Self-Healing of Gold Nanoparticles during Laser Irradiation: An Embryonic Case of “Systems Nanotechnology”

2011 ◽  
pp. 96-115
2018 ◽  
Vol 20 (45) ◽  
pp. 28465-28475 ◽  
Author(s):  
Collin J. Rodrigues ◽  
Julian A. Bobb ◽  
Mallory G. John ◽  
Sergey P. Fisenko ◽  
M. Samy El-Shall ◽  
...  

Irradiation of aqueous [AuCl4]− with 532 nm, 8 ns pulses produces uniform 5 nm Au nanoparticles through surface plasmon-mediated photothermal autocatalytic growth, in contrast to the large polydisperse particles formed with 800 nm, 30 fs pulses.


2020 ◽  
Vol 11 (13) ◽  
pp. 5108-5114 ◽  
Author(s):  
Juan Carlos Castro-Palacio ◽  
Konstantin Ladutenko ◽  
Alejandro Prada ◽  
Guillermo González-Rubio ◽  
Pablo Díaz-Núñez ◽  
...  

2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Pedro Pedrosa ◽  
Amelie Heuer-Jungemann ◽  
Antonios G. Kanaras ◽  
Alexandra R. Fernandes ◽  
Pedro V. Baptista

2006 ◽  
Vol 6 (1) ◽  
pp. 130-134 ◽  
Author(s):  
Olivier Balmes ◽  
Jan-Olov Bovin ◽  
Jan-Olle Malm

Gold nanoparticles (5 nm and 20 nm) have been synthesized and stabilized with mercaptoundecanol. These particles, although insoluble in water or common organic solvents, spread as a thin film at the liquid–liquid interface between a water phase and an organic phase. Films of these gold nanoparticles have been observed both by conventional transmission electron microscopy of deposited samples and by cryo-transmission electron microscopy of plunge-frozen samples. The film can be monolayered and extend over centimeter-sized areas. The particle films spontaneously re-assemble and self-organize at the interface when disrupted. This self-healing capacity of the film should make it possible to build a device for continuous production and deposition of the film.


2020 ◽  
Vol 10 (11) ◽  
pp. 1950-1959
Author(s):  
Lei Yang ◽  
Yumin Hu ◽  
Yuanfen Liu ◽  
Yanyan Liu ◽  
Si Miao ◽  
...  

The treatment of malignant bone tumors (including primary bone tumors and metastatic bone tumors) has always been a clinical challenge. The purpose of this study is to design a bone-targeted nano-carrier with photothermal effect to achieve chemo-photothermal therapy (CPT), which allows the minimal use of photothermal agents and chemical drugs to target bone tumors. Alendronate modified hollow gold nanoparticles (HGNPs- ALN) were synthesized using mercapto polyethylene glycol carboxyl (SH-PEG2000-COOH) as the connecting arm, fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM) data show that HGNPs-ALN with a particle size of about 80 nm has been successfully synthesized. The hydroxyapatite affinity experiment in vitro indicated that HGNPs-ALN exhibited a high affinity to bone. In addition, the temperature of HGNPs-ALN under near-infrared laser irradiation can rise to 53 °C, which can achieve effective photothermal therapy for bone tumors. Bone-targeted hollow gold nanoparticles (DOX@HGNPs-ALN) loaded with doxorubicin hydrochloride (DOX) were synthesized by one-pot method. By comparing the stability and drug loading of HGNPs-ALN, it was concluded that the optimal mass ratio of HGNPs-ALN (calculated by the amount of gold) to DOX was about 1:2. HGNPs-ALN and DOX@HGNPs-ALN both have good photothermal stability and photothermal transformation properties, and confirmed the safety of HGNPs on human osteosarcoma cells. MTT experiments showed that DOX@HGNPs-ALN had the strongest killing effect on MG-63 osteosarcoma cells under laser irradiation (the killing rate is about 65%). According to these results, it can be considered that DOX@HGNPs-ALN has the potential of CPT synergistic targeting therapy for bone tumors.


2012 ◽  
Vol 116 (4) ◽  
pp. 2647-2655 ◽  
Author(s):  
Chaxing Fan ◽  
Bertrand Poumellec ◽  
Huidan Zeng ◽  
Rudy Desmarchelier ◽  
Bernard Bourguignon ◽  
...  

2010 ◽  
Vol 289 (5-6) ◽  
pp. 583-590 ◽  
Author(s):  
Chan Woo Park ◽  
Antoinette B. South ◽  
Xiaobo Hu ◽  
Claudia Verdes ◽  
Jong-Duk Kim ◽  
...  

2010 ◽  
Vol 64 (11) ◽  
pp. 1279-1282 ◽  
Author(s):  
Hicham El Hamzaoui ◽  
Rémy Bernard ◽  
Abdallah Chahadih ◽  
Fernand Chassagneux ◽  
Laurence Bois ◽  
...  

2015 ◽  
Author(s):  
Olga Bibikova ◽  
Prateek Singh ◽  
Alexey Popov ◽  
Georgy Akchurin ◽  
Ilya Skovorodkin ◽  
...  

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