scholarly journals The Glucocorticoid Receptor and the Orphan Nuclear Receptor Chicken Ovalbumin Upstream Promoter-Transcription Factor II Interact with and Mutually Affect Each Other’s Transcriptional Activities: Implications for Intermediary Metabolism

2004 ◽  
Vol 18 (4) ◽  
pp. 820-833 ◽  
Author(s):  
Massimo U. De Martino ◽  
Nisan Bhattachryya ◽  
Salvatore Alesci ◽  
Takamasa Ichijo ◽  
George P. Chrousos ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Glucocorticoid Receptor ◽  
Nuclear Receptor ◽  
Intermediary Metabolism ◽  
Orphan Nuclear Receptor ◽  
Factor Ii ◽  
Upstream Promoter ◽  
Chicken Ovalbumin

scholarly journals Multiple Phosphorylation Events Control Chicken Ovalbumin Upstream Promoter Transcription Factor I Orphan Nuclear Receptor Activity

2002 ◽  
Vol 16 (6) ◽  
pp. 1332-1351 ◽  
Author(s):  
Frédérique Gay ◽  
Peter Baráth ◽  
Christine Desbois-Le Péron ◽  
Raphaël Métivier ◽  
Rémy Le Guével ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Nuclear Receptor ◽  
Receptor Activity ◽  
Orphan Nuclear Receptor ◽  
Factor I ◽  
Upstream Promoter ◽  
Chicken Ovalbumin

scholarly journals Recent progress on the role and molecular mechanism of chicken ovalbumin upstream promoter-transcription factor II in cancer

2020 ◽  
Vol 48 (4) ◽  
pp. 030006052091923
Author(s):  
Seong-Hoon Yun ◽  
Joo-In Park
Keyword(s):  
Transcription Factor ◽  
Recent Progress ◽  
Molecular Mechanisms ◽  
Orphan Receptor ◽  
Expression Of Genes ◽  
Factor Ii ◽  
Upstream Promoter ◽  
Cancer Types ◽  
Breast And Prostate Cancer ◽  
Chicken Ovalbumin

Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) is an orphan receptor that regulates the expression of genes involved in development and homeostasis. COUP-TFII is also dysregulated in cancer, where it plays important roles in oncogenesis and malignant progression. Recent studies have also investigated altered microRNA-mediated regulation of COUP-TFII in cancer. Although many investigators have studied the expression and clinical significance of COUP-TFII in several cancer types, there remain many controversies regarding its role in these diseases. In this review, we will describe the functions and underlying molecular mechanisms of COUP-TFII in several cancers, especially colorectal, gastric, breast, and prostate cancer; additionally, we will briefly summarize what is known about microRNA-mediated regulation of COUP-TFII.

Sign in / Sign up

Export Citation Format

Share Document