scholarly journals The Effect of Penetration Enhancers on Permeation Kinetics of Nitrendipine in Two Different Skin Models

2008 ◽  
Vol 31 (9) ◽  
pp. 1766-1772 ◽  
Author(s):  
Ashu Mittal ◽  
Udai Vir Singh Sara ◽  
Asgar Ali ◽  
Mohammed Aqil
Keyword(s):  
Penetration Enhancers ◽  
Kinetics Of ◽  
Permeation Kinetics

Differences In Permeation Kinetics of Cryoprotective Solutions In Equine Oocytes Compared To That In Ovarian Tissue

Cryobiology ◽  
2021 ◽  
Vol 103 ◽  
pp. 186
Author(s):  
Harriëtte Oldenhof ◽  
Jürgen Lotz ◽  
Sercan Içli ◽  
Dejia Liu ◽  
Sükrü Caliskan ◽  
...  
Keyword(s):  
Ovarian Tissue ◽  
Kinetics Of ◽  
Permeation Kinetics

Effect of enhancers on permeation kinetics of captopril for transdermal system

2008 ◽  
Vol 2 (1) ◽  
pp. 35 ◽  
Author(s):  
BM Dinesh ◽  
BG Desai ◽  
AR Annamalai ◽  
B Divya
Keyword(s):  
Kinetics Of ◽  
Permeation Kinetics

scholarly journals Freezing Weakens the Barrier Function of Reconstructed Human Epidermis as Evidenced by Raman Spectroscopy and Percutaneous Permeation

Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1041
Author(s):  
Yuri Dancik ◽  
Hichem Kichou ◽  
Christophe Eklouh-Molinier ◽  
Martin Soucé ◽  
Emilie Munnier ◽  
...  
Keyword(s):  
Barrier Function ◽  
Principal Component ◽  
Human Epidermis ◽  
Animal Tissues ◽  
Reconstructed Human Epidermis ◽  
Percutaneous Permeation ◽  
Time Required ◽  
Kinetics Of ◽  
Permeation Kinetics

The development and characterization of reconstructed human epidermis (RHE) is an active area of R&D. RHE can replace animal tissues in pharmaceutical, toxicological and cosmetic sciences, yielding scientific and ethical advantages. RHEs remain costly, however, due to consumables and time required for their culture and a short shelf-life. Storing, i.e., freezing RHE could help reduce costs but to date, little is known on the effects of freezing on the barrier function of RHE. We studied such effects using commercial EpiSkin™ RHE stored at −20, −80 and −150 °C for 1 and 10 weeks. We acquired intrinsic Raman spectra in the stratum corneum (SC) of the RHEs as well as spectra obtained following topical application of resorcinol in an aqueous solution. In parallel, we quantified the effects of freezing on the permeation kinetics of resorcinol from time-dependent permeation experiments. Principal component analyses discriminated the intrinsic SC spectra and the spectra of resorcinol-containing RHEs, in each case on the basis of the freezing conditions. Permeation of resorcinol through the frozen RHE increased 3- to 6-fold compared to fresh RHE, with the strongest effect obtained from freezing at −20 °C for 10 weeks. Due to the extensive optimization and standardization of EpiSkin™ RHE, the effects observed in our work may be expected to be more pronounced with other RHEs.

Temperature‐dependent mucosal permeation kinetics of stigmasterol microspheres: In vivo mice model antioral candidiasis study

2020 ◽  
Vol 108 (4) ◽  
pp. 1636-1654
Author(s):  
Partha Niyogi ◽  
Snigdha Pattnaik ◽  
Laxmidhar Maharana ◽  
Rajaram Mohapatra ◽  
Saikat Haldar
Keyword(s):  
Mice Model ◽  
Temperature Dependent ◽  
Kinetics Of ◽  
Permeation Kinetics

Analysis of steady state and non-steady state corneal permeation of diclofenac

RSC Advances ◽  
2016 ◽  
Vol 6 (38) ◽  
pp. 31976-31987 ◽  
Author(s):  
Rajaram Mohapatra ◽  
Subrata Mallick ◽  
Ashirbad Nanda ◽  
Rudra N. Sahoo ◽  
Arunima Pramanik ◽  
...  
Keyword(s):  
Steady State ◽  
Statistical Moment ◽  
Moment Theory ◽  
Corneal Permeation ◽  
Kinetics Of ◽  
Permeation Kinetics

The present study was undertaken for characterization of the steady state and non steady state corneal permeation kinetics of diclofenac potassium (DCP) using statistical moment theory.

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