Preparation of PVA/Polymer Colloid nanocomposite Hydrogel Using PS-PNVA Particles

2019 ◽  
Vol 48 (4) ◽  
pp. 378-381 ◽  
Author(s):  
Naoya Toyoda ◽  
Tetsuya Yamamoto ◽  
Kenji Arakawa ◽  
Aiko Teshima
Author(s):  
Chen Hu ◽  
Malik Haider ◽  
Lukas Hahn ◽  
Mengshi Yang ◽  
Robert Luxenhofer

Hydrogels that can be processed with additive manufacturing techniques and concomitantly possess favorable mechanical properties are interesting for many advanced applications. However, the development of novel ink materials with high...


2021 ◽  
Vol 9 (4) ◽  
pp. 1237-1245
Author(s):  
Yichi Xu ◽  
Heyong Yin ◽  
Jin Chu ◽  
David Eglin ◽  
Tiziano Serra ◽  
...  

An anisotropic magnetically-responsive collagen hydrogel loaded with iron oxide nanoparticles augments aligned cell row formation and tenogenic gene expression of tendon stem/progenitor cells.


JACS Au ◽  
2021 ◽  
Author(s):  
Jason X. Liu ◽  
Navid Bizmark ◽  
Douglas M. Scott ◽  
Richard A. Register ◽  
Mikko P. Haataja ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2363
Author(s):  
Darya A. Kuznetsova ◽  
Dinar R. Gabdrakhmanov ◽  
Denis M. Kuznetsov ◽  
Svetlana S. Lukashenko ◽  
Valery M. Zakharov ◽  
...  

The solution behavior and physicochemical characteristics of polymer–colloid complexes based on cationic imidazolium amphiphile with a dodecyl tail (IA-12) and polyacrylic acid (PAA) or DNA decamer (oligonucleotide) were evaluated using tensiometry, conductometry, dynamic and electrophoretic light scattering and fluorescent spectroscopy and microscopy. It has been established that PAA addition to the surfactant system resulted in a ca. 200-fold decrease in the aggregation threshold of IA-12, with the hydrodynamic diameter of complexes ranging within 100–150 nm. Electrostatic forces are assumed to be the main driving force in the formation of IA-12/PAA complexes. Factors influencing the efficacy of the complexation of IA-12 with oligonucleotide were determined. The nonconventional mode of binding with the involvement of hydrophobic interactions and the intercalation mechanism is probably responsible for the IA-12/oligonucleotide complexation, and a minor contribution of electrostatic forces occurred. The latter was supported by zeta potential measurements and the gel electrophoresis technique, which demonstrated the low degree of charge neutralization of the complexes. Importantly, cellular uptake of the IA-12/oligonucleotide complex was confirmed by fluorescence microscopy and flow cytometry data on the example of M-HeLa cells. While single IA-12 samples exhibit roughly similar cytotoxicity, IA-12–oligonucleotide complexes show a selective effect toward M-HeLa cells (IC50 1.1 µM) compared to Chang liver cells (IC50 23.1 µM).


2021 ◽  
Vol 716 (1) ◽  
pp. 29-40
Author(s):  
Olga Zinchenko ◽  
Valentyna Ezhova ◽  
Olga Slisenko ◽  
Alexander Tolstov

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