Cellular aspects of regeneration hormone influence in Nereis diversicolor

Development ◽  
1974 ◽  
Vol 32 (1) ◽  
pp. 111-131
Author(s):  
P. J. W. Olive

The histology of caudal regeneration in Nereis diversicolor is described with special reference to the role of the cerebral ‘regeneration’ hormone. Wound healing is complete after 8 days; the regenerated stump of tissue then consists of the pygidium, associated anal cirri and a prepygidial region between the pygidium and the posterior margin of the last intact segment. The term segment blastema is used to refer to the cells from which all segmental structures are derived. The segment blastema is situated in the ventral posterior margin of the prepygidial region, and consists of transverse bands of cells with large nuclei (12 µm diameter) and prominent nucleoli. Segment anlagen are formed immediately in front of the segment blastema; the development of the anlagen is described, and six stages of development are defined. The extent of caudal regeneration in different animals is best compared with reference to the total number and stage of development reached by the segment anlagen. Duringnormal regeneration at 18 °C, segment anlagen are first formed after 8 days, and they continue to be formed at the same rate until at least the 21st day after caudal ablation. The oldest segments reach stage 6 after about 15 days of regeneration. Wound healing, pygidium formation, and cirrus development and establishment of the segment blastema all occur in decerebrate animals following the loss of caudal segments, but segment anlagen formation is almost completely inhibited. Implantation of ganglia taken from intact donor animals into the coelom of decerebrate animals which have lost caudal segments initiates segment anlagen formation. The segment blastema of decerebrate animals remains competent to respond in this way for at least 15 days. The regeneration hormone produced by the cerebral ganglion is essential for continued segment anlagen production throughout the 2nd and 3rd weeks of regeneration at 18 °C. Delayed decerebration leads to an arrest of anlagen production, and anlagen younger than stage 3 fail to develop further. Older anlagen (stages 4 and 5) are independent of the regeneration hormone and can continue to differentiate in its absence.

1975 ◽  
Vol 8 (5) ◽  
pp. 268-270 ◽  
Author(s):  
W P Feistritzer

In this short article the author indicates the present stages of development of variety evaluation, testing, certification, production and marketing of quality seed—of cereals, industrial crops, pasture plants and vegetables—in major geographical regions of the world and draws attention to some of the underlying problems which must be faced in the future if further progress is to be made.


Cureus ◽  
2018 ◽  
Author(s):  
Chellappa Vijayakumar ◽  
Ravi Prabhu ◽  
M Senthil Velan ◽  
Vallinayagam Muthu Krishnan ◽  
Raja Kalaiarasi ◽  
...  

WCET Journal ◽  
2019 ◽  
Vol 39 (2) ◽  
pp. 9-18
Author(s):  
Wai Sze Ho ◽  
Wai Kuen Lee ◽  
Ka Kay Chan ◽  
Choi Ching Fong

Objectives The aim of this study was to retrospectively review the effectiveness of negative pressure wound therapy (NPWT) in sternal wound healing with the use of the validated Bates-Jensen Wound Assessment Tool (BWAT), and explore the role of NPWT over sternal wounds and future treatment pathways. Methods Data was gathered from patients' medical records and the institution's database clinical management system. Seventeen subjects, who had undergone cardiothoracic surgeries and subsequently consulted the wound care team in one year were reviewed. Fourteen of them were included in the analysis. Healing improvement of each sternal wound under continuous NPWT and continuous conventional dressings was studied. In total, 23 continuous NPWT and 13 conventional dressing episodes were analysed with the BWAT. Results Among conventional dressing episodes, sternal wound improvement was 2.5–3% over 10 days to 3.5 weeks, whereas 4–5% sternal healing was achieved in 5 days to 2 weeks with sternal wire presence. Better healing at 11% in 1 week by conventional dressing was attained after sternal wire removal. In NPWT episodes, 8–29%, 13–24%, and 15–46% of healing was observed in 2 weeks, 3.5 to 5 weeks and 6 to 7 weeks, respectively. Only 39% wound healing was acquired at the 13th week of NPWT in one subject. With sternal wire present, 6%–29% wound healing progress was achieved by NPWT in 1–4 weeks, and 16–23% wound improvement in 2 to 4.5 weeks by NWPT after further surgical debridement. After sternal wire removal, 6–34% sternal wound healing occurred by continuous NPWT for 1–2 weeks, and maximum healing at 46% after 2.5 weeks of NPWT were observed. Conclusions Better wound healing was achieved in the NPWT group in comparison to conventional dressings alone. However, suboptimal sternal wound healing by NPWT alone was observed. Removal of sternal wire may improve the effectiveness of NPWT. Successful tertiary closure after NPWT among subjects supports the important bridging role of NPWT in sternal wound healing. Factors causing stagnant sternal wound healing by NPWT alone are discussed.


Leczenie Ran ◽  
2015 ◽  
Vol 11 (4) ◽  
pp. 171-178
Author(s):  
Beata Mrozikiewicz-Rakowska ◽  
Joanna Kania ◽  
Ewelina Bucior ◽  
Adriana Nowak ◽  
Tomasz Grzela ◽  
...  

Leczenie Ran ◽  
2013 ◽  
Vol 10 (2) ◽  
pp. 41-45
Author(s):  
Ewa Rojczyk-Gołębiewska ◽  
Marek Kucharzewski ◽  
Katarzyna Wilemska-Kucharzewska ◽  
Artur Pałasz
Keyword(s):  

2020 ◽  
Vol 2 (3) ◽  
pp. 01-03
Author(s):  
Ravi Chittoria

Pressure ulcer or pressure sore is one of the complications seen in bedridden patients. Management of these ulcers is often challenging. But there is no well-established method that accelerates the wound healing rate. Various adjunctive methods are used for wound bed preparation before definitive reconstruction plan is made. Here we describe our experience in the role of insulin therapy as an adjunct in the management of pressure sores.


Author(s):  
A. Kulikov

Presented material reveals main links in the pathogenesis of hemostatic disorder. In particular, attention is paid to the role of the lungs, liver and other organs in the development of this process. Role of vascular wall and blood cells in regulation of the physical state of blood is described in detail. The most frequent factors leading to hypercoagulation are indicated. Difference between hypercoagulation and thrombophilia is shown. The latter is found in clinical practice quite often, but at the same time, it is poorly diagnosed. Such a terrible complication of hemostatic disorder as disseminated intravascular coagulation is described. Its classification, stages of development, clinical manifestations are offered to the readers.


2020 ◽  
Vol 2 (8) ◽  
pp. 83-87
Author(s):  
B. Kh. ALIYEV ◽  

In the Russian Federation, the problem of budget planning becomes especially relevant when the pace of economic development slows down. The article examines the features of the formation of regional budgets, using the example of the budget of the Republic of Dagestan. The analysis of incomes to the budget is carried out. The role of regional taxes in the formation of budget revenues of the Republic of Dagestan is revealed. According to the results of the study, it can be concluded that the budgetary policy of the regions at the present stage of development of the Russian economies does not contribute to a further increase in the rates of economic growth. The article offers recommendations for improving the regional budgetary policy of the Russian Federation and increasing the responsibility of regional authorities.


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