Novel phenolic amide derivative from the bulbs of Lilium regale.

Yoshihiro MIMAKI; Yutaka SASHIDA

doi:10.1248/cpb.38.541

Simple synthesis of (±)-(E)-3-(4-hydroxyphenyl)-N-[4-(3-methyl-2,5-dioxo-1-pyrrolidinyl)butyl]-2-propenamide, a novel phenolic amide derivative from the bulbs of Lilium regale WILSON

Tetrahedron ◽

10.1016/s0040-4020(01)81286-2 ◽

1993 ◽

Vol 49 (21) ◽

pp. 4575-4580 ◽

Cited By ~ 8

Author(s):

Paul Kuehne ◽

Manfred Hesse

Keyword(s):

Simple Synthesis ◽

Amide Derivative ◽

Lilium Regale ◽

Lilium Regale Wilson

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ChemInform Abstract: Simple Synthesis of (.+-.)-(E)-3-(4-Hydroxyphenyl)-N-(4-(3-methyl-2,5- dioxo-1-pyrrolidinyl)butyl)-2-propenamide, a Novel Phenolic Amide Derivative from the Bulbs of Lilium regale WILSON.

ChemInform ◽

10.1002/chin.199341268 ◽

2010 ◽

Vol 24 (41) ◽

pp. no-no

Author(s):

P. KUEHNE ◽

M. HESSE

Keyword(s):

Simple Synthesis ◽

Amide Derivative ◽

Lilium Regale ◽

Lilium Regale Wilson

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4-[(2,4-Dichlorophenyl)carbamoyl]butanoic Acid

Molbank ◽

10.3390/m1227 ◽

2021 ◽

Vol 2021 (2) ◽

pp. M1227

Author(s):

Bibi Hanifa ◽

Muhammad Sirajuddin ◽

Zafran Ullah ◽

Sumera Mahboob ◽

See Mun Lee ◽

...

Keyword(s):

Torsion Angle ◽

Acid Amide ◽

Spectroscopic Characterization ◽

Amide Bond ◽

Amide Hydrogen ◽

Butanoic Acid ◽

X Ray ◽

Amide Derivative

The synthesis and spectroscopic characterization of the glutaric acid-amide derivative, 2,4-Cl2C6H3N(H)C(=O)(CH2)3C(=O)OH (1), are described. The X-ray crystal structure determination of (1) shows the backbone of the molecule to be kinked about the methylene-C–N(amide) bond as seen in the C(p)–N–C(m)–C(m) torsion angle of −157.0(2)°; m = methylene and p = phenyl. An additional twist in the molecule is noted between the amide and phenyl groups as reflected in the C(m)–N–C(p)–C(p) torsion angle of 138.2(2)°. The most prominent feature of the molecular packing is the formation of supramolecular tapes assembled through carboxylic acid-O–H…O(carbonyl) and amide-N–H…O(amide) hydrogen bonding.

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Photophysical properties of a coumarin amide derivative and its sensing for hypochlorite

Journal of Photochemistry and Photobiology A Chemistry ◽

10.1016/j.jphotochem.2021.113197 ◽

2021 ◽

Vol 411 ◽

pp. 113197

Author(s):

Panpan Li ◽

Yatong Sun ◽

Xueying Zhang ◽

Xiangwen Wu ◽

Runsen Li ◽

...

Keyword(s):

Photophysical Properties ◽

Amide Derivative

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Three previously undescribed chlorophenyl glycosides from the bulbs of Lilium regale

Chemistry & Biodiversity ◽

10.1002/cbdv.202100403 ◽

2021 ◽

Author(s):

Jie Yan ◽

Wenxiu Guo ◽

Lanyu Zhou ◽

Dale Guo ◽

Jin Pei ◽

...

Keyword(s):

Lilium Regale

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Synthesis of a novel fatty amide derivative of 7,10-dihydroxy-8(E)-octadecenoic acid by lipase-catalyzed amidation reaction

Journal of Biotechnology ◽

10.1016/j.jbiotec.2008.07.854 ◽

2008 ◽

Vol 136 ◽

pp. S371

Author(s):

Sunil K. Khare ◽

Tsung Min Kuo ◽

N.G. Ramesh

Keyword(s):

Octadecenoic Acid ◽

Fatty Amide ◽

Amide Derivative ◽

Amidation Reaction

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In vitroresponse of osteoarthritic chondrocytes and fibroblast-like synoviocytes to a 500-730 kDa hyaluronan amide derivative

Journal of Biomedical Materials Research Part B Applied Biomaterials ◽

10.1002/jbm.b.32771 ◽

2012 ◽

Vol 100B (8) ◽

pp. 2073-2081 ◽

Cited By ~ 18

Author(s):

Paola Brun ◽

Barbara Zavan ◽

Vincenzo Vindigni ◽

Antonella Schiavinato ◽

Assunta Pozzuoli ◽

...

Keyword(s):

Amide Derivative ◽

Osteoarthritic Chondrocytes ◽

Fibroblast Like Synoviocytes

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Use of New BTH Derivative as Supplement or Substitute of Standard Fungicidal Program in Strawberry Cultivation

Agronomy ◽

10.3390/agronomy11061031 ◽

2021 ◽

Vol 11 (6) ◽

pp. 1031

Author(s):

Maciej Spychalski ◽

Rafal Kukawka ◽

Włodzimierz Krzesiński ◽

Tomasz Spiżewski ◽

Monika Michalecka ◽

...

Keyword(s):

Plant Resistance ◽

Positive Impact ◽

Quality Parameters ◽

Nutritional Composition ◽

Matter Content ◽

Dry Matter Content ◽

Yield And Quality ◽

Amide Derivative ◽

Combined Use ◽

The Impact

Triggering the plant resistance induction phenomenon by chemical compounds, for example acibenzolar-S-methyl ester, has been known and described in scientific literature. Other benzothadiazole derivatives have been also described; however, their properties have not been sufficiently studied. The tested substance, N-methyl-N-methoxyamide-7-carboxybenzo(1.2.3)thiadiazole (BTHWA), is an amide derivative of benzothiadiazole, showing a stimulating effect on plant growth, apart from its plant resistance inducing activity. This article presents the impact of BTHWA, used solo and in the program with fungicides, on the strawberry plants development, fruits health, yield, and quality parameters of the crop. The results show that the combined use of BTHWA and fungicides had a positive impact on the plants health and fruit health and nutraceutical and nutritional composition of compounds when compared to the results obtained when strawberries were treated only with the BTHWA or the fungicide. As a result of BTHWA use, the partitioning of assimilates has changed, which directly translated into the results of the conducted experiments. A reduction in the respiration of the fruit during storage was also observed, possibly due to a reduced disease infestation and a lower dry matter content in the fruit. A correlation between the parameters determined during the experiment was found. The BTHWA mode of action was evidenced to be beneficial to strawberry plants and fruit.

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