scholarly journals Antimalarial Activity of Sesquiterpene Lactones from Vernonia cinerea

2006 ◽  
Vol 54 (10) ◽  
pp. 1437-1439 ◽  
Author(s):  
Aun Chea ◽  
Sotheara Hout ◽  
Christophe Long ◽  
Laurence Marcourt ◽  
Robert Faure ◽  
...  
ChemInform ◽  
2007 ◽  
Vol 38 (14) ◽  
Author(s):  
Aun Chea ◽  
Sotheara Hout ◽  
Christophe Long ◽  
Laurence Marcourt ◽  
Robert Faure ◽  
...  

Fitoterapia ◽  
2014 ◽  
Vol 93 ◽  
pp. 194-200 ◽  
Author(s):  
Ui Joung Youn ◽  
Gabriella Miklossy ◽  
Xingyun Chai ◽  
Supakit Wongwiwatthananukit ◽  
Onoomar Toyama ◽  
...  

2017 ◽  
Vol 32 (1) ◽  
pp. 1136-1142 ◽  
Author(s):  
Supattra Boonruang ◽  
Khanistha Prakobsri ◽  
Phisit Pouyfung ◽  
Ekaruth Srisook ◽  
Aruna Prasopthum ◽  
...  

2018 ◽  
Vol 54 (2) ◽  
pp. 235-237
Author(s):  
Ui Joung Youn ◽  
Supakit Wongwiwatthananukit ◽  
Thanapat Songsak ◽  
Leng Chee Chang

ChemInform ◽  
2003 ◽  
Vol 34 (37) ◽  
Author(s):  
Yao-Haur Kuo ◽  
Yu-Jen Kuo ◽  
Ang-Su Yu ◽  
Ming-Der Wu ◽  
Chi-Wi Ong ◽  
...  

2004 ◽  
Vol 95 (2-3) ◽  
pp. 455-457 ◽  
Author(s):  
Theodore A. Bischoff ◽  
Charles J. Kelley ◽  
Yvette Karchesy ◽  
Maria Laurantos ◽  
Phuc Nguyen-Dinh ◽  
...  

2019 ◽  
Vol 82 (8) ◽  
pp. 2124-2131 ◽  
Author(s):  
Mengke Zhang ◽  
Xi Yang ◽  
Yanzhang Wei ◽  
Marisa Wall ◽  
Thanapat Songsak ◽  
...  

2014 ◽  
Vol 9 (10) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Yixi Liu ◽  
L. Harinantenaina Rakotondraibe ◽  
Peggy J. Brodie ◽  
Jessica D. Wiley ◽  
Maria B. Cassera ◽  
...  

Bioassay-directed fractionation of an antiproliferative ethanol extract of the leaves and twigs of Piptocoma antillana (Asteraceae) afforded two new goyazensolide-type sesquiterpene lactones named 5- O-methyl-5-epiisogoyazensolide (1) and 15- O-methylgoyazensolide (2), together with the known compounds 1-oxo-3,10-epoxy-8-(2-methylacryloxy)-15-acetoxygermacra-2,4,11(13)-trien-6(12)-olide (3) and 5-epiisogoyazensolide (4). The structure elucidation of all compounds was carried out based on NMR and mass spectroscopic data analyses. The relative and absolute configurations of all the isolated compounds were determined from their CD and NOESY NMR spectra. Compounds 1–4 showed moderately potent antiproliferative activities against A2780 ovarian cancer cells, with IC50 values of 1.5 ±0.5, 0.6 ± 0.3, 1.62 ± 0.05, and 1.56 ± 0.04 μM, respectively. They also displayed antimalarial activity against Plasmodium falciparum, with IC50 values of 6.2 ± 0.5, 2.2 ± 0.5, 8.0 ± 0.4, and 9.0 ± 0.6 μM, respectively.


2003 ◽  
Vol 51 (4) ◽  
pp. 425-426 ◽  
Author(s):  
Yao-Haur Kuo ◽  
Yu-Jen Kuo ◽  
Ang-Su Yu ◽  
Ming-Der Wu ◽  
Chi-Wi Ong ◽  
...  

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