scholarly journals Renin Inhibitors. I. Synthesis and Structure-Activity Relationships of Transition-State Inhibitors Containing Homostatine Analogues at the Scissile Bond.

1992 ◽  
Vol 40 (2) ◽  
pp. 364-370 ◽  
Author(s):  
Shugo ATSUUMI ◽  
Masato NAKANO ◽  
Yutaka KOIKE ◽  
Seiichi TANAKA ◽  
Kenji MATSUYAMA ◽  
...  
Keyword(s):  
Transition State ◽  
Renin Inhibitors ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Scissile Bond

scholarly journals Synthesis and structure-activity relationships of human renin inhibitors designed from angiotensinogen transition state.

1990 ◽  
Vol 38 (9) ◽  
pp. 2487-2493 ◽  
Author(s):  
Kinji IIZUKA ◽  
Tetsuhide KAMIJO ◽  
Hiromu HARADA ◽  
Kenji AKAHANE ◽  
Tetsuhiro KUBOTA ◽  
...  
Keyword(s):  
Transition State ◽  
Renin Inhibitors ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Human Renin

Renin inhibitors. Synthesis of transition-state analog inhibitors containing phosphorus acid derivatives at the scissile bond

1989 ◽  
Vol 32 (7) ◽  
pp. 1652-1661 ◽  
Author(s):  
Mark C. Allen ◽  
Walter Fuhrer ◽  
Brian Tuck ◽  
Roy Wade ◽  
Jeanette M. Wood
Keyword(s):  
Transition State ◽  
Phosphorus Acid ◽  
Transition State Analog ◽  
Renin Inhibitors ◽  
Scissile Bond

Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

1992 ◽  
Vol 35 (14) ◽  
pp. 2562-2572 ◽  
Author(s):  
William C. Patt ◽  
Harriet W. Hamilton ◽  
Michael D. Taylor ◽  
Michael J. Ryan ◽  
David G. Taylor ◽  
...  
Keyword(s):  
Renin Inhibitors ◽  
Structure Activity Relationships ◽  
Structure Activity

Renin inhibitors. Dipeptide analogs of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency

1988 ◽  
Vol 31 (12) ◽  
pp. 2264-2276 ◽  
Author(s):  
Jay R. Luly ◽  
Nwe BaMaung ◽  
Jeff Soderquist ◽  
Anthony K. L. Fung ◽  
Herman Stein ◽  
...  
Keyword(s):  
Transition State ◽  
Inhibitory Potency ◽  
Renin Inhibitors ◽  
Scissile Bond

Renin inhibitors. Dipeptide analogs of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond

1987 ◽  
Vol 30 (10) ◽  
pp. 1729-1737 ◽  
Author(s):  
Giorgio Bolis ◽  
Anthony K. L. Fung ◽  
Jonathan Greer ◽  
Hollis D. Kleinert ◽  
Patrick A. Marcotte ◽  
...  
Keyword(s):  
Transition State ◽  
Renin Inhibitors ◽  
Scissile Bond

Benzyl ether structure–activity relationships in a series of ketopiperazine-based renin inhibitors

2005 ◽  
Vol 15 (21) ◽  
pp. 4713-4716 ◽  
Author(s):  
Noel A. Powell ◽  
Emma H. Clay ◽  
Daniel D. Holsworth ◽  
John W. Bryant ◽  
Michael J. Ryan ◽  
...  
Keyword(s):  
Benzyl Ether ◽  
Renin Inhibitors ◽  
Structure Activity Relationships ◽  
Structure Activity
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