Inhibition of Urease Activity by Dipeptidyl Hydroxamic Acids.

1992 ◽  
Vol 40 (10) ◽  
pp. 2764-2768 ◽  
Author(s):  
Shinjiro ODAKE ◽  
Kazuaki NAKAHASHI ◽  
Tadanori MORIKAWA ◽  
Sachiko TAKEBE ◽  
Kyoichi KOBASHI
Keyword(s):  
Urease Activity ◽  
Hydroxamic Acids

Effect of hydroxamic acids on growth and urease activity in Corynebacterium renale

1976 ◽  
Vol 22 (4) ◽  
pp. 544-551 ◽  
Author(s):  
Robert M. Nervig ◽  
Solomon Kadis
Keyword(s):  
Urease Activity ◽  
Hydroxamic Acids ◽  
Terminal Group ◽  
Side Chain ◽  
Acetohydroxamic Acid ◽  
Maximal Growth ◽  
Maximal Inhibition ◽  
Intact Cells ◽  
Lag Period ◽  
The Common

Studies were conducted on the effect of four different hydroxamic acids (HA), hydroxyurea, acetohydroxamic acid, p-fluorobenzoylhydroxamic acid and sorbylhydroxamic acid, on the growth and urease activity of Corynebacterium renale. The addition of each of these HA, at concentrations ranging from 10−3 to 10−5 M, to medium containing urea as the sole nitrogen source resulted in a lengthened lag period of growth the extent of which depended upon the concentration of each HA tested as well as the structure of the compound; that is, the size and (or) complexity of the side chain attached to the common terminal group of the molecule. However, the maximal growth levels achieved following conclusion of the exponential phase were not affected by the HA. Investigations on the effect of these HA on the urease activity of intact cells as well as cell-free extracts revealed that in each case the enzymatic activity was inhibited by each of the HA tested. The extent of inhibition with the intact cells was about one-half of that observed with cell-free extracts. Direct incubation of cell-free extracts as well as intact cells with each of the HA tested was required for maximal inhibition.

N-acetyl-cysteine and H. pylori urease activity

2001 ◽  
Vol 120 (5) ◽  
pp. A589-A589
Author(s):  
H HUYNH ◽  
R COUPER ◽  
C TRAN ◽  
A MUHAMED ◽  
R BUTLER
Keyword(s):  
Urease Activity ◽  
Acetyl Cysteine ◽  
H Pylori

Diagnosis of helicobacter pylori infection: problems and prospects

2020 ◽  
pp. 54-59
Author(s):  
A. S. Molostova ◽  
N. S. Gladyshev ◽  
A. V. Svarval ◽  
R. S. Ferman ◽  
A. B. Karasyova ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Urease Activity ◽  
Diagnostic Methods ◽  
Study Group ◽  
Biochemical Method ◽  
Antimicrobial Drugs ◽  
Non Invasive ◽  
Number Of Patients ◽  
Pcr Method ◽  
Positive Results

(HP) infection was performed using invasive and non-invasive methods. The study group consisted of 95 patients with dyspepsia. HP infection was detected in 47 patients (49.4 %). The expediency of using a set of diagnostic methods for detecting HP (PCR, immunochromatographic, bacteriological and method for determining urease activity) is proved. Most often (100 %) in patients HP infection was detected in biopsies using the PCR method. Somewhat less frequently it was detected when examining biopsies with an invasive biochemical method (AMA RUT Reader) (82 %) and fecal immunochromatographic method (83 %). Despite the fact that helicobacteriosis was detected bacteriologically in a small number of patients (24 %), this method is of particular value, since it allows you to assess the sensitivity to antimicrobial drugs and probiotics, and does not give false positive results.

Determination of the prevalence of helicobacter pylori oral infection in smoking patients with chronic generalized periodontitis on the background of chronic hyperacidal gastritis during treatment

2020 ◽  
Vol 40 (4) ◽  
pp. 50-54
Author(s):  
O. L. Zolotukhina ◽  
◽  
Ju. G. Romanova ◽  
O. V. Maslov ◽  
◽  
...  
Keyword(s):  
Risk Factors ◽  
Helicobacter Pylori ◽  
Oral Cavity ◽  
Urease Activity ◽  
Rapid Test ◽  
Oral Infection ◽  
Helicobacter Pylori Infection ◽  
Natural Origin ◽  
Periodontal Tissues

Diseases of periodontal tissues occupy one of the leading positions among modern dental problems, namely the multifactorial nature of these diseases. In modern dental science, the issue of the development of periodontal pathology against the background of somatic pathology and risk factors remains relevant. Pathology of periodontal tissues in 68–90 % of cases is accompanied by chronic diseases of the gastrointestinal tract. Today, there is no doubt that Helicobacter pylori infection can be present in the biotopes of the oral cavity and can affect the course of periodontal pathology. As you know, smoking is one of the important risk factors for the development of inflammatory-dystrophic diseases of periodontal tissues, which can aggravate the course of the latter. The purpose of the work is to determine the prevalence of oral Helicobacter pylori infection in tobacco-dependent patients with chronic generalized periodontitis on the background of chronic hyperacid gastritis during treatment. Patients who received the proposed therapeutic and prophylactic complex (ultraphonophoresis procedures with the created gel «Apisan», and probiotic drug BioGaia ProDentis and angioprotective drug of natural origin — Detralex) showed a gradual decrease in the level of total urease activity and, as a consequence, a decrease the prevalence of Helicobacter pylori infection in the oral cavity according to the results of a urease rapid test with material from the oral cavity, both in the presence of a risk factor — smoking, and in its absence. The use of the proposed therapeutic and prophylactic complex proved to be effective in reducing the prevalence of oral Helicobacter pylori infection in smoking patients and patients who do not smoke, with chronic generalized periodontitis against the background of chronic hyperacidal gastritis associated with Helicobacter pylori.

Urease activity in soils

1976 ◽  
Author(s):  
Manuel Ibarbia Zantua
Keyword(s):  
Urease Activity

BIOMODIFICATION OF BUILDING MATERIALS BY BACTERIA WITH UREASE ACTIVITY

2020 ◽  
Vol 88 (2) ◽  
pp. 5-15
Author(s):  
M.G. BRUYAKO ◽  
◽  
A.I. GRIGOREVA ◽  
D.S. GOLOTENKO ◽  
A.А. PODSEVALOVA ◽  
...  
Keyword(s):  
Building Materials ◽  
Urease Activity

Urease as a Possible Tracer for Sewage Effluent Plumes

1989 ◽  
Vol 21 (2) ◽  
pp. 93-97 ◽  
Author(s):  
R. Sadler
Keyword(s):  
Urease Activity ◽  
Simple Procedure ◽  
Sewage Treatment ◽  
Sewage Treatment Plant ◽  
Treatment Plant ◽  
Particulate Phase ◽  
Untreated Sewage ◽  
Potential Alternative ◽  
Two Parameters ◽  
Point Source Discharges

The suitability of sedimentary urease activity as a potential tracer for sewage outfall plumes has been examined. Enzyme activity is readily measured in the sediments by a relatively simple procedure and results may be obtained within a few hours of sampling. The results of urease measurements in areas around point source discharges were compared with bacteriological data for the same areas. Three areas were selected for study: a discharge of untreated sewage into a harbour, a discharge from a sewage treatment plant to a river and a discharge from a contaminated drain to a small beach. In all cases, positive correlation between the distribution of the two parameters was observed. Urease activity probably reflects the movement of soluble products from the outfall whereas E.coli represents the particulate phase of the discharge. Although further work will be required, urease activity does offer a potential alternative to E.coli for tracing plumes of faecal pollution.

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