An Efficient Ultrasound-enhanced Controllable Release of Biologically Active Trace Elements on Bioactive Silica-gel-based Material

2006 ◽  
Vol 35 (11) ◽  
pp. 1214-1215 ◽  
Author(s):  
Zhongru Gou ◽  
Wenjian Weng ◽  
Piyi Du ◽  
Gaorong Han
1979 ◽  
Vol 2 (3) ◽  
pp. 151-153 ◽  
Author(s):  
M. Verzele ◽  
M. De Potter ◽  
J. Ghysels
Keyword(s):  

Author(s):  
R. T. Mannapova ◽  
R. R. Shaikhulov ◽  
A. G. Mannapov

It has been established that in propolis, which is a biologically active product of beekeeping contains several dozen compounds, trace elements and vitamins. It contains most of the compounds of flavonoid and terpenoid nature, phytoncides, unsaturated aromatic acids, trace elements: copper, cobalt, potassium, sodium, manganese, zinc, calcium, barium, titanium, nickel, chromium, vanadium, tin, vitamins (A, B, C, E, PP), glucose, fructose, cinnamon alcohol. This composition provides a favorable complex effect of propolis on the body: bactericidal and virusocidal (kills bacteria and viruses), bacteriostatic (slows their growth), regenerative (restoring tissues, heals wounds) and fungicidal (kills fungi). The main therapeutic effect in this biologically active beekeeping product is provided by ferulic, caffeic and benzoic acids, galantine, chrysin, isalpine, pinocebrin. They are combined with trace elements and vitamins, as well as probiotics and prebiotics, which provide the greatest therapeutic effect. This circumstance is important for fungal diseases of poultry and especially for candidiasis. Geese candidiasis has been causing great economic damage to poultry farming all over the world in recent decades. The search for effective prevention measures and therapies remains an unsolved problem to date. The data on the development of reactions basophils, pseudoeosinophils, eosinophils, lymphocytes, monocytes on the background of candidiasis and their enzyme adaptogens: probiotic and propolis for traditional microbiotheria is not effective and does not contribute to the restoration of cytological reactions and meat production of poultry have been presented in the article. At the same time as shown by our studies in farms affected by candidiasis geese timely application of enzyme therapy on a background of immune propolis and propitiatory not only contributes to the full restoration of all biological indicators, but more intense live weight gain of poultry and improve the livability of their livestock. This underlines the importance of taking measures to prevent candidiasis in goose farms, together with good conditions for feeding and housing poultry.


2021 ◽  
Vol 17 (5) ◽  
pp. 418-421
Author(s):  
N.O. Kravchun ◽  
I.P. Dunaeva

Subclinical hypothyroidism is the initial stage of development of hypothyroidism, in which there are no clear clinical symptoms and there is a slow decline in thyroid function. It is known that subclinical hypothyroidism occurs in the population much more often than overt one, its prevalence depends on gender, age of patients and it is much more often diagnosed in elderly women. The literature review considers the effectiveness of the combined herbal preparation to improve the quality of life in hypothyroidism — Endomar, which contains 50 % of Potentilla alba, 25 % of Skutellaria baicalensis and 25 % of Rhodiola rosea. All three components of Endomar are synergistic in hypothyroidism. This multicomponent herbal product has a wide range of therapeutic properties and can be recommended for subclinical forms of thyroid hypofunction. Potentilla alba has been used in medical practice since ancient times. Biologically active components of Potentilla alba extract are flavonoids that regulate the permeability and elasticity of blood vessel walls, thereby neutralizing free radi-cals, phenolcarboxylic acids having antimutagenic and diuretic properties, saponin glycosides, which have a cardiotonic, neurotropic effect, hypocholesterolemic, adaptogenic, sedative action. Rhodiola rosea, an extract of the roots and rhizomes of this plant, is an adaptogen that increases the body’s resistance to stress, exhaustion, fatigue. Rhodiola rosea includes the following active substances: phenols and their derivatives aurol, salidroside; flavonoids: kaempferol, rhodiolin, rhodionin, rhodiosine, trace elements. Endomar includes Skutellaria baicalensis, which has unique properties. This plant contains flavonoid baicalin, which has a neuroprotective and neotropic effect, flavonoids scutellarin and vagonin that maintain normal vascular tone. In general, all components have an antioxidant, antispasmodic, antiinflammatory effect, they are also adaptogens and include trace elements such as magnesium, zinc, selenium.


Author(s):  
V. O. Velichko

Analysis of literature data and the results of our own research show that even with intensive rearing of animals with the use of balanced feeding and keeping them in accordance with the technology - it is almost impossible to avoid stress. And especially, excessive man-made load on agroecosystems also has a negative impact on animal life. Factors that cause a decrease in immune status and the emergence of immune pathology in animals include: industrial technology of animal husbandry, chemicalization in crop and livestock production, man-made pressure, dietary imbalance in nutrients and biologically active substances. This increases the impact on the body of heavy metals, which displace nutrients from body tissues, in particular trace elements and replace them in metabolic processes, which is a potential prerequisite for the development of oxidative stress. The mechanism of development of stress reaction of an organism is closely connected with activity of POL (lipid peroxidation) and depression of antioxidant potential. Under these conditions, the ability of the organism to mobilize protective and adaptive capabilities in response to the action of negative factors becomes especially important. Keeping productive animals in adverse conditions, unbalanced feeding are components of immobilization stress, which reduces their productivity, affects reproductive function, metabolic and functional disorders, reducing nonspecific and specific resistance of the organism (Fedoruk & Kravtsiv, 2003; Velychko, 2008; Velychko, 2011). Under conditions of man-caused load on the environment, respectively, and animals – it is promising to develop effective methods for regulating the activity of the enzymatic system of antioxidant protection with the help of biologically active substances, in particular trace elements. The results of research confirm that this has a positive effect on the formation of productive and adaptive properties of animals. The system of antioxidant protection is a necessary part of non-specific reactions of the organism, a component of the processes of its adaptation to environmental conditions, a component of normal life, a factor in maintaining homeostasis. Widespread immunodeficiency and elucidation of the main links of their pathogenesis have exacerbated the problem of regulating disorders of the immune system. Therefore, knowledge of the patterns of formation of the immune status of animals, especially in the early postnatal period, is important in the development of methods for the correction of immunodeficiency, antioxidant protection.


Author(s):  
O. I. Bodnar ◽  
H. B. Kovalska ◽  
O. Ya. Lukashiv ◽  
V. V. Grubinko

Chlorella is one of the most promising species of algae, which is widely cultivated for the industrial production of nutraceuticals in the form of tablets or powder. The value of Chlorella is primarily due to the high content of proteins and lipids (51–58 % and 20–23 % of dry weight respectively), carotenoids and an almost complete set of vitamins. At the same time, in the process of cultivation, a method was developed to enrich algobiomass and its individual components (primarily the lipid fraction) with selenium, zinc, chromium, as important regulatory trace elements. From chlorella, we obtained seleniumlipid, selenium-zinclipid and selenium-chromiumlipid complexes, and their constancy and structure were grounded by chromatographic and mass spectrometric analysis. After feeding healthy rats with a starch solution of selenium-zinclipid complex (1 ml of which contained 0.4 μg of selenium, 2.5 μg of zinc and 0.5 mg of lipids) and selenium-chromiumlipid complex (1 ml contained 1.85 μg of selenium, 1.1 μg of chromium, 0,45 mg of lipids), no signs of intoxication were found (total medium molecular peptides content was reduced to 1.5 times, the content of TBA-active products and diene conjugates were also decreased), antioxidant processes (increase of glutathione content and activity of glutathione peroxidase while reducing the functional role of catalase) were activated (by increasing of succinate dehydrogenase and cytochrome oxidase activity, glutamate dehydrogenase - the way of glutamate formation), which contributed to the successful functioning of the antioxidant system and maintenance of energy and metabolic homeostasis in the body. The obtained results enable the use of biologically active additives from chlorella, enriched with trace elements Se (IV), Zn (II) and Cr (III), as promising therapeutic and prophylactic substances, which will contribute to the successful functioning of the antioxidant system, maintain energy metabolism and metabolism correction of pathological processes, which is the basis for further studies of the biological activity of the complexes under study.


Plants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2806
Author(s):  
Stanislav Sukhikh ◽  
Lyudmila Asyakina ◽  
Maxim Korobenkov ◽  
Liubov Skrypnik ◽  
Artem Pungin ◽  
...  

Medicinal plants (Cotinus coggygria, Dactylorhiza maculata, Platanthera chlorantha) growing in various territories (Kaliningrad, Moscow, and Minsk regions) were the objects of research. This paper presents a study of the chemical composition of these plants. To analyze the qualitative and quantitative composition of biologically active substances, the method of high-performance liquid chromatography was used. Atomic absorption spectrometry was used to study the content of trace elements. The content of organic acids and vitamins was determined by capillary electrophoresis using the Kapel-105/105M capillary electrophoresis system with high negative polarity. Extracts of medicinal plants were obtained on a Soxhlet apparatus using 70% ethanol as an extractant. It was found that among the biologically active substances in the plants under discussion, hyperoside, rutin (C. coggygria), Ferulic acid and Gallic acid (D. maculata), triene hydrocarbon (3,7-Dimethyl-1,3,6-octatriene), unsaturated alcohol (3,7-Dimethyl-2,6-octadien-1-ol), and benzyl acetate (P. chlorantha) prevailed. Samples of these medicinal plants contained trace elements (phosphorus, potassium, calcium, sodium, magnesium, and sulfur) and many aliphatic organic acids (succinic acid, benzoic acid, fumaric acid, citric acid, oxalic acid, and tartaric acid). The largest amount of biologically active substances and secondary metabolites of the studied plants from the Eastern Baltic is associated with climatic and ecological differences from other regions. The composition of these plants determines the potential of their use in feed additives for livestock and poultry as part of measures to improve the quality of livestock products. The use of medicinal plants for the production of feed additives is relevant in terms of improving regional economies, as well as improving the quality of life and nation’s health by providing ecologically clean livestock products.


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