Dynamics of Magnetic Nanoparticles and Nanodevices

In this work, we demonstrate for the first time, a ferromagnetic resonance (FMR) based homogeneous and volumetric biosensor for magnetic label detection. Two different isothermal amplification methods, i.e., rolling circle amplification (RCA) and loop-mediated isothermal amplification (LAMP) are adopted and combined with a standard electron paramagnetic resonance (EPR) spectrometer for FMR biosensing. For RCA-based FMR biosensor, binding of RCA products of a synthetic Vibrio cholerae target DNA sequence gives rise to the formation of aggregates of magnetic nanoparticles. Immobilization of nanoparticles within the aggregates leads to a decrease of the net anisotropy of the system and a concomitant increase of the resonance field. A limit of detection of 1 pM is obtained with an average coefficient of variation of 0.16%, which is superior to the performance of other reported RCA-based magnetic biosensors. For LAMP-based sensing, a synthetic Zika virus target oligonucleotide is amplified and detected in 20% serum samples. Immobilization of magnetic nanoparticles is induced by their co-precipitation with Mg2P2O7 (a by-product of LAMP) and provides a detection sensitivity of 100 aM. The fast measurement, high sensitivity and miniaturization potential of the proposed FMR biosensing technology makes it a promising candidate for designing future point-of-care devices.

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Magnetic Nanoparticles for Extracting DNA from Blood Cells

Bulletin of the Russian Academy of Sciences Physics ◽

10.3103/s1062873820110155 ◽

2020 ◽

Vol 84 (11) ◽

pp. 1362-1365

Author(s):

A. V. Komina ◽

R. N. Yaroslavtsev ◽

Y. V. Gerasimova ◽

S. V. Stolyar ◽

I. A. Olkhovsky ◽

...

Keyword(s):

Magnetic Nanoparticles ◽

Blood Cells

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Magnetic Nanoparticles for Immobilization of Enzyme and their Applications - A Review

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2020.sp2.300 ◽

2020 ◽

Vol 12 (sp2) ◽

Keyword(s):

Magnetic Nanoparticles

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MR Molecular Imaging Based on Magnetic Nanoparticles

10.31916/sjmi.2018.01.01.17-28 ◽

2018 ◽

pp. 17-28

Author(s):

Hwunjae Lee ◽

◽

SangBock Lee ◽

Geahwan Jin ◽

Sergey NETESOV ◽

...

Keyword(s):

Magnetic Nanoparticles ◽

Molecular Imaging

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MR Molecular Imaging Based on Magnetic Nanoparticles

10.31916/sjmi.2018.01.01.17 ◽

2018 ◽

pp. 17-28

Author(s):

Hwunjae Lee ◽

◽

SangBock Lee ◽

Geahwan Jin ◽

Sergey NETESOV ◽

...

Keyword(s):

Magnetic Nanoparticles ◽

Molecular Imaging

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Formation of nanostructured magnetic films using layer-by-layer self-assembly of star polymers and magnetic nanoparticles

10.31979/etd.em8g-cwue ◽

2011 ◽

Author(s):

Shimul Shah

Keyword(s):

Magnetic Nanoparticles ◽

Self Assembly ◽

Star Polymers ◽

Magnetic Films ◽

Layer By Layer

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Faculty Opinions recommendation of Pollen magnetofection for genetic modification with magnetic nanoparticles as gene carriers.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732188264.793539724 ◽

2017 ◽

Author(s):

Luis Herrera-Estrella

Keyword(s):

Magnetic Nanoparticles ◽

Genetic Modification ◽

Gene Carriers

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INFLUENCE OF MAGNETIC NANOPARTICLES ON ACOUSTIC ATTENUATION IN LIQUIDS

Akustika ◽

10.36336/akustika2020378 ◽

2020 ◽

pp. 8-13

Author(s):

Štefan Hardoň ◽

Jozef Kúdelčík

Keyword(s):

Magnetic Nanoparticles ◽

Heat Exchangers ◽

Magnetic Fluids ◽

Magnetic Flux Density ◽

Acoustic Attenuation ◽

Cooling Systems ◽

Practical Applications ◽

Acoustic Spectroscopy ◽

Aggregation Processes ◽

Diagnostics And Therapy

Magnetic fluids with nanoparticles dispersed in water or oils offer attractive applications in biomedicine and industry. Biocompatible magnetic fluids are used for diagnostics and therapy in medical applications, in pharmacy, and biosensors. Application of ferrofluids is expanding into energy conservation, faster and efficient cooling, and hence better performance in a wide variety of practical applications (in heat exchangers, mainly in micro-cooling systems). For the study of the influence of an external magnetic field on the aggregation processes of magnetic nanoparticles in magnetic fluids, acoustic spectroscopy was used. The jump changes of the magnetic flux density at various temperatures influenced the acoustic attenuation. The measured changes were results of nanoparticle aggregations into new structures.

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