scholarly journals Design of Temperature-Responsive Polymer-Grafted Surfaces for Cell Sheet Preparation and Manipulation

2019 ◽  
Vol 92 (4) ◽  
pp. 817-824 ◽  
Author(s):  
Jun Kobayashi ◽  
Teruo Okano
2015 ◽  
Vol 3 (40) ◽  
pp. 7899-7902 ◽  
Author(s):  
E. L. Lee ◽  
H. H. Bendre ◽  
A. Kalmykov ◽  
J. Y. Wong

Because current cell sheet-based blood vessels lack biomimetic structure and require excessively long culture times that may compromise smooth muscle cell phenotype, we modified a cell culture platform with thermoresponsive copolymers to allow intact cell sheet detachment after uniaxial conditioning.


Polymers ◽  
2012 ◽  
Vol 4 (3) ◽  
pp. 1478-1498 ◽  
Author(s):  
Zhonglan Tang ◽  
Yoshikatsu Akiyama ◽  
Teruo Okano

MRS Bulletin ◽  
2005 ◽  
Vol 30 (3) ◽  
pp. 189-193 ◽  
Author(s):  
Joseph Yang ◽  
Masayuki Yamato ◽  
Teruo Okano

AbstractThe possibility of recreating various tissues and organs for the purpose of regenerative medicine has received much interest. However, the field of tissue engineering has been restricted by the limitations of conventional approaches. A method to circumvent the need for traditional scaffold-based technologies is cell-sheet engineering, which uses temperature-responsive culture dishes. These surfaces, which are created by grafting the temperature-responsive polymer poly(N-isopropylacrylamide) onto ordinary culture dishes, enable the non-invasive harvesting of cells as intact sheets by simple temperature reduction. This article reviews current research on the applications of cell-sheet engineering for the reconstruction of various tissues, as well as the intelligent surfaces used by this novel technology.


2007 ◽  
Vol 83A (3) ◽  
pp. 692-695 ◽  
Author(s):  
Donald E. Owens ◽  
Jackson K. Eby ◽  
Yicun Jian ◽  
Nicholas A. Peppas

2019 ◽  
pp. 457-470
Author(s):  
Jun Kobayashi ◽  
Yoshikatsu Akiyama ◽  
Masayuki Yamato ◽  
Teruo Okano

2019 ◽  
Vol 7 (21) ◽  
pp. 1901103 ◽  
Author(s):  
Augustinus J. J. Kragt ◽  
Iris P. M. Gessel ◽  
Albertus P. H. J. Schenning ◽  
Dirk J. Broer

ACS Nano ◽  
2013 ◽  
Vol 7 (10) ◽  
pp. 8561-8572 ◽  
Author(s):  
Thomas R. Wilks ◽  
Jonathan Bath ◽  
Jan Willem de Vries ◽  
Jeffery E. Raymond ◽  
Andreas Herrmann ◽  
...  

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