scholarly journals Effect of Granule Strength on Compressed Tablet Strength.

1995 ◽  
Vol 43 (12) ◽  
pp. 2261-2263 ◽  
Author(s):  
Eijiro HORISAWA ◽  
Akio KOMURA ◽  
Kazumi DANJO ◽  
Akinobu OTSUKA
2002 ◽  
Vol 1 (1) ◽  
pp. 86-101 ◽  
Author(s):  
Jason Ditton

Extensive forensic examination of the hair of 209 'Ecstasy' (MDMA) users demonstrated virtually no correlation between self-reported tablet use, and traces of MDMA in the hair of users. Why should this be so? Three answers are possible, and all true. First, self-report is fallible; second, tablet strength varies enormously; and third, forensic analysis is of unknown accuracy. The first two are well known. Forensic analysis, however, typically presents itself as impeccably precise. The article demonstrates that not only is this claim spectacularly untrue, but also that validation of forensic analysis (and, thus, indirectly, self-report) lies in the very blind intra- and inter- laboratory comparisons that are never undertaken.


2018 ◽  
Vol 5 (1) ◽  
pp. 1-6
Author(s):  
Forder S ◽  
Voelker M

Migraine is a global disorder and considerably affecting people`s quality of life. Treatments include nonsteroidal anti-inflammatory drugs-containing medicinal products among whom acetylsalicylic acid-containing Aspirin® has been proven effectively to relief migraine headache. Early treatment is recommended for patients with migraine attacks. A requirement for early onset of action includes tablet disintegration and consequent active ingredient dissolution and absorption. The bioavailability of a new quickly disintegrating 1,000 mg aspirin formulation has been investigated in a bioequivalence study versus a marketed Aspirin® formulation with clinically demonstrated early onset of action. The new formulation has a tablet strength (1,000 mg) and time to maximum plasma concentration (mean 21.6 minutes) providing upside for people requiring treatment of migraine headache


2020 ◽  
Vol 147 ◽  
pp. 105292 ◽  
Author(s):  
Nizar Al-Zoubi ◽  
Adel Ardakani ◽  
Faten Odeh ◽  
Nina Sakhnini ◽  
Ioannis Partheniadis ◽  
...  

1974 ◽  
Vol 63 (4) ◽  
pp. IV
Author(s):  
J.W. Newton

2010 ◽  
Vol 62 ◽  
pp. 157-162
Author(s):  
Susanna Eckhard ◽  
Manfred Fries

Three different batches of ceramic alumina granules were produced using a spray dryer in laboratory scale. The suspensions containing identical solid contents and amounts of binders were modified by adding nitric acid to get different stabilized conditions. The granules were analyzed concerning micro and macro structural properties by image analysis on specially prepared granule cross-sections. The investigated structure parameters were correlated with the studied mechanical properties using a commercially granule strength tester. Different measured fracture forces were explained by varied macro structures (parameter H, amount of hollow and homogeneous granules and average shell thickness) as a result of modified suspension properties.


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