scholarly journals A second visual rhodopsin gene,rh1-2, is expressed in zebrafish photoreceptors and found in other ray-finned fishes

2016 ◽  
Vol 220 (2) ◽  
pp. 294-303 ◽  
Author(s):  
James M. Morrow ◽  
Savo Lazic ◽  
Monica Dixon Fox ◽  
Claire Kuo ◽  
Ryan K. Schott ◽  
...  
Keyword(s):  
Rhodopsin Gene ◽  
Visual Rhodopsin

Further Screening of the Rhodopsin Gene in Patients with Autosomal Dominant Retinitis Pigmentosa

Genomics ◽  
1994 ◽  
Vol 21 (2) ◽  
pp. 461-463 ◽  
Author(s):  
Rajani Vaithinathan ◽  
Eliot L. Berson ◽  
Thaddeus P. Dryja
Keyword(s):  
Retinitis Pigmentosa ◽  
Autosomal Dominant ◽  
Autosomal Dominant Retinitis Pigmentosa ◽  
Rhodopsin Gene

Functional expression in vitro of bovine visual rhodopsin

1990 ◽  
Vol 3 (5) ◽  
pp. 453-458 ◽  
Author(s):  
S.A. Zozulya ◽  
V.V. Gurevich ◽  
T.A. Zvyaga ◽  
E.P. Shirokova ◽  
I.L. Dumler ◽  
...  
Keyword(s):  
Functional Expression ◽  
Visual Rhodopsin

scholarly journals Genetic Analysis of the Rhodopsin Gene Identifies a Mosaic Dominant Retinitis Pigmentosa Mutation in a Healthy Individual

2016 ◽  
Vol 57 (3) ◽  
pp. 940 ◽  
Author(s):  
Avigail Beryozkin ◽  
Gal Levy ◽  
Anat Blumenfeld ◽  
Segev Meyer ◽  
Prasanthi Namburi ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
Retinitis Pigmentosa ◽  
Healthy Individual ◽  
Rhodopsin Gene

scholarly journals The rhodopsin-retinochrome system for retinal re-isomerization predates the origin of cephalopod eyes

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Oliver Vöcking ◽  
Lucas Leclère ◽  
Harald Hausen
Keyword(s):  
In Situ Hybridization ◽  
Photoreceptor Cells ◽  
Visual Cycle ◽  
Phylogenetic Distribution ◽  
Enzymatic Process ◽  
Antibody Staining ◽  
The Individual ◽  
Functional Components ◽  
Visual Rhodopsin

Abstract Background The process of photoreception in most animals depends on the light induced isomerization of the chromophore retinal, bound to rhodopsin. To re-use retinal, the all-trans-retinal form needs to be re-isomerized to 11-cis-retinal, which can be achieved in different ways. In vertebrates, this mostly includes a stepwise enzymatic process called the visual cycle. The best studied re-isomerization system in protostomes is the rhodopsin-retinochrome system of cephalopods, which consists of rhodopsin, the photoisomerase retinochrome and the protein RALBP functioning as shuttle for retinal. In this study we investigate the expression of the rhodopsin-retinochrome system and functional components of the vertebrate visual cycle in a polyplacophoran mollusk, Leptochiton asellus, and examine the phylogenetic distribution of the individual components in other protostome animals. Results Tree-based orthology assignments revealed that orthologs of the cephalopod retinochrome and RALBP are present in mollusks outside of cephalopods. By mining our dataset for vertebrate visual cycle components, we also found orthologs of the retinoid binding protein RLBP1, in polyplacophoran mollusks, cephalopods and a phoronid. In situ hybridization and antibody staining revealed that L. asellus retinochrome is co-expressed in the larval chiton photoreceptor cells (PRCs) with the visual rhodopsin, RALBP and RLBP1. In addition, multiple retinal dehydrogenases are expressed in the PRCs, which might also contribute to the rhodopsin-retinochrome system. Conclusions We conclude that the rhodopsin-retinochrome system is a common feature of mollusk PRCs and predates the origin of cephalopod eyes. Our results show that this system has to be extended by adding further components, which surprisingly, are shared with vertebrates.

scholarly journals Rhodopsin Gene Expression Determines Rod Outer Segment Size and Rod Cell Resistance to a Dominant-Negative Neurodegeneration Mutant

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49889 ◽  
Author(s):  
Brandee A. Price ◽  
Ivette M. Sandoval ◽  
Fung Chan ◽  
Ralph Nichols ◽  
Ramon Roman-Sanchez ◽  
...  
Keyword(s):  
Gene Expression ◽  
Outer Segment ◽  
Dominant Negative ◽  
Cell Resistance ◽  
Rhodopsin Gene ◽  
Rod Outer Segment ◽  
Segment Size ◽  
Rod Cell

Modeling the allosteric effect in visual rhodopsin due to phosphorylation

2018 ◽  
Vol 18 (2) ◽  
pp. 94-98
Author(s):  
N. Vasilieva-Vashakmadze ◽  
G. Lekishvili ◽  
P. Toidze ◽  
R. Gakhokidze
Keyword(s):  
Allosteric Effect ◽  
Visual Rhodopsin

scholarly journals To see in different seas: spatial variation in the rhodopsin gene of the sand goby (Pomatoschistus minutus)

2009 ◽  
Vol 18 (20) ◽  
pp. 4227-4239 ◽  
Author(s):  
MAARTEN H. D. LARMUSEAU ◽  
JOOST A. M. RAEYMAEKERS ◽  
KEVIN G. RUDDICK ◽  
JEROEN K. J. VAN HOUDT ◽  
FILIP A. M. VOLCKAERT
Keyword(s):  
Spatial Variation ◽  
Sand Goby ◽  
Rhodopsin Gene ◽  
Pomatoschistus Minutus
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