Facile Synthesis of Self-aggregative Zinc Bacteriochlorins by Modifying Naturally Occurring Chlorophyll-a

2007 ◽  
Vol 36 (7) ◽  
pp. 936-937 ◽  
Author(s):  
Michio Kunieda ◽  
Kohei Yamamoto ◽  
Shin-ichi Sasaki ◽  
Hitoshi Tamiaki
Keyword(s):  
Chlorophyll A ◽  
Facile Synthesis ◽  
Naturally Occurring

A facile synthesis of naturally occurring binaphthoquinones: efficient oxidative dimerization of 4-alkoxy-1-naphthols using silver(II) oxide–40% nitric acid

Tetrahedron ◽  
2002 ◽  
Vol 58 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Yasuhiro Tanoue ◽  
Kazunori Sakata ◽  
Mamoru Hashimoto ◽  
Shin-ich Morishita ◽  
Moritsugu Hamada ◽  
...  
Keyword(s):  
Nitric Acid ◽  
Oxidative Dimerization ◽  
Facile Synthesis ◽  
Naturally Occurring

Phototoxic effects of pyropheophorbide-a from chlorophyll-a on cervical cancer cells

2014 ◽  
Vol 18 (03) ◽  
pp. 182-187 ◽  
Author(s):  
Pankaj Kumar Chaturvedi ◽  
Yong-Wan Kim ◽  
Sang Soo Kim ◽  
Woong Shick Ahn
Keyword(s):  
Cell Line ◽  
Chlorophyll A ◽  
Palliative Treatment ◽  
Caski Cell ◽  
Blue Green Algae ◽  
Naturally Occurring ◽  
Caski Cell Line ◽  
Cervical Cancer Cells ◽  
Pyropheophorbide A

Photodynamic therapy (PDT) is a promising modality in both the curative and palliative treatment against a variety of experimental and naturally occurring human cancers. At present, chlorophyll a derivatives are extensively used for the synthesis of photosensitizers (PSs) for PDT of tumors. In the present study, chlorophyll-a was extracted from the blue-green algae Spirulina platensis by refluxing with acetone. The extract was further acid treated to obtain methylpheophorbide-a (MPa), which was then refluxed in collidine and methylpyropheophorbide-a (Mppa) was obtained. After that, Mppa was converted to pyropheophorbide-a (Ppa) by treatment with 50% sulfuric acid. Finally, phototoxicity and dark toxicity of purified Ppa in two different cell lines, TC-1 and CaSki, were examined by MTT assay. The results suggest that Ppa is more toxic to TC-1 cell line than CaSki cell line. In vivo, the photosensitizing efficiency of Ppa was also higher than those of unloaded PS. These results indicate the potential of Ppa in PDT.

Facile synthesis of new oxalate dimers of naturally occurring 3-hydroxysteroids

2006 ◽  
Vol 42 (5) ◽  
pp. 549-552 ◽  
Author(s):  
L. Nahar ◽  
S. D. Sarker ◽  
A. B. Turner
Keyword(s):  
Facile Synthesis ◽  
Naturally Occurring

ChemInform Abstract: A Facile Synthesis of Naturally Occurring Aminopeptidase Inhibitor Tyromycin A.

ChemInform ◽  
2010 ◽  
Vol 32 (48) ◽  
pp. no-no
Author(s):  
Sivaprakasam Mangaleswaran ◽  
Narshinha P. Argade
Keyword(s):  
Facile Synthesis ◽  
Naturally Occurring

Characterisation of naturally occurring steryl esters derived from Chlorophyll a

1993 ◽  
Vol 34 (18) ◽  
pp. 2989-2992 ◽  
Author(s):  
Gareth E.S. Pearce ◽  
Brendan J. Keely ◽  
Paul J. Harradine ◽  
Christian B. Eckardt ◽  
James R. Maxwell
Keyword(s):  
Chlorophyll A ◽  
Steryl Esters ◽  
Naturally Occurring

ChemInform Abstract: A Facile Synthesis of Naturally Occurring 5-(3-Indolyl)oxazoles.

ChemInform ◽  
2008 ◽  
Vol 39 (20) ◽  
Author(s):  
Dalip Kumar ◽  
Swapna Sundaree ◽  
Gautam Patel ◽  
V. S. Rao
Keyword(s):  
Facile Synthesis ◽  
Naturally Occurring
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