored by bradykinin through upregulation of eNOS and nNOS

2011 ◽  
Vol 107 (1) ◽  
Author(s):  
Hubert Dabiré ◽  
Inès Barthélémy ◽  
Nicolas Blanchard-Gutton ◽  
Lucien Sambin ◽  
Carolina Carlos Sampedrano ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Endothelial Dysfunction ◽  
Muscular Dystrophy ◽  
Vascular Endothelial ◽  
Vascular Endothelial Dysfunction
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