scholarly journals Role of superoxide radicals in cytotoxic effects of Fe-NTA on cultured normal liver epithelial cells.

1987 ◽  
Vol 12 (5) ◽  
pp. 407-420 ◽  
Author(s):  
Masayasu Yamada ◽  
Tohru Okigaki ◽  
Michiyasu Awai
Keyword(s):  
Epithelial Cells ◽  
Normal Liver ◽  
Superoxide Radicals ◽  
Cytotoxic Effects ◽  
Liver Epithelial Cells

Cytotoxic effects of cadmium in mammary epithelial cells: Protective role of the macrocycle [15]pyN5

2012 ◽  
Vol 50 (6) ◽  
pp. 2180-2187 ◽  
Author(s):  
Sandrina Gonçalves ◽  
Ana Sofia Fernandes ◽  
Nuno G. Oliveira ◽  
Joana Marques ◽  
Judite Costa ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Mammary Epithelial Cells ◽  
Protective Role ◽  
Mammary Epithelial ◽  
Cytotoxic Effects

scholarly journals Role of phospholipase A2 in the cytotoxic effects of oxalate in cultured renal epithelial cells

1999 ◽  
Vol 56 (4) ◽  
pp. 1432-1441 ◽  
Author(s):  
Yasuo Kohjimoto ◽  
Lori Kennington ◽  
Cheryl R. Scheid ◽  
Thomas W. Honeyman
Keyword(s):  
Epithelial Cells ◽  
Phospholipase A2 ◽  
Cytotoxic Effects ◽  
Renal Epithelial Cells

scholarly journals Cytotoxic Action of Serratia marcescens Hemolysin on Human Epithelial Cells

1999 ◽  
Vol 67 (2) ◽  
pp. 817-825 ◽  
Author(s):  
Ralf Hertle ◽  
Martina Hilger ◽  
Sandra Weingardt-Kocher ◽  
Iwan Walev
Keyword(s):  
Epithelial Cells ◽  
Serratia Marcescens ◽  
Lipid Membranes ◽  
Trypan Blue ◽  
Cytotoxic Action ◽  
Cytotoxic Effects ◽  
Atp Level ◽  
Vacuole Formation ◽  
Human Epithelial Cells

ABSTRACT Incubation of human epithelial cells with nanomolar concentrations of chromatographically purified Serratia marcescenshemolysin (ShlA) caused irreversible vacuolation and subsequent lysis of the cells. Vacuolation differed from vacuole formation byHelicobacter pylori VacA. Sublytic doses of ShlA led to a reversible depletion of intracellular ATP. Restoration to the initial ATP level was presumably due to the repair of the toxin damage and was inhibited by cycloheximide. Pores formed in epithelial cells and fibroblasts without disruption of the plasma membrane, and the pores appeared to be considerably smaller than those observed in artificial lipid membranes and in erythrocytes and did not allow the influx of propidium iodide or trypan blue. All cytotoxic effects induced by isolated recombinant ShlA were also obtained with exponentially growingS. marcescens cells. The previously suggested role of the hemolysin in the pathogenicity of S. marcescens is supported by these data.

scholarly journals Phenotype reversion in fetal human liver epithelial cells identifies the role of an intermediate meso-endodermal stage before hepatic maturation

2008 ◽  
Vol 121 (7) ◽  
pp. 1002-1013 ◽  
Author(s):  
M. Inada ◽  
A. Follenzi ◽  
K. Cheng ◽  
M. Surana ◽  
B. Joseph ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Human Liver ◽  
Liver Epithelial Cells

The Presence and Role of Transmembrane Transforming Growth Factor-α in Cultures of Rat Liver Epithelial Cells

1995 ◽  
Vol 218 (2) ◽  
pp. 573-576 ◽  
Author(s):  
Christine Heberden ◽  
Thierry Mercier ◽  
Isabelle Gaillard-Sanchez ◽  
Brigitte Huet ◽  
Paule Martel
Keyword(s):  
Growth Factor ◽  
Epithelial Cells ◽  
Rat Liver ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Α ◽  
Liver Epithelial Cells ◽  
Rat Liver Epithelial Cells ◽  
Factor Α

Effect of Calcium on the Growth and Differentiation of Cultured Rat Esophageal Epithelial Cells

1982 ◽  
Vol 40 ◽  
pp. 132-133
Author(s):  
W.T. Gunning ◽  
M.R. Marino ◽  
M.S. Babcock ◽  
G.D. Stoner
Keyword(s):  
Epithelial Cells ◽  
Cell Types ◽  
Replication Rate ◽  
Enzymatic Dissociation ◽  
Growth Assay ◽  
Epidermal Growth ◽  
Fetal Bovine ◽  
Esophageal Epithelial Cells ◽  
Cellular Replication

The role of calcium in modulating cellular replication and differentiation has been described for various cell types. In the present study, the effects of Ca++ on the growth and differentiation of cultured rat esophageal epithelial cells was investigated.Epithelial cells were isolated from esophagi taken from 8 week-old male CDF rats by the enzymatic dissociation method of Kaighn. The cells were cultured in PFMR-4 medium supplemented with 0.25 mg/ml dialyzed fetal bovine serum, 5 ng/ml epidermal growth factor, 10-6 M hydrocortisone 10-6 M phosphoethanolamine, 10-6 M ethanolamine, 5 pg/ml insulin, 5 ng/ml transferrin, 10 ng/ml cholera toxin and 50 ng/ml garamycin at 36.5°C in a humidified atmosphere of 3% CO2 in air. At weekly intervals, the cells were subcultured with a solution containing 1% polyvinylpyrrolidone, 0.01% EGTA, and 0.05% trypsin. After various passages, the replication rate of the cells in PFMR-4 medium containing from 10-6 M to 10-3 M Ca++ was determined using a clonal growth assay.

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