scholarly journals Ligand Dissociation from Estrogen Receptor Is Mediated by Receptor Dimerization: Evidence from Molecular Dynamics Simulations

2008 ◽  
Vol 22 (7) ◽  
pp. 1565-1578 ◽  
Author(s):  
Milton T. Sonoda ◽  
Leandro Martínez ◽  
Paul Webb ◽  
Munir S. Skaf ◽  
Igor Polikarpov
Keyword(s):  
Molecular Dynamics ◽  
Estrogen Receptor ◽  
Molecular Dynamics Simulations ◽  
Receptor Dimerization ◽  
Ligand Dissociation ◽  
Dynamics Simulations

Activation helix orientation of the estrogen receptor is mediated by receptor dimerization: evidence from molecular dynamics simulations

2015 ◽  
Vol 17 (20) ◽  
pp. 13403-13420 ◽  
Author(s):  
Filip Fratev
Keyword(s):  
Molecular Dynamics ◽  
Estrogen Receptor ◽  
Molecular Dynamics Simulations ◽  
Dimer Formation ◽  
Receptor Dimerization ◽  
Helix 12 ◽  
Conformational Landscape ◽  
Helix Conformation ◽  
Helix Orientation ◽  
Dynamics Simulations

ERα dimer formation reshapes the helix 12 conformational landscape and is a leading factor for the activation helix conformation.

scholarly journals Molecular Dynamics Simulations Reveal Multiple Pathways of Ligand Dissociation from Thyroid Hormone Receptors

2005 ◽  
Vol 89 (3) ◽  
pp. 2011-2023 ◽  
Author(s):  
Leandro Martínez ◽  
Milton T. Sonoda ◽  
Paul Webb ◽  
John D. Baxter ◽  
Munir S. Skaf ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Thyroid Hormone ◽  
Molecular Dynamics Simulations ◽  
Hormone Receptors ◽  
Thyroid Hormone Receptors ◽  
Ligand Dissociation ◽  
Dynamics Simulations
Sign in / Sign up

Export Citation Format

Share Document