ERRATUM

Development ◽  
1988 ◽  
Vol 104 (4) ◽  
pp. 525-s-525

The authors made an error in the institution address for the article: The expression of rat homeobox-containing genes is developmentally regulated and tissue specific in Development103, 601–610 (1988) The correct institution address should read: MIRIAM FALZON1 and SU YUN CHUNG Laboratory of Experimental Carcinogenesis, National Cancer Institute, Bethesda, MD 20892 and Department of Biochemistry, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA Note: Present address: Laboratory of Biochemistry. National Cancer Institute, Bethesda. MD 20892, USA

2000 ◽  
Vol 275 (9) ◽  
pp. 6368-6374 ◽  
Author(s):  
Hitoshi Shirakawa ◽  
David Landsman ◽  
Yuri V. Postnikov ◽  
Michael Bustin

1989 ◽  
Vol 261 (1) ◽  
pp. 227-232 ◽  
Author(s):  
R P Paulovic ◽  
R A Anwar

The data presented clearly suggest that relative amounts of mRNAs for elastins a, b and c are developmentally regulated in foetal-calf nuchal ligament and aorta and that this regulation is tissue-specific. In nuchal ligament, at earlier stages of foetal development, the relative amounts of mRNAs for elastins a and b are very low. After the foetal age of about 6 months the relative amount of mRNA for elastin b begins to increase. This is followed by an increase in the relative amount of mRNA for elastin a. In aorta, with increasing foetal age, the relative amounts of mRNAs for elastins b and c increase and decrease alternately. The relative amounts of mRNA for elastin a remain low, with only marginal increases with foetal age. A possible self-aggregation role of elastin a in elastogenesis is proposed.


1986 ◽  
Vol 6 (7) ◽  
pp. 2624-2631 ◽  
Author(s):  
M Shani

A chimeric plasmid containing about 2/3 of the rat skeletal muscle actin gene plus 730 base pairs of its 5' flanking sequences fused to the 3' end of a human embryonic globin gene (D. Melloul, B. Aloni, J. Calvo, D. Yaffe, and U. Nudel, EMBO J. 3:983-990, 1984) was inserted into mice by microinjection into fertilized eggs. Eleven transgenic mice carrying the chimeric gene with or without plasmid pBR322 DNA sequences were identified. The majority of these mice transmitted the injected DNA to about 50% of their progeny. However, in transgenic mouse CV1, transmission to progeny was associated with amplification or deletion of the injected DNA sequences, while in transgenic mouse CV4 transmission was distorted, probably as a result of insertional mutagenesis. Tissue-specific expression was dependent on the removal of the vector DNA sequences from the chimeric gene sequences prior to microinjection. None of the transgenic mice carrying the chimeric gene together with plasmid pBR322 sequences expressed the introduced gene in striated muscles. In contrast, the six transgenic mice carrying the chimeric gene sequences alone expressed the inserted gene specifically in skeletal and cardiac muscles. Moreover, expression of the chimeric gene was not only tissue specific, but also developmentally regulated. Similar to the endogenous skeletal muscle actin gene, the chimeric gene was expressed at a relatively high level in cardiac muscle of neonatal mice and at a significantly lower level in adult cardiac muscle. These results indicate that the injected DNA included sufficient cis-acting control elements for its tissue-specific and developmentally regulated expression in transgenic mice.


1997 ◽  
Vol 4 (2) ◽  
pp. 103-113 ◽  
Author(s):  
Sarn Jiralerspong ◽  
Yanling Liu ◽  
Laura Montermini ◽  
Stefano Stifani ◽  
Massimo Pandolfo

2003 ◽  
Vol 41 (11-12) ◽  
pp. 955-963 ◽  
Author(s):  
Tae-Seok Ko ◽  
Sangman Lee ◽  
Scott C. Schaefer ◽  
Schuyler S. Korban

2003 ◽  
Vol 133 (4) ◽  
pp. 1732-1746 ◽  
Author(s):  
Joseph A. Verica ◽  
Lee Chae ◽  
Hongyun Tong ◽  
Peter Ingmire ◽  
Zheng-Hui He

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