Studies on Antiulcer Drugs. VI. 4-Furyl-2-guanidinothiazoles and Related Compounds as Potent Histamine H2-Receptor Antagonists.

Yousuke KATSURA; Yoshikazu INOUE; Tetsuo TOMISI; Harunobu ITOH; Hirohumi ISHIKAWA; Hisashi TAKASUGI

doi:10.1248/cpb.40.2432

Studies on Antiulcer Drugs. VI. 4-Furyl-2-guanidinothiazoles and Related Compounds as Potent Histamine H2-Receptor Antagonists.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.40.2432 ◽

1992 ◽

Vol 40 (9) ◽

pp. 2432-2441 ◽

Cited By ~ 13

Author(s):

Yousuke KATSURA ◽

Yoshikazu INOUE ◽

Tetsuo TOMISI ◽

Harunobu ITOH ◽

Hirohumi ISHIKAWA ◽

...

Keyword(s):

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Antiulcer Drugs ◽

Related Compounds

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Studies on Antiulcer Drugs. III. Synthesis and Antiulcer Activities of Imidazo(1,2-a)pyridinylethylbenzoxazoles and Related Compounds. A Novel Class of Histamine H2-Receptor Antagonists.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.40.1424 ◽

1992 ◽

Vol 40 (6) ◽

pp. 1424-1438 ◽

Cited By ~ 25

Author(s):

Yousuke KATSURA ◽

Yoshikazu INOUE ◽

Sigetaka NISHINO ◽

Masaaki TOMOI ◽

Harunobu ITOH ◽

...

Keyword(s):

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Antiulcer Drugs ◽

Related Compounds

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ChemInform Abstract: Studies on Antiulcer Drugs. Part 3. Synthesis and Antiulcer Activities of Imidazo(1,2-a)pyridinylethylbenzoxazoles and Related Compounds. A Novel Class of Histamine H2-Receptor Antagonists.

ChemInform ◽

10.1002/chin.199310220 ◽

2010 ◽

Vol 24 (10) ◽

pp. no-no

Author(s):

Y. KATSURA ◽

Y. INOUE ◽

S. NISHINO ◽

M. TOMOI ◽

H. ITOH ◽

...

Keyword(s):

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Antiulcer Drugs ◽

Related Compounds

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An infrared study of intramolecular hydrogen-bonding in the histamine H2-receptor antagonists, burimamide, metiamide, cimetidine, and related compounds

Journal of the Chemical Society Perkin Transactions 2 ◽

10.1039/p29800000915 ◽

1980 ◽

pp. 915 ◽

Cited By ~ 15

Author(s):

Robert C. Mitchell

Keyword(s):

Hydrogen Bonding ◽

Intramolecular Hydrogen Bonding ◽

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Infrared Study ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Intramolecular Hydrogen ◽

Related Compounds

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Studies on antiulcer drugs. 7. 2-Guanidino-4-pyridylthiazoles as histamine H2-receptor antagonists with potent gastroprotective effects against nonsteroidal antiinflammatory drug-induced injury

Journal of Medicinal Chemistry ◽

10.1021/jm00027a007 ◽

1994 ◽

Vol 37 (1) ◽

pp. 57-66 ◽

Cited By ~ 6

Author(s):

Yousuke Katsura ◽

Yoshikazu Inoue ◽

Tetsuo Tomishi ◽

Hirohumi Ishikawa ◽

Hisashi Takasugi

Keyword(s):

Antiinflammatory Drug ◽

Nonsteroidal Antiinflammatory Drug ◽

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Drug Induced ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Antiulcer Drugs

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ChemInform Abstract: Studies on Antiulcer Drugs. Part 7. 2-Guanidino-4-pyridylthiazoles as Histamine H2-Receptor Antagonists with Potent Gastroprotective Effects Against Nonsteroidal Antiinflammatory Drug-Induced Injury.

ChemInform ◽

10.1002/chin.199417167 ◽

2010 ◽

Vol 25 (17) ◽

pp. no-no

Author(s):

Y. KATSURA ◽

Y. INOUE ◽

T. TOMISHI ◽

H. ISHIKAWA ◽

H. TAKASUGI

Keyword(s):

Antiinflammatory Drug ◽

Nonsteroidal Antiinflammatory Drug ◽

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Drug Induced ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Antiulcer Drugs

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Drugs from emasculated hormones: The principle of syntopic antagonism

Bioscience Reports ◽

10.1007/bf01114681 ◽

1989 ◽

Vol 9 (3) ◽

pp. 253-272 ◽

Cited By ~ 6

Author(s):

James Black

Keyword(s):

Future Research ◽

Receptor Antagonists ◽

Personal View ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Early Stages ◽

Β Receptor

This lecture outlines the early stages in the discovery of adrenaline β-receptor antagonists and of the histamine H2-receptor antagonists. It ends with a brief personal view about future research.

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ChemInform Abstract: CRYSTAL AND MOLECULAR STRUCTURE OF HISTAMINE H2-RECEPTOR ANTAGONISTS OF THE RANITIDINE FAMILY. PART 1. 1-(5-DIMETHYLAMINOMETHYL)FURFURYLTHIOPROPAN-2-ONE THIOSEMICARBAZONE AND 1-(5-DIMETHYLAMINOMETHYL)FURFURYLTHIOPROPAN-2-ONE 1-METHYLA

Chemischer Informationsdienst ◽

10.1002/chin.198411063 ◽

1984 ◽

Vol 15 (11) ◽

Author(s):

G. CHIARI ◽

D. VITERBO

Keyword(s):

Molecular Structure ◽

Crystal And Molecular Structure ◽

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor

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Effect of some new histamine H2-receptor antagonists on the guinea pig papillary muscle *1G. Bertaccini and G. Coruzzi. Institute of Pharmacology, University of Parma, Faculty of Medicine, Parma, Italy

Journal of Molecular and Cellular Cardiology ◽

10.1016/0022-2828(81)90017-1 ◽

1981 ◽

Vol 13 ◽

pp. 8

Keyword(s):

Guinea Pig ◽

Papillary Muscle ◽

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor

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Inhibition of gastric alcohol dehydrogenase activity by histamine H2- receptor antagonists has no influence on the pharmacokinetics of ethanol after a moderate dose.

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.1994.tb04263.x ◽

1994 ◽

Vol 37 (2) ◽

pp. 208-211 ◽

Cited By ~ 10

Author(s):

A Mallat ◽

F Roudot-Thoraval ◽

JF Bergmann ◽

H Trout ◽

G Simonneau ◽

...

Keyword(s):

Alcohol Dehydrogenase ◽

Dehydrogenase Activity ◽

Moderate Dose ◽

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Alcohol Dehydrogenase Activity ◽

Gastric Alcohol Dehydrogenase

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(Imidazolylphenyl)formamidines. A structurally novel class of potent histamine H2 receptor antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm00369a025 ◽

1984 ◽

Vol 27 (3) ◽

pp. 380-386 ◽

Cited By ~ 42

Author(s):

Arturo Donetti ◽

Enzo Cereda ◽

Elio Bellora ◽

Alberto Gallazzi ◽

Cesare Bazzano ◽

...

Keyword(s):

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Histamine H2 Receptor ◽

H2 Receptor

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