A highly sensitive new label-free bio-sensing platform using radio wave signal analysis, assisted by magnetic beads

2015 ◽  
pp. 155-158
2015 ◽  
Vol 3 (26) ◽  
pp. 5166-5171 ◽  
Author(s):  
Carmen C. Mayorga-Martinez ◽  
Alejandro Chamorro-García ◽  
Lorena Serrano ◽  
Lourdes Rivas ◽  
Daniel Quesada-Gonzalez ◽  
...  

A novel impedimetric label-free genosensor for highly sensitive DNA detection using a sensing platform based on thionine and iridium oxide nanoparticles.


RSC Advances ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 5714-5720 ◽  
Author(s):  
Xi Zhang ◽  
Na-Yan Xu ◽  
Qiong Ruan ◽  
Dan-Qing Lu ◽  
Yun-Hui Yang ◽  
...  

A highly sensitive luminescence sensor based on PLNPs for visualized detection of antibiotic and organic explosives was developed, which could eliminate the background interference, allowing low background and therefore high sensitivity.


RSC Advances ◽  
2018 ◽  
Vol 8 (29) ◽  
pp. 16146-16151 ◽  
Author(s):  
Keying Zhang ◽  
Na Zhang ◽  
Li Zhang ◽  
Hongyan Wang ◽  
Hongwei Shi ◽  
...  

A label-free impedimetric sensor for highly sensitive detection of miRNA-21 based on ZrO2-RGO nanocomposite and a catalytic hairpin assembly strategy.


Micromachines ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 147
Author(s):  
Kristina A. Malsagova ◽  
Tatyana O. Pleshakova ◽  
Vladimir P. Popov ◽  
Igor N. Kupriyanov ◽  
Rafael A. Galiullin ◽  
...  

Gas-phase etching and optical lithography were employed for the fabrication of a silicon nanoribbon chip (Si-NR chip). The quality of the so-fabricated silicon nanoribbons (Si-NRs) was monitored by optical Raman scattering spectroscopy. It was demonstrated that the structures of the Si-NRs were virtually defect-free, meaning they could be used for highly sensitive detection of biological macromolecules. The Si-NR chips were then used for the highly sensitive nanoelectronics detection of DNA oligonucleotides (oDNAs), which represent synthetic analogs of 106a-5p microRNA (miR-106a-5p), associated with the development of autism spectrum disorders in children. The specificity of the analysis was attained by the sensitization of the Si-NR chip sur-face by covalent immobilization of oDNA probes, whose nucleotide sequence was complementary to the known sequence of miR-106a-5p. The use of the Si-NR chip was demonstrated to al-low for the rapid label-free real-time detection of oDNA at ultra-low (~10−17 M) concentrations.


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