scholarly journals Amino Acids and Peptides. XXIX. Synthesis and Antimetastatic Effects of Peptides and Peptide-Poly(Ethylene Glycol) Hybrids Related to the Core Sequence of the Type III Connecting Segment Domain of Fibronectin.

1996 ◽  
Vol 19 (12) ◽  
pp. 1574-1579 ◽  
Author(s):  
Koichi KAWASAKI ◽  
Mitsuko MAEDA ◽  
Sachiye INOUE ◽  
Yuko YAMASHIRO ◽  
Yoshihisa KANEDA ◽  
...  
Keyword(s):  
Amino Acids ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Type Iii ◽  
The Core ◽  
Core Sequence ◽  
Poly Ethylene

Water-soluble star polymers with a phthalocyanine as the core and poly(ethylene glycol) chains as branches

2012 ◽  
Vol 126 (4) ◽  
pp. 1359-1368 ◽  
Author(s):  
Placido Mineo ◽  
Rossana Alicata ◽  
Norberto Micali ◽  
Valentina Villari ◽  
Emilio Scamporrino
Keyword(s):  
Ethylene Glycol ◽  
Star Polymers ◽  
Water Soluble ◽  
Poly Ethylene Glycol ◽  
The Core ◽  
Poly Ethylene

Mesoscale Simulation of the Structure of Star Acrylated Poly(ethylene glycol-co-lactide) Hydrogels

2012 ◽  
Vol 1418 ◽  
Author(s):  
Seyed Sina Moeinzadeh ◽  
Esmaiel Jabbari
Keyword(s):  
Ethylene Glycol ◽  
Volume Fraction ◽  
Equations Of Motion ◽  
Dissipative Particle Dynamics ◽  
Random Force ◽  
Dynamics Simulation ◽  
Coarse Grained ◽  
Poly Ethylene Glycol ◽  
The Core ◽  
Poly Ethylene

ABSTRACTIn this work the microstructures of star acrylated poly(ethylene glycol-co-lactide) (SPELA) with different LA:EG ratios in the aqueous solution have been simulated via Dissipative Particle Dynamics (DPD) approach at the mesoscale. The system components were coarse-grained into different beads (set of atoms) which moved according to the Newton’s equations of motion integrated via a modified Velocity-Verlet algorithm. The force acting on each bead, in a specific cutoff distance (rc), was divided into a conservative force (FC), random force (FR), dissipative force (FD), bond force (FS) and bond angle force (FE). The repulsion parameters of the conservative force (αij) were calculated from the solubility parameter of the beads, each of which were extracted from an atomistic molecular dynamics simulation (MD). Simulations showed the formation of micelles with lactide and acrylate beads occupied the core and hydrophilic ethylene oxide segments extending through the water to form the corona. The micelles showed an increasing trend in size and decreasing trend in number density with increase in LA:EG ratio. Results showed that the acrylate density decreased from the center of the micelles to the core surface although the overall amount of acrylates increased due to the increase in volume. Furthermore, the running integration number of acrylate-water beads showed decreasing accessibility of acrylates to water with increasing PLA volume fraction.

scholarly journals Amino Acids and Peptides. XXII. Preparation and Antinociceptive Effect of (D-Ala2)Leu-Enkephalin-Poly(Ethylene Glycol) Hybrid.

1994 ◽  
Vol 17 (6) ◽  
pp. 823-825 ◽  
Author(s):  
Mitsuko MAEDA ◽  
Koichi KAWASAKI ◽  
Tadanori MAYUMI ◽  
Masakatsu TAKAHASHI ◽  
Hiroshi KANETO
Keyword(s):  
Amino Acids ◽  
Ethylene Glycol ◽  
Antinociceptive Effect ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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