scholarly journals Optimization of Suppository Preparation Containing Sodium Laurate and Taurine That Can Safely Improve Rectal Absorption of Rebamipide

2006 ◽  
Vol 29 (2) ◽  
pp. 330-335 ◽  
Author(s):  
Masateru Miyake ◽  
Takanori Minami ◽  
Yoshikazu Oka ◽  
Naoki Kamada ◽  
Hiroyuki Yamazaki ◽  
...  
Keyword(s):  
Sodium Laurate ◽  
Rectal Absorption

Development of suppository formulation safely improving rectal absorption of rebamipide, a poorly absorbable drug, by utilizing sodium laurate and taurine

2004 ◽  
Vol 99 (1) ◽  
pp. 63-71 ◽  
Author(s):  
Masateru Miyake ◽  
Naoki Kamada ◽  
Yoshikazu Oka ◽  
Tadashi Mukai ◽  
Takanori Minami ◽  
...  
Keyword(s):  
Sodium Laurate ◽  
Rectal Absorption

A fourier transform infrared study of the coagel to micelle transitions of sodium laurate and sodium oleate

1982 ◽  
Vol 4 (2) ◽  
pp. 131-145 ◽  
Author(s):  
David G. Cameron ◽  
Junzo Umemura ◽  
Patrick T.T. Wong ◽  
Henry H. Mantsch
Keyword(s):  
Fourier Transform ◽  
Sodium Oleate ◽  
Fourier Transform Infrared ◽  
Sodium Laurate ◽  
Infrared Study

scholarly journals Release and Rectal Absorption of Aminophylline Suppositories Prepared in Hospital Pharmacy

1979 ◽  
Vol 5 (3) ◽  
pp. 155-161 ◽  
Author(s):  
TADAO FUJII ◽  
AKIE KUBOTA ◽  
NORIKO MIZUSHIMA
Keyword(s):  
Hospital Pharmacy ◽  
Rectal Absorption

Rectal absorption enhancement of insulin in rabbits from hollow-type suppositories by glyceryl-1-monooctanoate

1990 ◽  
Vol 13 (2-3) ◽  
pp. 316-317 ◽  
Author(s):  
Y. Watanabe ◽  
Y. Matsumoto ◽  
N. Hori ◽  
M. Matsumoto
Keyword(s):  
Absorption Enhancement ◽  
Rectal Absorption

Excretion in the house cricket: stimulation of rectal reabsorption by homogenates of the corpus cardiacum

1993 ◽  
Vol 185 (1) ◽  
pp. 305-323 ◽  
Author(s):  
J. H. Spring ◽  
S. A. Albarwani
Keyword(s):  
Time Course ◽  
Chloride Transport ◽  
Malpighian Tubule ◽  
Acheta Domesticus ◽  
Rectal Absorption ◽  
K Uptake ◽  
House Cricket ◽  
Tubule Fluid ◽  
Stimulation Of

1. We describe an in vitro perfused preparation of Acheta domesticus rectum which allows direct comparison of Malpighian tubule secretion and rectal absorption under identical conditions. Rectal absorption is stimulated four- to sixfold by corpora cardiaca (CC) homogenates and the stimulated rate is sufficiently rapid to account for all the fluid secreted by the tubules. 2. The time course for increased fluid absorption is similar to that required to stimulate electrogenic chloride transport in locusts and grasshoppers. Chloride is rapidly absorbed by the rectum under all conditions, along with lesser amounts of Na+ and K+. Unlike the situation in locusts, K+ uptake is unaffected by CC homogenates and the stimulated absorbate is NaCl-rich, similar in composition to the NaCl-rich tubule fluid produced under stimulated conditions. The absorbate is always slightly hypo-osmotic to the perfusate, reaching a maximum differential of approximately 15 mosmol l-1 following CC stimulation. 3. The antidiuretic factor that reduces tubule secretion does not promote fluid reabsorption by the rectum.

Integration Traditional Chinese Medicine and Nibble Debridement and Dressing Method Reduce Thrombosis and Inflammatory Response in the Treatment of Thromboangiitis Obliterans

2020 ◽  
Author(s):  
Jianhua Li ◽  
Jingfeng Zhong ◽  
Chunfa Huang ◽  
Jiewen Guo ◽  
Arong Li
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Rat Model ◽  
Inflammatory Cell ◽  
Blood Rheology ◽  
Arterial Disease ◽  
Sodium Laurate ◽  
Thromboangiitis Obliterans ◽  
Dressing Method ◽  
Masson Staining

Abstract Background: Thromboangiitis obliterans (TAO), also known as Buerger's disease, is an occlusive arterial disease. However, the pathogenesis of TAO is still unclear. Research has shown that traditional Chinese medicine (TCM) has significant advantages in the treatment of TAO. Our purpose is to explore the underlying roles of TCM in combination with nibble debridement and dressing method (NDDM) in TAO rat model.Methods: 10 mg/ml sodium laurate was utilized to establish a TAO rat model, and then the TAO mode rats were treated with notoginseng powder (NP), maifusheng (MFS) or the combination of NP or MFS and NDDM. Ganrene’s classification and, blood rheology was evaluated; the pathological characteristics of rat limbs were examined by H&E staining and Masson staining; CD3+ and CD20+ levels were measured by immunohistochemistry and flow cytometry. In addition, inflammation-associated cytokines were analyzed by RT-qPCR, Western blot and ELISA assays. Results: ntegration NP or MFS and NDDM dramatically reduced the ganrene’s classification and affected blood rheology parameter of TAO model rats compared with NP and MFS alone. Meanwhile, NP or MFS in combination with NDDM decreased CD3+CD20+T cells, reduced thrombosis and inflammatory cell infiltration, and dramatically decreased the levels of inflammation-associated cytokines.Conclusion: Our results suggested that integration NP or MFS and NDDM could relieve the symptoms of TAO model rats induced by sodium laurate, which might provide new management strategy for TAO.

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