Long-term risks after living kidney donation

2005 ◽  
pp. 111-124
Keyword(s):  
Kidney Donation ◽  
Living Kidney Donation

Long term risk of mortality after living kidney donation

BMJ ◽  
2017 ◽  
pp. j1770
Author(s):  
Geir Mjøen ◽  
Hallvard Holdaas
Keyword(s):  
Kidney Donation ◽  
Living Kidney Donation ◽  
Risk Of Mortality

scholarly journals Long-term outcome of living kidney donation

2015 ◽  
Vol 29 (1) ◽  
pp. 129-131 ◽  
Author(s):  
Luigi Biancone ◽  
Emanuele Cozzi ◽  
Marta López-Fraga ◽  
Alessandro Nanni-Costa
Keyword(s):  
Kidney Donation ◽  
Living Kidney Donation ◽  
Term Outcome ◽  
Long Term Outcome

scholarly journals Self-Reported Incident Hypertension and Long-Term Kidney Function in Living Kidney Donors Compared with Healthy Nondonors

2019 ◽  
Vol 14 (10) ◽  
pp. 1493-1499 ◽  
Author(s):  
Courtenay M. Holscher ◽  
Christine E. Haugen ◽  
Kyle R. Jackson ◽  
Jacqueline M. Garonzik Wang ◽  
Madeleine M. Waldram ◽  
...  
Keyword(s):  
Kidney Donation ◽  
Living Kidney Donation ◽  
Kidney Donors ◽  
Incident Hypertension ◽  
Living Kidney Donors ◽  
Parametric Survival Model ◽  
Yearly Change ◽  
Parametric Survival ◽  
Multilevel Linear Regression

Background and objectivesThe risk of hypertension attributable to living kidney donation remains unknown as does the effect of developing postdonation hypertension on subsequent eGFR. We sought to understand the association between living kidney donation, hypertension, and long-term eGFR by comparing donors with a cohort of healthy nondonors.Design, setting, participants, & measurementsWe compared 1295 living kidney donors with median 6 years of follow-up with a weighted cohort of 8233 healthy nondonors. We quantified the risk of self-reported hypertension using a parametric survival model. We examined the association of hypertension with yearly change in eGFR using multilevel linear regression and clustering by participant, with an interaction term for race.ResultsKidney donation was independently associated with a 19% higher risk of hypertension (adjusted hazard ratio, 1.19; 95% confidence interval, 1.01 to 1.41; P=0.04); this association did not vary by race (interaction P=0.60). For white and black nondonors, there was a mean decline in eGFR (−0.4 and −0.3 ml/min per year, respectively) that steepened after incident hypertension (−0.8 and −0.9 ml/min per year, respectively; both P<0.001). For white and black kidney donors, there was a mean increase in eGFR after donation (+0.4 and +0.6 ml/min per year, respectively) that plateaued after incident hypertension (0 and −0.2 ml/min per year, respectively; P=0.07 and P=0.01, respectively, after hypertension).ConclusionsKidney donors are at higher risk of hypertension than similar healthy nondonors, regardless of race. Donors who developed hypertension had a plateau in the usual postdonation increase of eGFR.

Long-term Safety of Living Kidney Donation in an Emerging Economy

2016 ◽  
Vol 100 (6) ◽  
pp. 1284-1293 ◽  
Author(s):  
S. Adibul Hasan Rizvi ◽  
Mirza Naqi Zafar ◽  
Fatema Jawad ◽  
Tahir Aziz ◽  
Zafar Hussain ◽  
...  
Keyword(s):  
Emerging Economy ◽  
Kidney Donation ◽  
Living Kidney Donation
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