scholarly journals Threading/Folding Recognition Modes of Phosphodiesters by a p-Nitrophenylamide Cyclodextrin Derivative

2020 ◽  
Vol 49 (5) ◽  
pp. 493-496 ◽  
Author(s):  
Sota Yonemura ◽  
Takashi Nakamura ◽  
Tatsuya Nabeshima
Keyword(s):  
Cyclodextrin Derivative

pH Dependent In−Out Isomerism of an Amino-β-cyclodextrin Derivative

2006 ◽  
Vol 110 (27) ◽  
pp. 13399-13404 ◽  
Author(s):  
Mercedes Alvarez Alcalde ◽  
Cristina Gancedo ◽  
Aida Jover ◽  
Jorge Carrazana ◽  
Victor H. Soto ◽  
...  
Keyword(s):  
Cyclodextrin Derivative ◽  
Ph Dependent

scholarly journals A new strategy for the sensitive electrochemical determination of nitrophenol isomers using β-cyclodextrin derivative-functionalized silicon carbide

RSC Advances ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. 775-784 ◽  
Author(s):  
Shilian Wu ◽  
Shuangmei Fan ◽  
Shuang Tan ◽  
Jiaqiang Wang ◽  
Can-Peng Li
Keyword(s):  
Silicon Carbide ◽  
Electrochemical Determination ◽  
Cyclodextrin Derivative ◽  
New Strategy

An illustration of simultaneous electrochemical determination of nitrophenol isomers using β-cyclodextrin derivative-functionalized silicon carbide.

scholarly journals Highly efficient cyclosarin degradation mediated by a β-cyclodextrin derivative containing an oxime-derived substituent

2011 ◽  
Vol 7 ◽  
pp. 1543-1554 ◽  
Author(s):  
Michael Zengerle ◽  
Florian Brandhuber ◽  
Christian Schneider ◽  
Franz Worek ◽  
Georg Reiter ◽  
...  
Keyword(s):  
Noncovalent Interactions ◽  
Inhibitory Effect ◽  
Acetylcholinesterase Inhibition ◽  
Cyclodextrin Derivatives ◽  
Physiological Conditions ◽  
Cyclodextrin Derivative ◽  
Cyclodextrin Cavity ◽  
Electronic Parameters ◽  
Narrow Opening

The potential of appropriately substituted cyclodextrins to act as scavengers for neurotoxic organophosphonates under physiological conditions was evaluated. To this end, a series of derivatives containing substituents with an aldoxime or a ketoxime moiety along the narrow opening of the β-cyclodextrin cavity was synthesized, and the ability of these compounds to reduce the inhibitory effect of the neurotoxic organophosphonate cyclosarin on its key target, acetylcholinesterase, was assessed in vitro. All compounds exhibited a larger effect than native β-cyclodextrin, and characteristic differences were noted. These differences in activity were correlated with the structural and electronic parameters of the substituents. In addition, the relatively strong effect of the cyclodextrin derivatives on cyclosarin degradation and, in particular, the observed enantioselectivity are good indications that noncovalent interactions between the cyclodextrin ring and the substrate, presumably involving the inclusion of the cyclohexyl moiety of cyclosarin into the cyclodextrin cavity, contribute to the mode of action. Among the nine compounds investigated, one exhibited remarkable activity, completely preventing acetylcholinesterase inhibition by the (−)-enantiomer of cyclosarin within seconds under the conditions of the assay. Thus, these investigations demonstrate that decoration of cyclodextrins with appropriate substituents represents a promising approach for the development of scavengers able to detoxify highly toxic nerve agents.

Characterization of Interactions in Aqueous Solutions of Hydroxyethylcellulose and Its Hydrophobically Modified Analogue in the Presence of a Cyclodextrin Derivative

2006 ◽  
Vol 110 (13) ◽  
pp. 6601-6608 ◽  
Author(s):  
Neda Beheshti ◽  
Huaitian Bu ◽  
Kaizheng Zhu ◽  
Anna-Lena Kjøniksen ◽  
Kenneth D. Knudsen ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Cyclodextrin Derivative ◽  
Hydrophobically Modified

Elimination kinetics and molecular reaction mechanisms of cyclosarin (GF) by an oxime substituted β-cyclodextrin derivative in vitro

2015 ◽  
Vol 239 (1) ◽  
pp. 41-52 ◽  
Author(s):  
Andreas Kranawetvogl ◽  
Susanne Müller ◽  
Stefan Kubik ◽  
Helma Spruit ◽  
Horst Thiermann ◽  
...  
Keyword(s):  
Reaction Mechanisms ◽  
Elimination Kinetics ◽  
Cyclodextrin Derivative ◽  
Molecular Reaction

scholarly journals Selective Surface Acoustic Wave-Based Organophosphorus Sensor Employing a Host-Guest Self-Assembly Monolayer of β-Cyclodextrin Derivative

Sensors ◽  
2015 ◽  
Vol 15 (8) ◽  
pp. 17916-17925 ◽  
Author(s):  
Yong Pan ◽  
Ning Mu ◽  
Shengyu Shao ◽  
Liu Yang ◽  
Wen Wang ◽  
...  
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Self Assembly ◽  
Cyclodextrin Derivative
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