scholarly journals Correction for Xu et al., The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis

2008 ◽  
Vol 105 (23) ◽  
pp. 8161-8161
2002 ◽  
Vol 16 (6) ◽  
pp. 1332-1351 ◽  
Author(s):  
Frédérique Gay ◽  
Peter Baráth ◽  
Christine Desbois-Le Péron ◽  
Raphaël Métivier ◽  
Rémy Le Guével ◽  
...  

2020 ◽  
Vol 48 (4) ◽  
pp. 030006052091923
Author(s):  
Seong-Hoon Yun ◽  
Joo-In Park

Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) is an orphan receptor that regulates the expression of genes involved in development and homeostasis. COUP-TFII is also dysregulated in cancer, where it plays important roles in oncogenesis and malignant progression. Recent studies have also investigated altered microRNA-mediated regulation of COUP-TFII in cancer. Although many investigators have studied the expression and clinical significance of COUP-TFII in several cancer types, there remain many controversies regarding its role in these diseases. In this review, we will describe the functions and underlying molecular mechanisms of COUP-TFII in several cancers, especially colorectal, gastric, breast, and prostate cancer; additionally, we will briefly summarize what is known about microRNA-mediated regulation of COUP-TFII.


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