scholarly journals Three auditory brainstem response (ABR) methods tested and compared in two anuran species

2020 ◽  
pp. jeb.237313
Author(s):  
Tanya B. Lauridsen ◽  
Christian Brandt ◽  
Jakob Christensen-Dalsgaard
Keyword(s):  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Nerve Fibers ◽  
Good Choice ◽  
Low Frequencies ◽  
Hearing Sensitivity ◽  
Frequency Specificity ◽  
Long Duration ◽  
Brainstem Response ◽  
The Difference

Hearing sensitivity has been extensively investigated, often by measuring the auditory brainstem response (ABR). ABR measurements are relatively non-invasive, easy to reproduce, and allow the assessment of sensitivity when psychophysical data are difficult to obtain. However, the experimental methods differ greatly in respect to stimulation, which may result in different audiograms.We used three different methods in the same individual frogs: Stimulating with brief tone bursts (tABR), long-duration tones (ltABR), and masked ABR (mABR) where transients are masked by a long-duration sinusoid, and the sensitivity is assessed by the difference between unmasked and masked ABR.We measured sensitivity in a range from 100 to 3500 Hz, and the resulting audiograms show two sensitivity peaks at 400-600 Hz and 1500-1600 Hz (both sensitive down to 30 dB re. 20 µPa). We found similar results below 1000 Hz, but when stimulating with long-duration tones, the sensitivity decreased more rapidly above this frequency. We showed that the frequency specificity of tone bursts becomes poorly defined with shorter duration at low frequencies. Comparisons between subjectively (visual inspection by researchers) and objectively (thresholds defined by SNR) defined audiograms showed very little variation. In conclusion the mABR method gave the most sensitive audiograms. The tABR method showed a similar audiogram, when using relatively long-duration tone bursts (25 ms). The ltABR method is not a good choice for studying hearing thresholds above 1000 Hz, because of the bias introduced by spike rate saturation in the nerve fibers and their inability to phase lock.

Analysis of Click and Swept-Tone Auditory Brainstem Response Results for Moderate and Severe Sensorineural Hearing Loss

2020 ◽  
Vol 25 (6) ◽  
pp. 336-344
Author(s):  
Jingqian Tan ◽  
Jia Luo ◽  
Xin Wang ◽  
Yanbing Jiang ◽  
Xiangli Zeng ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Auditory Brainstem Response ◽  
Basilar Membrane ◽  
Auditory Brainstem ◽  
Sensorineural Hearing ◽  
Control Group ◽  
Hearing Sensitivity ◽  
Brainstem Response ◽  
Frequency Components

<b><i>Introduction:</i></b> Auditory brainstem response (ABR) is one of the commonly used methods in clinical settings to evaluate the hearing sensitivity and auditory function. The current ABR measurement usually adopts click sound as the stimuli. However, there may be partial ABR amplitude attenuation due to the delay characteristics of the cochlear traveling wave along the basilar membrane. To solve that problem, a swept-tone method was proposed, in which the show-up time of different frequency components was adjusted to compensate the delay characteristics of the cochlear basilar membrane; therefore, different ABR subcomponents of different frequencies were synchronized. <b><i>Methods:</i></b> The normal hearing group, moderate sensorineural hearing loss group, and severe sensorineural hearing loss group underwent click ABR and swept-tone ABR with different stimulus intensities. The latencies and amplitudes of waves I, III, and V in 2 detections were recorded. <b><i>Results:</i></b> It was found that the latency of each of the recorded I, III, and V waves detected by swept-tone ABR was shorter than that by click ABR in both the control group and experimental groups. In addition, the amplitude of each of the recorded I, III, and V waves, except V waves under 60 dB nHL in the moderate sensorineural hearing loss group, detected by swept-tone ABR was larger than that by click ABR. The results also showed that the swept-tone ABR could measure the visible V waves at lower stimulus levels in the severe sensorineural hearing loss group. <b><i>Conclusion:</i></b> Swept-tone improves the ABR waveforms and helps to obtain more accurate threshold to some extent. Therefore, the proposed swept-tone ABR may provide a new solution for better morphology of ABR waveform, which can help to make more accurate diagnosis about the hearing functionality in the clinic.

scholarly journals The Parallel Auditory Brainstem Response

2019 ◽  
Vol 23 ◽  
pp. 233121651987139 ◽  
Author(s):  
Melissa J. Polonenko ◽  
Ross K. Maddox
Keyword(s):  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Test Duration ◽  
Recording Time ◽  
Low Frequencies ◽  
Periodic Sequences ◽  
Hearing Thresholds ◽  
Long Time ◽  
Brainstem Response ◽  
Indispensable Tool

The frequency-specific tone-evoked auditory brainstem response (ABR) is an indispensable tool in both the audiology clinic and research laboratory. Most frequently, the toneburst ABR is used to estimate hearing thresholds in infants, toddlers, and other patients for whom behavioral testing is not feasible. Therefore, results of the ABR exam form the basis for decisions regarding interventions and hearing habilitation with implications extending far into the child’s future. Currently, responses are elicited by periodic sequences of toneburst stimuli presented serially to one ear at a time, which take a long time to measure multiple frequencies and intensities, and provide incomplete information if the infant wakes up early. Here, we describe a new method, the parallel ABR (pABR), which uses randomly timed toneburst stimuli to simultaneously acquire ABR waveforms to five frequencies in both ears. Here, we describe the pABR and quantify its effectiveness in addressing the greatest drawback of current methods: test duration. We show that in adults with normal hearing the pABR yields high-quality waveforms over a range of intensities, with similar morphology to the standard ABR in a fraction of the recording time. Furthermore, longer latencies and smaller amplitudes for low frequencies at a high intensity evoked by the pABR versus serial ABR suggest that responses may have better place specificity due to the masking provided by the other simultaneous toneburst sequences. Thus, the pABR has substantial potential for facilitating faster accumulation of more diagnostic information that is important for timely identification and treatment of hearing loss.

scholarly journals The Auditory Brainstem Response: Latencies Obtained in Children While under General Anesthesia

2012 ◽  
Vol 23 (01) ◽  
pp. 057-063 ◽  
Author(s):  
Linda W. Norrix ◽  
Stacey Trepanier ◽  
Matthew Atlas ◽  
Darlyne Kim
Keyword(s):  
General Anesthesia ◽  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Control Group ◽  
Neural Function ◽  
General Anesthetic ◽  
Response Latencies ◽  
Hearing Sensitivity ◽  
Brainstem Response ◽  
Group Delays

Background: The auditory brainstem response (ABR) test is frequently employed to estimate hearing sensitivity and assess the integrity of the ascending auditory system. In persons who cannot participate in conventional tests of hearing, a short-acting general anesthetic is used, recordings are obtained, and the results are compared with normative data. However, several factors (e.g., anesthesia, temperature changes) can contribute to delayed absolute and interpeak latencies, making it difficult to evaluate the integrity of the person's auditory brainstem function. Purpose: In this study, we investigated the latencies of ABR responses in children who received general anesthesia. Research Design: Between subject. Study Sample: Twelve children between the ages of 29 and 52 mo, most of whom exhibited a developmental delay but normal peripheral auditory function, comprised the anesthesia group. Twelve participants between the ages of 13 and 26 yr with normal hearing thresholds comprised the control group. Data Collection and Analysis: ABRs from a single ear from children, recorded under general anesthesia, were retrospectively analyzed and compared to those obtained from a control group with no anesthesia. ABRs were generated using 80 dB nHL rarefaction click stimuli. T-tests, corrected for alpha slippage, were employed to examine latency differences between groups. Results: There were significant delays in latencies for children evaluated under general anesthesia compared to the control group. Delays were observed for wave V and the interpeak intervals I–III, III–V, and I–V. Conclusions: Our data suggest that caution is needed in interpreting neural function from ABR data recorded while a child is under general anesthesia.

scholarly journals The Vestibular-Auditory Interaction for Auditory Brainstem Response to Low Frequencies

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Seyede Faranak Emami ◽  
Nasrin Gohari
Keyword(s):  
Auditory Brainstem Response ◽  
Tone Burst ◽  
Auditory Brainstem ◽  
Case Control ◽  
Vestibular Evoked Myogenic Potentials ◽  
Medical Sciences ◽  
Low Frequencies ◽  
Control Research ◽  
Brainstem Response ◽  
Vestibular Assessment

Since saccular projection is sound sensitive, the objective is to investigate the possibility that the saccular projections may contribute to auditory brainstem response to 500 HZ tone burst (ABR500 HZ). During the case-control research, twenty healthy controls compared to forty selected case groups as having chronic and resistant BPPV were evaluated in the audiology department of Hamadan University of Medical Sciences (Hamadan, Iran). Assessment is comprised of audiologic examinations, cervical vestibular evoked myogenic potentials (cVEMPs), and ABR500 HZ. We found that forty affected ears of BPPV patients with decreased vestibular excitability as detected by abnormal cVEMPs had abnormal results in ABR500 HZ, whereas unaffected ears presented normal findings. Multiple comparisons of mean p13, n23 latencies, and peak-to-peak amplitudes between three groups (affected, unaffected, and healthy ears) were significant. In conclusion, the saccular nerves can be projective to auditory bundles and interact with auditory brainstem response to low frequencies. Combine the cVEMPs and ABR500 HZ in battery approach tests of vestibular assessment and produce valuable data for judgment on the site of lesion. Regarding vestibular cooperation for making of wave V, it is reasonable that the term of ABR500 HZ is not adequate and the new term or vestibular-auditory brainstem response to 500 HZ tone burst is more suitable.

Auditory Brainstem and Middle Latency Evoked Response Sensitivity near Threshold

1981 ◽  
Vol 90 (3) ◽  
pp. 236-240 ◽  
Author(s):  
Frank E. Musiek ◽  
Nathan A. Geurkink
Keyword(s):  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Evoked Response ◽  
Response Sensitivity ◽  
Hearing Sensitivity ◽  
Brainstem Response ◽  
Middle Latency ◽  
Near Threshold

Auditory brainstem response (ABR) and middle latency evoked response (MLER) testing have been used successfully for assessing hearing sensitivity electrophysiologically. Though both procedures have their proponents, ABR seems to be the more popular of the two. However, this study shows that overall, MLER waves occur with greater frequency at low sensation levels than ABR waves. Specifically, MLER wave Pa was the most sensitive wave, followed by ABR wave V, MLER wave Pb, ABR wave III, MLER wave Pc, and ABR wave I. Latencies were more consistent and predictable for ABR than MLER. However, as expected, amplitudes for MLER waves were greater than those for ABR. Given these results, those involved in measuring hearing sensitivity electrophysiologically are encouraged to consider the potential of the MLER measure and not limit their scope of assessment to ABR.

The Impact of Clinical History on the Threshold Estimation of Auditory Brainstem Response Results for Infants

2017 ◽  
Vol 60 (3) ◽  
pp. 725-731 ◽  
Author(s):  
Maha Zaitoun ◽  
Steven Cumming ◽  
Alison Purcell ◽  
Katie O'Brien
Keyword(s):  
Auditory Brainstem Response ◽  
Hearing Threshold ◽  
Clinical Information ◽  
Clinical History ◽  
Auditory Brainstem ◽  
True Negative ◽  
History Information ◽  
Brainstem Response ◽  
The Difference ◽  
The Impact

Purpose This study assesses the impact of patient clinical history on audiologists' performance when interpreting auditory brainstem response (ABR) results. Method Fourteen audiologists' accuracy in estimating hearing threshold for 16 infants through interpretation of ABR traces was compared on 2 occasions at least 5 months apart. On the 1st occasion, ABR traces were presented to the audiologists with no clinical information except for the age of the child. On the 2nd occasion, audiologists were given a full clinical history for the ABR cases. Results The addition of clinical history information had no statistically significant impact on sensitivity, specificity, or accuracy of diagnosis. Although the mean numbers of true-negative and true-positive diagnoses were higher when audiologists were given clinical information, the difference was again not statistically significant. Conclusion This study suggests that if there are circumstances in which case material is incomplete or unavailable, audiologists have no cause for concern regarding the accuracy of their interpretation of ABR traces. In a clinical manner, this may help audiologists with large caseloads or audiologists who need to provide a diagnosis of hearing loss in a short time by allowing them to focus on conducting ABR without the need for case history information.

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