scholarly journals Hydrophobicity Parameters Determined by Reversed-Phase Liquid Chromatography. XII. Comparison of Capacity Factors and Octane/Methanol-Water Partition Coefficients for Monosubstituted Pyrazines, and Effect of Octanol Added to both Partitioning Systems.

1997 ◽  
Vol 45 (10) ◽  
pp. 1653-1658 ◽  
Author(s):  
Chisako YAMAGAMI ◽  
Kaname IWASAKI ◽  
Ayako ISHIKAWA
2004 ◽  
pp. 165-177 ◽  
Author(s):  
Marijana Acanski ◽  
Tatjana Djakovic-Sekulic

Several calculation procedures for log P values based on the fragmental and atomic contributions are compared with experimental reversed-phase liquid chromatography (RPLC) retention constants of benzimidazole derivatives. The RPLC experiments were performed on HPLC comerrcially available LiChrosorb RP(-18 column with binary solvent mixtures of methanol-phosphate buffer (pH 7) as mobile phase. Retention constant log k0 was determined by the extrapolation method. Good correlaton was found between the retention constants log k0 and log P, as well as m and log P of the compounds investigated.


Author(s):  
Ling DING ◽  
Jun DONG ◽  
Yuan-Sheng XIAO ◽  
Xiu-Li ZHANG ◽  
Xing-Ya XUE ◽  
...  

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