Seoul Virus

2016 ◽  
pp. 731-738
Keyword(s):  
2017 ◽  
Vol 66 (40) ◽  
pp. 1081-1082 ◽  
Author(s):  
Mary-Margaret A. Fill ◽  
Heather Mullins ◽  
Andrew Stephen May ◽  
Heather Henderson ◽  
Shelley M. Brown ◽  
...  
Keyword(s):  

2018 ◽  
Vol 24 (6) ◽  
pp. 1099-1102 ◽  
Author(s):  
Jörg Hofmann ◽  
Sabrina Weiss ◽  
Martin Kuhns ◽  
Annekathrin Zinke ◽  
Heike Heinsberger ◽  
...  
Keyword(s):  

Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 531 ◽  
Author(s):  
Miriam Maas ◽  
Melanie van Heteren ◽  
Ankje de Vries ◽  
Thijs Kuiken ◽  
Tabitha Hoornweg ◽  
...  

Seoul virus (SEOV) is a zoonotic orthohantavirus carried by black and brown rats, and can cause hemorrhagic fever with renal syndrome in humans. Human cases of SEOV virus infection have most recently been reported in the USA, United Kingdom, France and the Netherlands and were primarily associated with contact with pet rats and feeder rats. Infection of rats results in an asymptomatic but persistent infection. Little is known about the cell tropism of SEOV in its reservoir and most available data is based on experimental infection studies in which rats were inoculated via a route which does not recapitulate virus transmission in nature. Here we report the histopathological analysis of SEOV cell tropism in key target organs following natural infection of a cohort of feeder rats, comprising 19 adults and 11 juveniles. All adult rats in this study were positive for SEOV specific antibodies and viral RNA in their tissues. One juvenile rat was seropositive, but negative in the rRT-PCR. Of the 19 adult rats of which subsequently additional organs were tested, SEOV RNA was detected in all lungs, followed by kidney (79%) and liver (74%). Histopathologic changes associated with SEOV infection were primarily found in the liver, consistent with a pathological diagnosis of a mild hepatitis. In conclusion, natural SEOV infection results in mild inflammation of the liver in the absence of clinical disease.


2017 ◽  
Vol 17 (6) ◽  
pp. 425-431 ◽  
Author(s):  
Xi-Feng Sun ◽  
Li Zhao ◽  
Zhen-Tang Zhang ◽  
Miao-Miao Liu ◽  
Zai-Feng Xue ◽  
...  

2017 ◽  
Vol 32 (3) ◽  
pp. 235-244 ◽  
Author(s):  
Dong-Ying Liu ◽  
Jing Liu ◽  
Bing-Yu Liu ◽  
Yuan-Yuan Liu ◽  
Hai-Rong Xiong ◽  
...  

2012 ◽  
Vol 141 (9) ◽  
pp. 1876-1884 ◽  
Author(s):  
T. KOMA ◽  
K. YOSHIMATSU ◽  
S. P. YASUDA ◽  
T. LI ◽  
T. AMADA ◽  
...  

SUMMARYTo examine the prevalence of human pathogens carried by rats in urban areas in Hanoi and Hai Phong, Vietnam, we live-trapped 100 rats in January 2011 and screened them for a panel of bacteria and viruses. Antibodies againstLeptospira interrogans(22·0%), Seoul virus (14·0%) and rat hepatitis E virus (23·0%) were detected in rats, but antibodies againstYersinia pestiswere not detected. Antibodies againstL. interrogansand Seoul virus were found only in adult rats. In contrast, antibodies to rat hepatitis E virus were also found in juvenile and sub-adult rats, indicating that the transmission mode of rat hepatitis E virus is different from that ofL. interrogansand Seoul virus. Moreover, phylogenetic analyses of the S and M segments of Seoul viruses found inRattus norvegicusshowed that Seoul viruses from Hai Phong and Hanoi formed different clades. Human exposure to these pathogens has become a significant public health concern.


2013 ◽  
Vol 19 (11) ◽  
Author(s):  
Lisi Yao ◽  
Zhehao Kang ◽  
Yongxian Liu ◽  
Fenglin Song ◽  
Xiaolong Zhang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document