Platinum(IV) Anticancer Complexes

2004 ◽  
pp. 297-322 ◽  
Author(s):  
Matthew D. Hall ◽  
Rachael C. Dolman ◽  
Trevor W. Hambley
Keyword(s):  
Anticancer Complexes

Potent Half-Sandwich Iridium(III) and Ruthenium(II) Anticancer Complexes Containing a P^O-Chelated Ligand

2018 ◽  
Vol 37 (17) ◽  
pp. 2880-2889 ◽  
Author(s):  
Qing Du ◽  
Lihua Guo ◽  
Meng Tian ◽  
Xingxing Ge ◽  
Yuliang Yang ◽  
...  
Keyword(s):  
Anticancer Complexes ◽  
Half Sandwich

Basis for Design and Development of Platinum(IV) Anticancer Complexes

2007 ◽  
Vol 50 (15) ◽  
pp. 3403-3411 ◽  
Author(s):  
Matthew D. Hall ◽  
Howard R. Mellor ◽  
Richard Callaghan ◽  
Trevor W. Hambley
Keyword(s):  
Design And Development ◽  
Anticancer Complexes

ChemInform Abstract: Synthetic Methods for the Preparation of Platinum Anticancer Complexes

ChemInform ◽  
2014 ◽  
Vol 45 (24) ◽  
pp. no-no
Author(s):  
Justin J. Wilson ◽  
Stephen J. Lippard
Keyword(s):  
Synthetic Methods ◽  
Anticancer Complexes

scholarly journals Sequence-dependent attack on peptides by photoactivated platinum anticancer complexes

2018 ◽  
Vol 9 (10) ◽  
pp. 2733-2739 ◽  
Author(s):  
Christopher A. Wootton ◽  
Carlos Sanchez-Cano ◽  
Andrea F. Lopez-Clavijo ◽  
Evyenia Shaili ◽  
Mark P. Barrow ◽  
...  
Keyword(s):  
Amino Acid ◽  
Visible Light ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Sequence Dependent ◽  
Anticancer Complexes

Octahedral anticancer platinum(iv) complexes such as trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2] (1) can target peptides (and proteins) by sequence-dependent platination and radical mechanisms when activated by UVA or visible light; the specific products are highly dependent on their amino acid composition of the peptide.

Rhodamine-modified fluorescent half-sandwich iridium and ruthenium complexes: potential application as bioimaging and anticancer agents

2019 ◽  
Vol 48 (15) ◽  
pp. 4788-4793 ◽  
Author(s):  
Wenli Ma ◽  
Lihua Guo ◽  
Zhenzhen Tian ◽  
Shumiao Zhang ◽  
Xiangdong He ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Anticancer Agents ◽  
Potential Application ◽  
Ruthenium Complexes ◽  
Anticancer Complexes ◽  
Half Sandwich

Most half-sandwich metal anticancer complexes are non-fluorescent, which results in an uncertain mechanism of action (MoA).

scholarly journals Monofunctional platinum(ii) anticancer complexes based on multidentate phenanthridine-containing ligand frameworks

2020 ◽  
Vol 49 (20) ◽  
pp. 6557-6560 ◽  
Author(s):  
Issiah B. Lozada ◽  
Bin Huang ◽  
Morgan Stilgenbauer ◽  
Travis Beach ◽  
Zihan Qiu ◽  
...  
Keyword(s):  
Therapeutic Index ◽  
Multidentate Ligands ◽  
Anticancer Complexes

Pt(ii) complexes supported by chelating, multidentate ligands containing phenanthridine heterocycles are reported and shown to exhibit a superior in vitro therapeutic index compared with phenanthriplatin and cisplatin.

scholarly journals Exploring Ovarian Cancer Cell Resistance to Rhenium Anticancer Complexes

2020 ◽  
Vol 132 (32) ◽  
pp. 13493-13502 ◽  
Author(s):  
Sierra C. Marker ◽  
A. Paden King ◽  
Robert V. Swanda ◽  
Brett Vaughn ◽  
Eszter Boros ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Cell Resistance ◽  
Anticancer Complexes
Sign in / Sign up

Export Citation Format

Share Document