Microanalysis and Macroanalysis of High-Frequency Oscillations in the Human Brain

Epilepsy ◽  
2011 ◽  
pp. 369-381 ◽  
Author(s):  
B Crépon ◽  
M Valderrama ◽  
C Alvarado-Rojas ◽  
V Navarro ◽  
M Le Van Quyen
Keyword(s):  
Human Brain ◽  
High Frequency ◽  
High Frequency Oscillations

scholarly journals Recent advances in the noninvasive detection of high-frequency oscillations in the human brain

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Yuying Fan ◽  
Liping Dong ◽  
Xueyan Liu ◽  
Hua Wang ◽  
Yunhui Liu
Keyword(s):  
Human Brain ◽  
Clinical Research ◽  
High Frequency ◽  
Signal To Noise Ratio ◽  
Detection Methods ◽  
Clinical Settings ◽  
Multicenter Studies ◽  
High Frequency Oscillations ◽  
Seizure Onset Zone ◽  
Clinical Literature

Abstract In recent decades, a significant body of evidence based on invasive clinical research has showed that high-frequency oscillations (HFOs) are a promising biomarker for localization of the seizure onset zone (SOZ), and therefore, have the potential to improve postsurgical outcomes in patients with epilepsy. Emerging clinical literature has demonstrated that HFOs can be recorded noninvasively using methods such as scalp electroencephalography (EEG) and magnetoencephalography (MEG). Not only are HFOs considered to be a useful biomarker of the SOZ, they also have the potential to gauge disease severity, monitor treatment, and evaluate prognostic outcomes. In this article, we review recent clinical research on noninvasively detected HFOs in the human brain, with a focus on epilepsy. Noninvasively detected scalp HFOs have been investigated in various types of epilepsy. HFOs have also been studied noninvasively in other pathologic brain disorders, such as migraine and autism. Herein, we discuss the challenges reported in noninvasive HFO studies, including the scarcity of MEG and high-density EEG equipment in clinical settings, low signal-to-noise ratio, lack of clinically approved automated detection methods, and the difficulty in differentiating between physiologic and pathologic HFOs. Additional studies on noninvasive recording methods for HFOs are needed, especially prospective multicenter studies. Further research is fundamental, and extensive work is needed before HFOs can routinely be assessed in clinical settings; however, the future appears promising.

High-frequency oscillations in human brain

Hippocampus ◽  
1999 ◽  
Vol 9 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Anatol Bragin ◽  
Jerome Engel ◽  
Charles L. Wilson ◽  
Itzhak Fried ◽  
Gyorgy Buzs�ki
Keyword(s):  
Human Brain ◽  
High Frequency ◽  
High Frequency Oscillations

High-Frequency Oscillations in the Normal Human Brain

2018 ◽  
Vol 84 (3) ◽  
pp. 374-385 ◽  
Author(s):  
Birgit Frauscher ◽  
Nicolás von Ellenrieder ◽  
Rina Zelmann ◽  
Christine Rogers ◽  
Dang Khoa Nguyen ◽  
...  
Keyword(s):  
Human Brain ◽  
High Frequency ◽  
Normal Human Brain ◽  
High Frequency Oscillations ◽  
Normal Human

scholarly journals Can we use intraoperative high‐frequency oscillations to guide tumor‐related epilepsy surgery?

Epilepsia ◽  
2021 ◽  
Author(s):  
Nicole E. C. Klink ◽  
Willemiek J. E. M. Zweiphenning ◽  
Cyrille H. Ferrier ◽  
Peter H. Gosselaar ◽  
Kai J. Miller ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
High Frequency ◽  
High Frequency Oscillations
Sign in / Sign up

Export Citation Format

Share Document