scholarly journals Meldrum's acid in organic synthesis. V. Versatile one-pot synthesis of indolepropionic esters via simultaneous condensation of three different carbon components, indole, aldehydes and Meldrum's acid.

1982 ◽  
Vol 30 (9) ◽  
pp. 3092-3096 ◽  
Author(s):  
YUJI OIKAWA ◽  
HITOSHI HIRASAWA ◽  
OSAMU YONEMITSU
Keyword(s):  
Organic Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis

Meldrum's acid in organic synthesis. 1. A convenient one-pot synthesis of ethyl indolepropionates

1978 ◽  
Vol 19 (20) ◽  
pp. 1759-1762 ◽  
Author(s):  
Yuji Oikawa ◽  
Hitoshi Hirasawa ◽  
Osamu Yonemitsu
Keyword(s):  
Organic Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis

An Expeditious One-Pot Three-Component Synthesis of 4-Aryl-3,4-dihydrobenzo[g] quinoline-2,5,10(1H)-triones under Green Conditions

2020 ◽  
Vol 23 (23) ◽  
pp. 2626-2634
Author(s):  
Saiedeh Kamalifar ◽  
Hamzeh Kiyani
Keyword(s):  
Reaction Medium ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
First Time ◽  
Green Conditions

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.

One Pot Synthesis of Monoalkylated and Mixed, Dialkylated Meldrum's Acid Derivatives

2004 ◽  
Vol 34 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Uday V. Desai ◽  
D. M. Pore ◽  
R. B. Mane ◽  
S. B. Solabannavar ◽  
P. P. Wadgaonkar
Keyword(s):  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Meldrum's Acid Derivatives

The Reaction of Alkyl Isocyanides and Benzylidene Meldrum's Acid Derivatives in the presence of Water: A One-Pot synthesis of 4-(Alkylamino)-3-Aryl-4-Oxobutanoic Acids

2002 ◽  
Vol 2002 (9) ◽  
pp. 433-435 ◽  
Author(s):  
Ahmad Shaabani ◽  
Mohammad Bagher Teimouri
Keyword(s):  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Alkyl Isocyanides ◽  
Meldrum's Acid Derivatives

The reaction between alkyl isocyanides and substituted-benzylidene Meldrum's acid derivatives in the presence of water produces 4-(alkylamino)-3-aryl-4-oxobutanoic acids in good yields.

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