scholarly journals Effect of Basic Cupric Acetate on the Biochemical Changes in the Liver of the Rat Fed Carcinogenic Aminoazo Dye. II. Activity and Isozyme Pattern of Lactate Dehydrogenase

1970 ◽  
Vol 18 (5) ◽  
pp. 1050-1052 ◽  
Author(s):  
YASUHIRO YAMANE ◽  
KAZUO SAKAI ◽  
MIYOKO HAYASHI ◽  
MIDORI MATSUZAKI ◽  
AKIRA HANAKI
Keyword(s):  
Lactate Dehydrogenase ◽  
Isozyme Pattern ◽  
Biochemical Changes ◽  
Cupric Acetate

scholarly journals THE DISTRIBUTION OF LACTATE DEHYDROGENASE ISOZYMES IN HUMAN SKELETAL MUSCLE FIBERS

1964 ◽  
Vol 12 (8) ◽  
pp. 608-614 ◽  
Author(s):  
M. VAN WIJHE ◽  
M. C. BLANCHAER ◽  
S. ST. GEORGE-STUBBS
Keyword(s):  
Skeletal Muscle ◽  
Lactate Dehydrogenase ◽  
Human Skeletal Muscle ◽  
Muscle Fibers ◽  
Isozyme Pattern ◽  
Electrophoretic Separation ◽  
Lactate Dehydrogenase Isozymes ◽  
Dehydrogenase Isozyme ◽  
Lactate Dehydrogenase Isozyme ◽  
Normal Human

A study of the distribution of lactate dehydrogenase isozymes in single fibers from normal human skeletal muscle is presented. The fibers were classified into red, intermediate and white types on histochemical grounds and their lactate dehydrogenase isozyme content assessed by electrophoretic separation in veronal buffered agar. The results generally agreed with previous homogenate studies on animal skeletal muscle, in that the white fibers contained almost exclusively isozymes IV and V, whereas red fibers were rich in isozymes I, II and III, but IV and V also appeared indigenous to these fibers. The intermediate fibers had an isozyme pattern combining the features of red and white fibers. The metabolic implications of these findings are discussed.

scholarly journals DEVELOPMENTAL CHANGE AND REGIONAL DIFFERENCE OF THE LACTATE DEHYDROGENASE ISOZYME PATTERN IN RAT BRAIN

1980 ◽  
Vol 13 (2) ◽  
pp. 164-172
Author(s):  
KANKATSU YUN ◽  
TAKESHI MATSUO ◽  
TAKASHI ORIBE ◽  
TSUTOMU TOMIOKA ◽  
TAKAYOSHI IKEDA
Keyword(s):  
Lactate Dehydrogenase ◽  
Rat Brain ◽  
Regional Difference ◽  
Developmental Change ◽  
Isozyme Pattern ◽  
Dehydrogenase Isozyme ◽  
Lactate Dehydrogenase Isozyme

scholarly journals Biochemical Effects to Toxicity of CCl4 on Rosy Barbs (Puntius conchonius)

Our Nature ◽  
1970 ◽  
Vol 3 (1) ◽  
pp. 20-25 ◽  
Author(s):  
H. Bhattacharya ◽  
L. Lun ◽  
G.D. Gomez R.
Keyword(s):  
Alkaline Phosphatase ◽  
Lactate Dehydrogenase ◽  
Enzymatic Activity ◽  
Blood Urea Nitrogen ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Target Organ ◽  
Biochemical Changes ◽  
Urea Nitrogen ◽  
Biochemical Effects

Biochemical changes in the liver, kidneys and gills of rosy barbs due to toxicity of CCl4 were measured after 96 hour exposure. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), blood urea nitrogen (BUN) and creatinin (CRN), levels were measured. Significant increase in ALP, ALT, LDH and BUN activities were observed in the liver in the treated groups compared to controls (P < 0.05). AST level was significantly higher in the kidneys. This study indicates that the enzymatic activity was comparatively higher in the liver than kidneys or gills, suggesting that the liver is the target organ of CCL4 toxicity to rosy barbs.Keywords: Toxicity, Rosy Barb, CCl4doi:10.3126/on.v3i1.330Our Nature (2005)5:20-25

THE ACTIVITY OF LACTATE DEHYDROGENASE ISOZYMES DURING THYROXINE-INDUCED TADPOLE METAMORPHOSIS

1966 ◽  
Vol 44 (3) ◽  
pp. 303-310 ◽  
Author(s):  
H. C. Kim ◽  
A. D'Iorio ◽  
W. K. Paik
Keyword(s):  
Lactate Dehydrogenase ◽  
Isozyme Pattern ◽  
Improved Method ◽  
Lactate Dehydrogenase Isozymes ◽  
Ldh Activity ◽  
Thyroxine Treatment ◽  
Tadpole Tail ◽  
Ldh Isozymes

A new improved method to quantitate the amount of the isozymes of lactate dehydrogenase (LDH) has been devised. The method is sensitive and very reproducible. This method has been employed for studies on LDH isozymes during thyroxine-induced tadpole metamorphosis. Only one isozyme is present in tadpole liver whereas three isozymes are present in tadpole tail and brain. Thyroxine treatment produced a decrease of the total LDH activity of tadpole liver, tail, and brain; however, the relative amount of the isozyme F3 in tail and brain is the only fraction which shows a decrease. The F1 and F2 fractions show an increase in relative amount. Thalidomide has no influence on the isozyme pattern of LDH in thyroxine-induced metamorphosis of the tadpole.

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