scholarly journals Evaluation of Serum Protein Binding by Using in Vitro Pharmacological Activity for the Effective Pharmacokinetics Profiling in Drug Discovery

2010 ◽  
Vol 58 (8) ◽  
pp. 1051-1056
Author(s):  
Yukinori Kawai ◽  
Yoshimine Fujii ◽  
Katsuya Akimoto ◽  
Masayuki Takahashi
Keyword(s):  
Drug Discovery ◽  
Protein Binding ◽  
Serum Protein ◽  
Pharmacological Activity ◽  
Serum Protein Binding

Influence of Age and Gender on the In Vitro Serum Protein Binding of Flecainide

1993 ◽  
Vol 28 (3) ◽  
pp. 259-264 ◽  
Author(s):  
R. Zordan ◽  
R. Padrini ◽  
V. Bernini ◽  
D. Piovan ◽  
M. Ferrari
Keyword(s):  
Protein Binding ◽  
Serum Protein ◽  
Serum Protein Binding ◽  
Age And Gender ◽  
And Gender

scholarly journals In Vivo and in Vitro Serum Protein Binding of Sulfonamides in Rabbits

1985 ◽  
Vol 105 (12) ◽  
pp. 1188-1191
Author(s):  
YORISHIGE IMAMURA ◽  
RAMONLOO ELIO ◽  
HIROYUKI MORI ◽  
MASAKI OTAGIRI
Keyword(s):  
Protein Binding ◽  
Serum Protein ◽  
Serum Protein Binding

A simple method for predicting serum protein binding of compounds from IC 50 shift analysis for in vitro assays

2004 ◽  
Vol 14 (9) ◽  
pp. 2309-2312 ◽  
Author(s):  
David W. Rusnak ◽  
Zhihong Lai ◽  
Timothy J. Lansing ◽  
Nelson Rhodes ◽  
Tona M. Gilmer ◽  
...  
Keyword(s):  
Protein Binding ◽  
Serum Protein ◽  
In Vitro Assays ◽  
Serum Protein Binding ◽  
Simple Method ◽  
Shift Analysis
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