scholarly journals The Relationship between Body Mass Index and Thyroid Cancer Pathology Features and Outcomes: A Clinicopathological Cohort Study

2010 ◽  
Vol 95 (9) ◽  
pp. 4244-4250 ◽  
Author(s):  
John E. Paes ◽  
Keding Hua ◽  
Rebecca Nagy ◽  
Richard T. Kloos ◽  
David Jarjoura ◽  
...  
2020 ◽  
Author(s):  
Xiaokang Dong ◽  
Yuqian Li ◽  
Kaili Yang ◽  
Lulu Zhang ◽  
Yuan Xue ◽  
...  

Abstract Background: The relationship of spicy food intake with hyperuricemia remains unknow. The purpose of this study was to examine the association between spicy food intake and hyperuricemia, and whether this association was mediated by body mass index (BMI) in Chinese rural population.Methods: A total of 38, 027 adults, aged 18–79 years, were from the Henan Rural Cohort Study. Information on spicy food intake was obtained using a validated questionnaire survey. Multivariable logistic regression model was used to estimate the association between spicy food intake and hyperuricemia, multiple linear regression model was performed to estimate the relationships between spicy food intake, BMI and serum urate level. BMI was used as a mediator to estimate the mediation effect. Results: After adjusting for potential confounders, compared with no spicy food flavor, the odds ratio (OR) and 95% confidence interval (CI) of mild, middle, and heavy flavor for hyperuricemia was 1.09 (1.00-1.19), 1.10 (0.97-1.24), and 1.21 (1.10-1.46), respectively (Ptrend=0.017). Similarly, compared with no spicy food intake, the adjusted OR (95% CI) of 1 or 2days/week, 3-5 days/week, and 6 or 7 days/week were 1.15 (1.01-1.31), 1.14 (1.01-1.30) and 1.15 (1.05-1.26), respectively (Ptrend=0.007). Associations were substantially attenuated after additional control for BMI. Furthermore, mediation analysis showed that BMI play a full mediating role in the relationship between spicy food intake and hyperuricemia.Conclusion: Spicy food flavor and intake frequency is positively related with hyperuricemia in Chinese rural population. BMI may play a full mediating role in the relationship.


PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0190288 ◽  
Author(s):  
Marianne Bakke Johnsen ◽  
Alf Inge Hellevik ◽  
Milada Cvancarova Småstuen ◽  
Arnulf Langhammer ◽  
Ove Furnes ◽  
...  

2018 ◽  
Vol 7 (5) ◽  
pp. 2200-2210 ◽  
Author(s):  
Junya Sado ◽  
Tetsuhisa Kitamura ◽  
Tomotaka Sobue ◽  
Norie Sawada ◽  
Motoki Iwasaki ◽  
...  

2013 ◽  
Vol 74 (1) ◽  
pp. 235-242 ◽  
Author(s):  
Cari M. Kitahara ◽  
Michael Gamborg ◽  
Amy Berrington de González ◽  
Thorkild I.A. Sørensen ◽  
Jennifer L. Baker

2019 ◽  
Vol 27 (11) ◽  
pp. 1165-1174
Author(s):  
Lena Björck ◽  
Christina Lundberg ◽  
Maria Schaufelberger ◽  
Lauren Lissner ◽  
Martin Adiels ◽  
...  

Background The incidence of heart failure (HF) is decreasing in older ages, but increasing rates have been observed among younger persons in Sweden. Therefore, we investigated the relationship between risk of hospitalization for HF and body mass index (BMI). Methods This was a prospective registry-based cohort study. We included 1,374,031 women aged 18–45 years (mean age 27.9 years) who gave birth during 1982–2014, and were registered in the Medical Birth Register. Information on hospitalization because of HF was collected through linkage to the National Inpatient Register. Results Compared to women with a BMI of 20–<22.5 kg/m2, women with a BMI of 22.5–<25.0 had a hazard ratio (HR) of 1.24 (95% confidence interval (CI), 1.10–1.39) for HF after adjustment for age, year, parity, baseline disorders, smoking, and education. The HR (95% CI) increased to 1.56 (1.36–1.78), 2.39 (2.05–2.78), 2.82 (2.43–3.28), and 4.51 (3.63–5.61) in women with a BMI of 25–<27.5, 27.5–<30, 30–<35, and ≥35 kg/m2, respectively. The multiple-adjusted HRs (95% CI) associated with risk of HF per one-unit increase in BMI in women with a BMI ≥ 22.5 kg/m2 ranged from 1.01 (0.97–1.06) for HF related to valvular disease to 1.14 (1.12–1.15) for coronary heart disease, diabetes, or hypertension. Conclusion Increasing body weight was strongly associated with the risk of early HF in women. Compared with lean women, the risk for HF started to increase at high-normal BMI levels, and was nearly five-fold in women with a BMI ≥ 35 kg/m2.


1970 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
S Jahan ◽  
TR Das ◽  
KB Biswas

Background and Aims: Cord blood leptin may reflect the leptinemic status of a newborn at birth more accurately than the leptin values of blood collected from other sites. The present study was undertaken to determine the relationship of cord serum leptin concentration at birth with neonatal and maternal anthropometric parameters. Materials and Methods: Blood was taken from the umbilical cord of the babies at delivery. Maternal anthropometric measurements were recorded at admission for delivery. Neonatal anthropometric measurements were recorded within 48 hours after delivery. Linear regression analysis was used to explore the relationship between cord serum leptin concentration and anthropometric parameters of the baby and the mother. Both Serum leptin and serum C-peptide levels were measured by chemiluminescence-based ELISA method. Results: The leptin concentration (ng/ml, mean±SD) in cord blood was 39.13±14.44. Cord leptin levels correlated with birth weight (r=0.673, p<0.0001), ponderal index (r=0.732, p<0.0001) but it did not correlate with maternal body mass index, gestational age (r=0.135, p=0.349) at delivery or cord serum C-peptide concentration (r=-0.049, p=0.735) or placental weight (r=0.203, p=0.157). Conclusion: There are associations between cord leptin concentration at delivery and birth weight, ponderal index (PI) of the babies but not body mass index (BMI) of the mothers. High leptin levels of the baby could represent an important feedback modulator of substrate supply and subsequently for adipose tissue status during late gestation. (J Bangladesh Coll Phys Surg 2007; 25 : 9-13)


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