scholarly journals Flow Effects on Cultured Vascular Endothelial and Smooth Muscle Cell Functions.

1991 ◽  
Vol 16 (5) ◽  
pp. 365-374 ◽  
Author(s):  
Ohmi Ono ◽  
Joji Ando ◽  
Akira Kamiya ◽  
Yoshinori Kuboki ◽  
Hisakazu Yasuda
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Vascular Endothelial ◽  
Cell Functions ◽  
Flow Effects

An In Vitro Study of Nano-fiber Polymers for Guided Vascular Regeneration

2001 ◽  
Vol 711 ◽  
Author(s):  
Derick C. Miller ◽  
Anil Thapa ◽  
Karen M. Haberstroh ◽  
Thomas J. Webster
Keyword(s):  
Smooth Muscle ◽  
Cell Adhesion ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Surrounding Tissue ◽  
Arterial Smooth Muscle Cell ◽  
Arterial Smooth Muscle ◽  
Cell Functions ◽  
Fiber Dimensions

ABSTRACTBiomaterials that successfully integrate into surrounding tissue should match not only the tissue's mechanical properties, but also the dimensions of the associated nano-structured extra-cellular matrix (ECM) components. The goal of this research was to use these ideals to develop a synthetic, nano-structured, polymeric biomaterial that has cytocompatible and mechanical behaviors similar to that of natural vascular tissue. In a novel manner, poly-lactic acid/polyglycolic acid (PLGA) (50/50 wt.% mix) and polyurethane were separately synthesized to possess a range of fiber dimensions in the micron and nanometer regime. Preliminary results indicated that decreasing fiber diameter on both PLGA and PU enhanced arterial smooth muscle cell adhesion; specifically, arterial smooth muscle cell adhesion increased 23% when PLGA fiber dimensions decreased from 500 to 50 nm and increased 76% on nano-structured, compared to conventional structured, polyurethane. However, nano-structured PLGA decreased endothelial cell adhesion by 52%, whereas adhesion of these same cells was increased by 50% on polyurethane. For these reasons, the present in vitro study provides the first evidence that polymer fiber dimensions can be used to selectively control cell functions for vascular prosthesis.

Functional role of miRNA-34A in smooth muscle cell functions and neointima formation

2016 ◽  
Vol 244 ◽  
pp. e3-e4 ◽  
Author(s):  
F. Yang ◽  
Q. Chen ◽  
G. Wen ◽  
C. Zhang ◽  
L.A. Luong ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Functional Role ◽  
Neointima Formation ◽  
Cell Functions

Vascular Endothelial and Smooth Muscle Cell Culture on NaOH-Treated Poly(ɛ-caprolactone) Films: A Preliminary Study for Vascular Graft Development

2005 ◽  
Vol 5 (5) ◽  
pp. 415-423 ◽  
Author(s):  
María Concepción Serrano ◽  
María Teresa Portolés ◽  
María Vallet-Regí ◽  
Isabel Izquierdo ◽  
Lorenzo Galletti ◽  
...  
Keyword(s):  
Cell Culture ◽  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Vascular Graft ◽  
Vascular Endothelial ◽  
Muscle Cell Culture ◽  
Smooth Muscle Cell Culture ◽  
Preliminary Study

701 Evaluation of endothelial and smooth muscle cell functions toward ultra-early diagnosis of atherosclerosis

2012 ◽  
Vol 2012.61 (0) ◽  
pp. _701-1_-_701-2_
Author(s):  
Toshiyuki YAGUCHI ◽  
Kenji SHIMO ◽  
Takahiro KUROKAWA ◽  
Kazuaki NAGAYAMA ◽  
Hiromasa TSUKAHARA ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Early Diagnosis ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Cell Functions
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