Analogies in the Adverse Immune Effects of Wear Particles, Environmental Particles, and Medicinal Nanoparticles

2014 ◽  
pp. 317-348
Author(s):  
Eleonore Fröhlich
Keyword(s):  
2019 ◽  
Vol 7 (SI-TeMIC18) ◽  
Author(s):  
Norhanifah Abdul Rahman ◽  
Matzaini Katon Katon ◽  
Nurina Alya Zulkifli Zulkifli

Automatic Transmission (AT) system is efficient in the aspects of vehicle safety, comfort, reliability and driving performance. The objectives of this paper are to collect the oil samples from AT systems of engine bus according to manufacturer's recommendations and analyse collected oil samples using oil analysis technique. The sample transmission fluid which was taken from the AT gearbox has been experimentally analyzed. The oil samples were taken with an interval of 5,000km, 30,000km, 50,000km, 80,000km, 180,000km and 300,000km for AT bus operation. These samples then have been analyzed by comparing between new and used transmission fluid using Fourier Transform Infrared (FTIR) spectroscopy. Oil analysis by FTIR is a form of Predictive Maintenance (PdM) to avoid major failure in machine elements. Most machine elements are not easily accessible in the transmission system. Having a reliable technique would avoid the needs to open the components unnecessarily, hence, help to prevent catastrophic failure which are very costly, and ease of regular monitoring. In order to identify the major failures of automatic gearbox, forecasts can be made regarding the lube transmission fluid analysis test. By using this test, the minor problems can be determined before they become major failures. At the end of this research, the wear particles profile for interval mileage of AT system was obtained. Keywords: Wear, Automatic Transmission (AT), Transmission fluid, Fourier Transform Infrared (FTIR), Oil analysis.


2018 ◽  
Author(s):  
Reto Gieré ◽  
◽  
Frank Sommer ◽  
Volker Dietze ◽  
Anja Baum ◽  
...  
Keyword(s):  

2020 ◽  
Vol 27 (15) ◽  
pp. 18345-18354 ◽  
Author(s):  
Lydia J. Knight ◽  
Florence N. F. Parker-Jurd ◽  
Maya Al-Sid-Cheikh ◽  
Richard C. Thompson
Keyword(s):  

Friction ◽  
2021 ◽  
Author(s):  
Xiaobin Hu ◽  
Jian Song ◽  
Zhenhua Liao ◽  
Yuhong Liu ◽  
Jian Gao ◽  
...  

AbstractFinding the correct category of wear particles is important to understand the tribological behavior. However, manual identification is tedious and time-consuming. We here propose an automatic morphological residual convolutional neural network (M-RCNN), exploiting the residual knowledge and morphological priors between various particle types. We also employ data augmentation to prevent performance deterioration caused by the extremely imbalanced problem of class distribution. Experimental results indicate that our morphological priors are distinguishable and beneficial to largely boosting overall performance. M-RCNN demonstrates a much higher accuracy (0.940) than the deep residual network (0.845) and support vector machine (0.821). This work provides an effective solution for automatically identifying wear particles and can be a powerful tool to further analyze the failure mechanisms of artificial joints.


2012 ◽  
Vol 23 (4) ◽  
pp. 891-901 ◽  
Author(s):  
Fang Lu ◽  
Matt Royle ◽  
Ferdinand V. Lali ◽  
Alister J. Hart ◽  
Simon Collins ◽  
...  

Antibiotics ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 346
Author(s):  
Bernd Fink ◽  
Marius Hoyka ◽  
Elke Weissbarth ◽  
Philipp Schuster ◽  
Irina Berger

Aim: This study was designed to answer the question whether a graphical representation increase the diagnostic value of automated leucocyte counting of the synovial fluid in the diagnosis of periprosthetic joint infections (PJI). Material and methods: Synovial aspirates from 322 patients (162 women, 160 men) with revisions of 192 total knee and 130 hip arthroplasties were analysed with microbiological cultivation, determination of cell counts and assay of the biomarker alpha-defensin (170 cases). In addition, microbiological and histological analysis of the periprosthetic tissue obtained during the revision surgery was carried out using the ICM classification and the histological classification of Morawietz and Krenn. The synovial aspirates were additionally analysed to produce dot plot representations (LMNE matrices) of the cells and particles in the aspirates using the hematology analyser ABX Pentra XL 80. Results: 112 patients (34.8%) had an infection according to the ICM criteria. When analysing the graphical LMNE matrices from synovia cell counting, four types could be differentiated: the type “wear particles” (I) in 28.3%, the type “infection” (II) in 24.8%, the “combined” type (III) in 15.5% and “indeterminate” type (IV) in 31.4%. There was a significant correlation between the graphical LMNE-types and the histological types of Morawietz and Krenn (p < 0.001 and Cramer test V value of 0.529). The addition of the LMNE-Matrix assessment increased the diagnostic value of the cell count and the cut-off value of the WBC count could be set lower by adding the LMNE-Matrix to the diagnostic procedure. Conclusion: The graphical representation of the cell count analysis of synovial aspirates is a new and helpful method for differentiating between real periprosthetic infections with an increased leukocyte count and false positive data resulting from wear particles. This new approach helps to increase the diagnostic value of cell count analysis in the diagnosis of PJI.


2021 ◽  
pp. 111727
Author(s):  
Anna M. O'Brien ◽  
Tiago F. Lins ◽  
Yaming Yang ◽  
Megan E. Frederickson ◽  
David Sinton ◽  
...  

2021 ◽  
pp. 110668
Author(s):  
Eben G. Estell ◽  
Lance A. Murphy ◽  
Lianna R. Gangi ◽  
Roshan P. Shah ◽  
Gerard A. Ateshian ◽  
...  

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