- Multi-Modal Tomography Combining Optical Coherence Tomography (OCT) with Fluorescence Laminar Optical Tomography (FLOT)

2016 ◽  
pp. 319-340
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Tomography ◽  
Optical Coherence

Optical Biopsy of Lymph Node Morphology using Optical Coherence Tomography

2005 ◽  
Vol 4 (5) ◽  
pp. 539-547 ◽  
Author(s):  
Wei Luo ◽  
Freddy T. Nguyen ◽  
Adam M. Zysk ◽  
Tyler S. Ralston ◽  
John Brockenbrough ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Lymph Node ◽  
High Resolution ◽  
Breast Imaging ◽  
Optical Tomography ◽  
Screening Method ◽  
Optical Biopsy ◽  
Infrared Light ◽  
Optical Coherence ◽  
Cross Sectional

Optical diagnostic imaging techniques are increasingly being used in the clinical environment, allowing for improved screening and diagnosis while minimizing the number of invasive procedures. Diffuse optical tomography, for example, is capable of whole-breast imaging and is being developed as an alternative to traditional X-ray mammography. While this may eventually be a very effective screening method, other optical techniques are better suited for imaging on the cellular and molecular scale. Optical Coherence Tomography (OCT), for instance, is capable of high-resolution cross-sectional imaging of tissue morphology. In a manner analogous to ultrasound imaging except using optics, pulses of near-infrared light are sent into the tissue while coherence-gated reflections are measured interferometrically to form a cross-sectional image of tissue. In this paper we apply OCT techniques for the high-resolution three-dimensional visualization of lymph node morphology. We present the first reported OCT images showing detailed morphological structure and corresponding histological features of lymph nodes from a carcinogen-induced rat mammary tumor model, as well as from a human lymph node containing late stage metastatic disease. The results illustrate the potential for OCT to visualize detailed lymph node structures on the scale of micrometastases and the potential for the detection of metastatic nodal disease intraoperatively.

scholarly journals Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography

2016 ◽  
Vol 7 (12) ◽  
pp. 5218 ◽  
Author(s):  
Qinggong Tang ◽  
Jianting Wang ◽  
Aaron Frank ◽  
Jonathan Lin ◽  
Zhifang Li ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Tomography ◽  
Colon Tumor ◽  
Optical Coherence

scholarly journals Orbital Cavernous Hemangioma Presenting with a Dome-Shaped Maculopathy-Like Appearance on Swept-Source Optical Tomography Imaging

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Şükran Bekdemir ◽  
Ahmet Kaan Gündüz ◽  
Cevriye Cansız Ersöz
Keyword(s):  
Optical Coherence Tomography ◽  
Cavernous Hemangioma ◽  
Vision Loss ◽  
Optical Tomography ◽  
Posterior Pole ◽  
Optical Coherence ◽  
Swept Source ◽  
Choroidal Vasculature ◽  
Funduscopic Examination ◽  
The Right

A 43-year-old patient presented with painless proptosis, limited upgaze, and vision loss in the right eye. Funduscopic examination revealed right optic disc edema and subtle macular compression. Swept-source optical coherence tomography (SS-OCT) revealed a smooth contoured elevation of the posterior pole without any distortion of retinal structures, an appearance closely simulating dome-shaped maculopathy. Swept-source optical coherence tomography angiography (SS-OCTA) revealed normal retinal and choroidal vasculature. Orbital magnetic resonance imaging demonstrated a well-circumscribed intraconal mass compressing the globe and optic nerve in the right orbit. An anterior orbitotomy was performed, whereby the tumor was totally excised and diagnosed histopathologically as cavernous hemangioma. This case represents an orbital cavernous hemangioma touching the eyeball and producing compression of the posterior pole presenting with a dome-shaped maculopathy-like appearance on SS-OCT. SS-OCT and SS-OCTA are important noninvasive tools for evaluating the retinal and choroidal effects in orbital tumors.

Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT)

2010 ◽  
Vol 16 (4) ◽  
pp. 755-766 ◽  
Author(s):  
Yu Chen ◽  
Shuai Yuan ◽  
Jeremiah Wierwille ◽  
Renee Naphas ◽  
Qian Li ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Tomography ◽  
Optical Coherence ◽  
Integrated Optical
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