scholarly journals Repeated stimulation of the pituitary–adrenal axis alters offspring phenotype of a wild passerine

2019 ◽  
Vol 222 (10) ◽  
pp. jeb200659
Author(s):  
Vallo Tilgar
Keyword(s):  
Repeated Stimulation ◽  
Adrenal Axis ◽  
Pituitary Adrenal Axis ◽  
Stimulation Of

Single-dose metyrapone test at 06.00 h: an accurate method for assessment of pituitary-adrenal reserve

1986 ◽  
Vol 112 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Gabriel Dickstein ◽  
Michal Lahav ◽  
Zila Shen Orr
Keyword(s):  
Single Dose ◽  
Accurate Method ◽  
Accurate Assessment ◽  
Adrenal Failure ◽  
Normal Range ◽  
Normal Response ◽  
Adrenal Axis ◽  
Subsequent Measurement ◽  
Pituitary Adrenal Axis ◽  
Stimulation Of

Abstract. One dose of metyrapone (1.5 g) administered at 06.00 h, with subsequent measurement of 11-deoxycortisol and 17-hydroxycorticosteroid (17-OHCS) levels in plasma at 12.00 and 14.00 h, allowed accurate assessment of the pituitary-adrenal reserve. Normal response was defined as achieving a serum 17-OHCS level of more than 10.0 μg/100 ml and a 11-deoxycortisol level of more than 6.0 μg/100 ml at either 12.00 or 14.00 h. These criteria are based on a group of 18 persons with normal pituitary-adrenal axis, and 86 additional cases responded in this normal range. In this group of 104 subjects, 11-deoxycortisol levels rose to 9.2 ± 3.5 μg/100 ml at noon and 17-OHCS levels to 15.4 ± 4.7 μg/100 ml at 14.00 h. Post-metyrapone 17-OHCS levels were significantly higher than normal cortisol levels at these times (P < 0.001) and than those observed at 08.00 h on the day of the test, demonstrating stimulation of adrenal corticoid production in addition to blockade of cortisol production by metyrapone. Thirty-one patients found to suffer from secondary adrenal failure showed impaired response. All these patients had limited pituitary-adrenal reserve, either proven by other pituitary-adrenal tests or implicated by severe pituitary disease.

Naloxone does not antagonize PCP-induced stimulation of the pituitary-adrenal axis in the rat

Life Sciences ◽  
1989 ◽  
Vol 44 (2) ◽  
pp. 143-147 ◽  
Author(s):  
Robert N. Pechnick ◽  
Robert George ◽  
Russell E. Poland
Keyword(s):  
Adrenal Axis ◽  
Pituitary Adrenal Axis ◽  
Stimulation Of

Stimulation of the Hypothalamic-Pituitary-Adrenal Axis with the Opioid Antagonist Nalmefene

Pituitary ◽  
2005 ◽  
Vol 8 (2) ◽  
pp. 115-122 ◽  
Author(s):  
Eliza B Geer ◽  
Rita E Landman ◽  
Sharon L Wardlaw ◽  
Irene M Conwell ◽  
Pamela U. Freda
Keyword(s):  
Hypothalamic Pituitary Adrenal Axis ◽  
Opioid Antagonist ◽  
Hypothalamic Pituitary Adrenal ◽  
Adrenal Axis ◽  
Pituitary Adrenal Axis ◽  
Stimulation Of

Acute stimulation of the hypothalamic-pituitary-adrenal axis by IL-1ß, TNFα and IL-6: A dose response study

1996 ◽  
Vol 19 (3) ◽  
pp. 175-182 ◽  
Author(s):  
M. J. M. van der Meer ◽  
C. G. J. Sweep ◽  
C. E. M. Rijnkels ◽  
G. J. Pesman ◽  
F. J. H. Tilders ◽  
...  
Keyword(s):  
Dose Response ◽  
Hypothalamic Pituitary Adrenal Axis ◽  
Hypothalamic Pituitary Adrenal ◽  
Adrenal Axis ◽  
Dose Response Study ◽  
Pituitary Adrenal Axis ◽  
Stimulation Of
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