scholarly journals Modeling human lung development and disease using pluripotent stem cells

Development ◽  
2014 ◽  
Vol 142 (1) ◽  
pp. 13-16 ◽  
Author(s):  
H.-W. Snoeck
Keyword(s):  
Stem Cells ◽  
Pluripotent Stem Cells ◽  
Lung Development ◽  
Human Lung

scholarly journals A three-dimensional model of human lung development and disease from pluripotent stem cells

2017 ◽  
Vol 19 (5) ◽  
pp. 542-549 ◽  
Author(s):  
Ya-Wen Chen ◽  
Sarah Xuelian Huang ◽  
Ana Luisa Rodrigues Toste de Carvalho ◽  
Siu-Hong Ho ◽  
Mohammad Naimul Islam ◽  
...  
Keyword(s):  
Stem Cells ◽  
Pluripotent Stem Cells ◽  
Lung Development ◽  
Human Lung ◽  
Three Dimensional ◽  
Dimensional Model ◽  
Three Dimensional Model

scholarly journals Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells

2017 ◽  
Vol 127 (6) ◽  
pp. 2277-2294 ◽  
Author(s):  
Finn Hawkins ◽  
Philipp Kramer ◽  
Anjali Jacob ◽  
Ian Driver ◽  
Dylan C. Thomas ◽  
...  
Keyword(s):  
Stem Cells ◽  
Pluripotent Stem Cells ◽  
Human Lung ◽  
Lung Progenitors ◽  
Prospective Isolation

scholarly journals Use of three-dimensional organoids and lung-on-a-chip methods to study lung development, regeneration and disease

2018 ◽  
Vol 52 (5) ◽  
pp. 1800876 ◽  
Author(s):  
Konstantinos Gkatzis ◽  
Sara Taghizadeh ◽  
Dongeun Huh ◽  
Didier Y.R. Stainier ◽  
Saverio Bellusci
Keyword(s):  
Pluripotent Stem Cells ◽  
Lung Development ◽  
Animal Studies ◽  
Human Lung ◽  
Unmet Need ◽  
Three Dimensional ◽  
Lung Cells ◽  
Lung Physiology ◽  
And Function

Differences in lung anatomy between mice and humans, as well as frequently disappointing results when using animal models for drug discovery, emphasise the unmet need for in vitro models that can complement animal studies and improve our understanding of human lung physiology, regeneration and disease. Recent papers have highlighted the use of three-dimensional organoids and organs-on-a-chip to mimic tissue morphogenesis and function in vitro. Here, we focus on the respiratory system and provide an overview of these in vitro models, which can be derived from primary lung cells and pluripotent stem cells, as well as healthy or diseased lungs. We emphasise their potential application in studies of respiratory development, regeneration and disease modelling.

Directed differentiation of mouse-induced pluripotent stem cells generates dopaminergic nerve

2010 ◽  
Vol 34 (8) ◽  
pp. S36-S36
Author(s):  
Ping Duan ◽  
Xuelin Ren ◽  
Wenhai Yan ◽  
Xuefei Han ◽  
Xu Yan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Directed Differentiation ◽  
Induced Pluripotent

Human myocardial extracellular matrix directs the differentiation of pluripotent stem cells toward a cardiomyocyte phenotype

2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
B. Oberwallner ◽  
A. Brodarac ◽  
P. Anic ◽  
T. Saric ◽  
K. Bieback ◽  
...  
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Pluripotent Stem Cells

Generation of Clara cells from murine pluripotent stem cells – a new tool to explore airway epithelial regeneration

Pneumologie ◽  
2014 ◽  
Vol 68 (06) ◽  
Author(s):  
K Katsirntaki ◽  
C Mauritz ◽  
S Schmeckebier ◽  
M Sgodda ◽  
V Puppe ◽  
...  
Keyword(s):  
Stem Cells ◽  
Pluripotent Stem Cells ◽  
Airway Epithelial ◽  
Clara Cells ◽  
Epithelial Regeneration
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