scholarly journals Interleukin-1β Stimulates Progesterone Production byin VitroHuman Luteal Cells: Evidence of a Mediatory Role of Prostaglandins

2003 ◽  
Vol 88 (6) ◽  
pp. 2690-2694 ◽  
Author(s):  
Fiorella Miceli ◽  
Anna Tropea ◽  
Francesca Minici ◽  
Pierluigi Navarra ◽  
Antonio Lanzone ◽  
...  
1989 ◽  
Vol 52 (6) ◽  
pp. 958-964 ◽  
Author(s):  
Ha-Lin C. Lee ◽  
Gary A. Shangold ◽  
Angela L. Larsen ◽  
James R. Schreiber

2011 ◽  
Vol 51 (2) ◽  
pp. 207-213 ◽  
Author(s):  
Toshiaki Taketani ◽  
Hiroshi Tamura ◽  
Akihisa Takasaki ◽  
Lifa Lee ◽  
Fumie Kizuka ◽  
...  

1997 ◽  
Vol 9 (6) ◽  
pp. 651 ◽  
Author(s):  
R. P. Del Vecchio ◽  
W. D. Sutherland

This experiment examined production of prostaglandin (PG) F2α , PGE2 and progesterone by bovine luteal cells incubated with or without the accessory cells and treated with recombinant bovine interleukin-1β (10 ng), indomethacin (5 µg) or luteinizing hormone (50 ng). During pretreatment, progesterone production was similar in the luteal and luteal plus accessory cells, being greater in either of these than in accessory cells; PGF2α was greatest in luteal plus accessory, intermediate in accessory and lowest in the luteal cells; PGE2 was similar among all cell arrangements. Luteinizing hormone or luteinizing hormone plus indomethacin stimulated progesterone in the luteal and luteal plus accessory cells, this being similar in these two cell arrangements. Interleukin-1β stimulated PGF2α in luteal and luteal plus accessory cells, and tended to elevate PGF2α in accessory cells. Interleukin-1β stimulated PGE2 in all cell arrangements. Indomethacin inhibited the interleukin-1b-stimulated PGF2α and PGE2 release. Indomethacin or indomethacin plus luteinizing hormone inhibited basal PGE2 in luteal and luteal plus accessory cells. These data suggest that progesterone production is not inßuenced by the presence of accessory cells of the corpus luteum, that accessory and luteal cells produce appreciable amounts of PG, and that recombinant bovine interleukin-1b stimulates PGE2 and PGF2α in the luteal and accessory cells.


1997 ◽  
Vol 56 (3) ◽  
pp. 663-667 ◽  
Author(s):  
James E. Young ◽  
Chad I. Friedman ◽  
Douglas R. Danforth

Circulation ◽  
1997 ◽  
Vol 96 (9) ◽  
pp. 3104-3111 ◽  
Author(s):  
Yoshihiro Fukumoto ◽  
Hiroaki Shimokawa ◽  
Toshiyuki Kozai ◽  
Toshiaki Kadokami ◽  
Kouichi Kuwata ◽  
...  

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