Role of Fluid Dynamics in Dreissenid Mussel Biology

2013 ◽  
pp. 471-484 ◽  
Author(s):  
Josef Ackerman
2015 ◽  
Vol 56 (11) ◽  
pp. 6630 ◽  
Author(s):  
Peter Wostyn ◽  
Veva De Groot ◽  
Debby Van Dam ◽  
Kurt Audenaert ◽  
Hanspeter Esriel Killer ◽  
...  

2011 ◽  
pp. 794-806
Author(s):  
Dolores A. Steinman ◽  
David A. Steinman

In the following chapter, the authors will discuss the development of medical imaging and, through specific case studies, its application in elucidating the role of fluid mechanical forces in cardiovascular disease development and therapy (namely the connection between flow patterns and circulatory system disease - atherosclerosis and aneurysms) by means of computational fluid dynamics (CFD). The research carried in the Biomedical Simulation Laboratory can be described as a multi-step process through which, from the reality of the human body through the generation of a mathematical model that is then translated into a visual representation, a refined visual representation easily understandable and used in the clinic is generated. Thus, the authors’ daily research generates virtual representations of blood flow that can serve two purposes: a) that of a model for a phenomenon or disease or b) that of a model for an experiment (non-invasive way of determining the best treatment option).


Author(s):  
Siyeong Ju ◽  
Linxia Gu

Stenosis or narrowing of arteries induces a turbulent flow region downstream. Multiple stenosis may lead to flow interference and further disturb the blood flow. This has important clinical implications [1], such as disturbed blood flow and flow recirculation which were correlated with the development of atherosclerosis by upregulating the endothelial cells genes and proteins that cause atherogenesis [2]. Numerical simulation of concentric stenoses by Lee et al [3] have shown that the recirculation zone following the first concentric stenosis affected the flow field at the downstream of the second one, which was dependent on the spacing ratio and degree of stenosis. However, the majority of stenosis is eccentric [2] and the detailed fluid dynamics of multiple stenoses with eccentric constrictions is lacking. The aim of this study is to investigate the interactions between double stenoses with eccentricity using computational fluid dynamics (CFD) simulation. The role of spacing ratio on the recirculation zone and turbulence intensity (TI) were characterized and also compared to concentric cases.


2012 ◽  
Vol 26 (5) ◽  
pp. 2786-2797 ◽  
Author(s):  
Stefan Hjärtstam ◽  
Robert Johansson ◽  
Klas Andersson ◽  
Filip Johnsson

1991 ◽  
Vol 3 (5) ◽  
pp. 1456-1456
Author(s):  
R. Oliver ◽  
J. G. B. Smith

Author(s):  
Dario Collia ◽  
Luigino Zovatto ◽  
Giovanni Tonti ◽  
Gianni Pedrizzetti

The right and left sides of the human heart operate with a common timing and pump the same amount of blood. Therefore, the right ventricle (RV) presents a function that is comparable to the left ventricle (LV) in terms of flow generation; nevertheless, the RV operates against a much lower arterial pressure (afterload) and requires a lower muscular strength. This study compares the fluid dynamics of the normal right and left ventricles to better understand the role of the RV streamlined geometry and provide some physics-based ground for the construction of clinical indicators for the right side. The analysis is performed by image-based direct numerical simulation, using the immersed boundary technique including the simplified models of tricuspid and mitral valves. Results demonstrated that the vortex formation process during early diastole is similar in the two ventricles, then the RV vorticity rapidly dissipates in the subvalvular region while the LV sustains a weak circulatory pattern at the center of the chamber. Afterwards, during the systolic contraction, the RV geometry allows an efficient transfer of mechanical work to the propelled blood; differently from the LV, this work is non-negligible in the global energetic balance. The varying behavior of the RV, from reservoir to conduct, during the different phases of the heartbeat is briefly discussed in conjunction to the development of possible dysfunctions.


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