scholarly journals Anti-inflammatory constituents of topically applied crude drugs. I. Constituents and anti-inflammatory effect of Eriobotrya japonica Lindl.

1986 ◽  
Vol 34 (6) ◽  
pp. 2614-2617 ◽  
Author(s):  
MINEO SHIMIZU ◽  
HIDEKI FUKUMURA ◽  
HIDEKI TSUJI ◽  
SEIICHI TANAAMI ◽  
TOSHIMITSU HAYASHI ◽  
...  
Keyword(s):  
Eriobotrya Japonica ◽  
Crude Drugs ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti-inflammatory constituents of topically applied crude drugs. III. Constituents and anti-inflammatory effect of paraguayan crude drug "tamanda cuna" (Catasetum barbatum Lindle).

1988 ◽  
Vol 36 (11) ◽  
pp. 4447-4452 ◽  
Author(s):  
MINEO SHIMIZU ◽  
HISASHI SHOGAWA ◽  
TOSHIMITSU HAYASHI ◽  
MUNEHISA ARISAWA ◽  
SHOICHI SUZUKI ◽  
...  
Keyword(s):  
Crude Drug ◽  
Crude Drugs ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti-inflammatory constituents of topically applied crude drugs. II. Constituents and anti-inflammatory effect of Cryptomeria japonica D. DON.

1988 ◽  
Vol 36 (10) ◽  
pp. 3967-3973 ◽  
Author(s):  
MINEO SHIMIZU ◽  
HIDEKI TSUJI ◽  
HISASHI SHOGAWA ◽  
HIDEKI FUKUMURA ◽  
SEIICHI TANAAMI ◽  
...  
Keyword(s):  
Cryptomeria Japonica ◽  
Crude Drugs ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti-inflammatory constituents of topically applied crude drugs. IV. Constituents and anti-inflammatory effect of Paraguayan crude drug "Alhucema"(Lavandula latifolia Vill.).

1990 ◽  
Vol 38 (8) ◽  
pp. 2283-2284 ◽  
Author(s):  
Mineo SHIMIZU ◽  
Hisashi SHOGAWA ◽  
Takayasu MATSUZAWA ◽  
Sakiko YONEZAWA ◽  
Toshimitsu HAYASHI ◽  
...  
Keyword(s):  
Crude Drug ◽  
Crude Drugs ◽  
Anti Inflammatory ◽  
Lavandula Latifolia ◽  
Inflammatory Effect

The Pharmacological and Pathological Studies on Taiwan Folk Medicine (VII): The Anti-inflammatory Effect of Echinops grjiisii

1992 ◽  
Vol 20 (02) ◽  
pp. 127-134 ◽  
Author(s):  
Chun-Ching Lin ◽  
Cheng-hung Lin ◽  
Hui-Fen Chiu ◽  
Min-Fu Hu
Keyword(s):  
Methanolic Extract ◽  
Folk Medicine ◽  
Animal Experiments ◽  
Active Principle ◽  
Chloroform Fraction ◽  
Protective Effects ◽  
Active Components ◽  
Crude Drugs ◽  
Anti Inflammatory ◽  
Inflammatory Effect

The hepatotoxic-protective effects of "San-fang-feng" (the root of E. grijisii) and "Lou-lu" (the root of E. latifolius) on CCl 4 induced hepatotoxicity have been proposed in our previous paper (Lin et al, 1990). The anti-inflammatory effects of these two crude drugs were investigated in this experiment. The results indicated that both of them displayed pronounced anti-inflammatory activities against carrageenan-induced edema. Furthermore, in order to isolated the main active components of E. grijisii, fractions obtained from the methanolic extract of E. grijisii were investigated in mice for their 24-h LD 50 and 95% confidence limits, which could be used as a guiding for further animal experiments. Our findings demonstrated that n-hexane (100,300 mg/kg), chloroform (30,100,300 mg/kg) and ethyl acetate (30,100, 300 mg/kg) fractions could markedly inhibit the carrageenan-induced inflammation, and the main active principle was found to be concentrated in the chloroform fraction, which possessed significant inhibitory activities even more than does indomethacin.

Anti-inflammatory Effect of Triterpenoic Acids of Eriobotrya japonica (Thunb.) Lindl. Leaf on Rat Model of Chronic Bronchitis

2009 ◽  
Vol 37 (02) ◽  
pp. 309-321 ◽  
Author(s):  
Jin-Fang Ge ◽  
Ting-Yu Wang ◽  
Bin Zhao ◽  
Xiong-Wen Lv ◽  
Yong Jin ◽  
...  
Keyword(s):  
Chronic Bronchitis ◽  
Bronchial Epithelium ◽  
Lung Homogenate ◽  
Eriobotrya Japonica ◽  
Intercellular Adhesion Molecule ◽  
Enzyme Linked Immunosorbent Assay ◽  
Necrosis Factor Alpha ◽  
Tnf Α ◽  
Anti Inflammatory ◽  
Inflammatory Effect

This study was designed to investigate the anti-inflammatory effect of Triterpenoic Acids from Eriobotrya japonica (Thunb.) Lindl. (TAL) on chronic bronchitis (CB) in rats. CB model was established by combination of Bacillus Calmette-Guerin (BCG, 5 mg/kg, injected through the caudal vein) and lipopolysaccharide (LPS, 1 g/L, injected through endotracheal intubation). Rats with CB model were treated with TAL (50, 150 and 450 mg/kg) for 3 weeks. The leukocytes in bronchoalveolar lavage fluid (BALF) were counted after Wright staining, the levels of cytokine tumor necrosis factor alpha (TNF-α), interleukin (IL)-8, and IL-10 in the supernatants of lung homogenate were assessed by enzyme-linked immunosorbent assay (ELISA), and the protein expression of nuclear factor kappaB (NF-κB) and intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelium were tested by immunohistochemical staining. As compared to the normal and sham groups, the total number of leukocyte, the differential counts of neutrophils and alveolar macrophage (AM) in BALF, the levels of TNF-α and IL-8 in the supernatants of lung homogenate, and the expression of NF-κB and ICAM-1 on bronchial epithelium in CB rats were significantly increased, while the level of IL-10 was decreased. TAL (50, 150 and 450 mg/kg) attenuated these alterations in model CB rats, which indicates that TAL has anti-inflammatory effect in the rats with CB.

Reduction of paw edema and liver oxidative stress in carrageenan-induced acute inflammation by Lobaria pulmonaria and Parmelia caperata, lichen species, in mice

2019 ◽  
pp. 1-9
Author(s):  
Samira Salem ◽  
Essaid Leghouchi ◽  
Rachid Soulimani ◽  
Jaouad Bouayed
Keyword(s):  
Time Course ◽  
Acute Inflammation ◽  
Lichen Species ◽  
Paw Edema ◽  
Sod Activity ◽  
Edema Formation ◽  
Lobaria Pulmonaria ◽  
Anti Inflammatory ◽  
Endogenous Antioxidant ◽  
Inflammatory Effect

Abstract. Paw edema volume reduction is a useful marker in determining the anti-inflammatory effect of drugs and plant extracts in carrageenan-induced acute inflammation. In this study, the anti-inflammatory effect of Lobaria pulmonaria (LP) and Parmelia caperata (PC), two lichen species, was examined in carrageenan-induced mouse paw edema test. Compared to the controls in carrageenan-induced inflammation (n = 5/group), our results showed that pretreatment by single oral doses with PC extract (50–500 mg/kg) gives better results than LP extract (50–500 mg/kg) in terms of anti-edematous activity, as after 4 h of carrageenan subplantar injection, paw edema formation was inhibited at 82–99% by PC while at 35–49% by LP. The higher anti-inflammatory effect of PC, at all doses, was also observed on the time-course of carrageenan-induced paw edema, displaying profile closely similar to that obtained with diclofenac (25 mg/kg), an anti-inflammatory drug reference (all p < 0.001). Both LP and PC, at all doses, significantly ameliorated liver catalase (CAT) activity (all p < 0.05). However, superoxide dismutase (SOD) activity, glutathione peroxidase (GPx) activity and glutathione (GSH) levels were found increased in liver of PC- compared to LP-carrageenan-injected mice. Our findings demonstrated on one hand higher preventive effects of PC compared to LP in a mouse carrageenan-induced inflammatory model and suggested, on the other hand, that anti-inflammatory effects elicited by the two lichens were closely associated with the amelioration in the endogenous antioxidant status of liver.

Anti-inflammatory effect of Curcuma longa (turmeric) rhizome when administered topically in gel form

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
AH Mollik ◽  
W Mozammel Haq ◽  
S Chandra Bachar ◽  
R Jahan ◽  
M Rahmatullah
Keyword(s):  
Curcuma Longa ◽  
Anti Inflammatory ◽  
Inflammatory Effect
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