scholarly journals Fgf8 is required for anterior heart field development

Development ◽  
2006 ◽  
Vol 133 (12) ◽  
pp. 2435-2445 ◽  
Author(s):  
R. Ilagan ◽  
R. Abu-Issa ◽  
D. Brown ◽  
Y.-P. Yang ◽  
K. Jiao ◽  
...  
2009 ◽  
Vol 104 (8) ◽  
pp. 933-942 ◽  
Author(s):  
Francesca Rochais ◽  
Karim Mesbah ◽  
Robert G. Kelly

Cell Research ◽  
2014 ◽  
Vol 24 (12) ◽  
pp. 1420-1432 ◽  
Author(s):  
Boon-Seng Soh ◽  
Kristina Buac ◽  
Huansheng Xu ◽  
Edward Li ◽  
Shi-Yan Ng ◽  
...  

Author(s):  
Christopher De Bono ◽  
Magali Théveniau-Ruissy ◽  
Robert G. Kelly

We focus on the origin of myocardial cells in the first and second heart fields in splanchnic mesoderm in the early embryo. Genetic lineage tracing using Cre recombinase activated conditional reporter genes has made a major contribution to our understanding of cardiac progenitor cells and will be discussed together with other experimental approaches to analysing cell lineages at the clonal level. Interactions between myocardial, epicardial and endocardial lineages are essential for coordinated function and homeostasis of the normal heart. Perturbation of heart field development and myocardial lineage contributions to the heart through developmental or acquired pathologies results in and modulates the progression of cardiac disease. Understanding the origin of myocardial lineages during embryonic development and how they converge to generate an integrated heart is thus a major biomedical objective. Furthermore, reactivation of developmental programmes is likely to be of major importance in strategies aimed at repair of the damaged heart.


2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Hagen R. Witzel ◽  
Sirisha Cheedipudi ◽  
Rui Gao ◽  
Didier Y. R. Stainier ◽  
Gergana D. Dobreva

2005 ◽  
Vol 287 (1) ◽  
pp. 134-145 ◽  
Author(s):  
Michael P. Verzi ◽  
David J. McCulley ◽  
Sarah De Val ◽  
Evdokia Dodou ◽  
Brian L. Black

Development ◽  
2010 ◽  
Vol 137 (18) ◽  
pp. 2989-3000 ◽  
Author(s):  
L. Tirosh-Finkel ◽  
A. Zeisel ◽  
M. Brodt-Ivenshitz ◽  
A. Shamai ◽  
Z. Yao ◽  
...  

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