scholarly journals Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia

Development ◽  
2009 ◽  
Vol 136 (11) ◽  
pp. 1785-1789 ◽  
Author(s):  
Q. Schwarz ◽  
C. H. Maden ◽  
K. Davidson ◽  
C. Ruhrberg
Keyword(s):  
Neural Crest ◽  
Sensory Neurons ◽  
Dorsal Root Ganglia ◽  
Dorsal Root ◽  
Neural Crest Cell ◽  
Cell Guidance ◽  
Crest Cell

CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance

2014 ◽  
Vol 133 (8) ◽  
pp. 997-1009 ◽  
Author(s):  
Yvonne Schulz ◽  
Peter Wehner ◽  
Lennart Opitz ◽  
Gabriela Salinas-Riester ◽  
Ernie M. H. F. Bongers ◽  
...  
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Charge Syndrome ◽  
Cell Guidance ◽  
Crest Cell

Glutamate-immunoreactive sensory neurons in quail neural crest cell culture

1989 ◽  
Vol 497 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Rivka A. Rachel ◽  
Maya Sieber-Blum
Keyword(s):  
Cell Culture ◽  
Neural Crest ◽  
Sensory Neurons ◽  
Neural Crest Cell ◽  
Crest Cell

Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons

Development ◽  
1999 ◽  
Vol 126 (18) ◽  
pp. 3969-3979 ◽  
Author(s):  
K.B. Artinger ◽  
A.B. Chitnis ◽  
M. Mercola ◽  
W. Driever
Keyword(s):  
Neural Crest ◽  
Sensory Neurons ◽  
Cell Formation ◽  
Plate Boundary ◽  
Neural Crest Cell ◽  
Neural Crest Cells ◽  
Neural Plate ◽  
Crest Cell

In the developing vertebrate nervous system, both neural crest and sensory neurons form at the boundary between non-neural ectoderm and the neural plate. From an in situ hybridization based expression analysis screen, we have identified a novel zebrafish mutation, narrowminded (nrd), which reduces the number of early neural crest cells and eliminates Rohon-Beard (RB) sensory neurons. Mosaic analysis has shown that the mutation acts cell autonomously suggesting that nrd is involved in either the reception or interpretation of signals at the lateral neural plate boundary. Characterization of the mutant phenotype indicates that nrd is required for a primary wave of neural crest cell formation during which progenitors generate both RB sensory neurons and neural crest cells. Moreover, the early deficit in neural crest cells in nrd homozygotes is compensated later in development. Thus, we propose that a later wave can compensate for the loss of early neural crest cells but, interestingly, not the RB sensory neurons. We discuss the implications of these findings for the possibility that RB sensory neurons and neural crest cells share a common evolutionary origin.

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