Toxic effects of arsenic on human erythrocytes

2010 ◽  
pp. 37-46 ◽  
Author(s):  
Mario Suwalsky ◽  
Cecilia Rivera ◽  
Fernando Villena ◽  
Carlos Sotomayor
Keyword(s):  
Human Erythrocytes ◽  
Toxic Effects

Toxic effects of the anticancer drug epirubicin in vitro assayed in human erythrocytes

2020 ◽  
Vol 68 ◽  
pp. 104964
Author(s):  
Karla Petit ◽  
Mario Suwalsky ◽  
José R. Colina ◽  
David Contreras ◽  
Luis F. Aguilar ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Human Erythrocytes ◽  
Toxic Effects

Cytochrome P450-dependent toxic effects of primaquine on human erythrocytes

2009 ◽  
Vol 241 (1) ◽  
pp. 14-22 ◽  
Author(s):  
Shobana Ganesan ◽  
Babu L. Tekwani ◽  
Rajnish Sahu ◽  
Lalit M. Tripathi ◽  
Larry A. Walker
Keyword(s):  
Cytochrome P450 ◽  
Human Erythrocytes ◽  
Toxic Effects

Two Mechanisms for Toxic Effects of Hydroxylamines in Human Erythrocytes: Involvement of Free Radicals and Risk of Potentiation

1998 ◽  
Vol 24 (3) ◽  
pp. 280-295 ◽  
Author(s):  
Chris T.A. Evelo ◽  
Anita A.M.G Spooren ◽  
Rob A.G. Bisschops ◽  
Leo G.M. Baars ◽  
John M. Neis
Keyword(s):  
Free Radicals ◽  
Human Erythrocytes ◽  
Toxic Effects

Ultrastructure of the effect of T-514 obtained from Karwinskia humboldtiana on assembly and integrity of yeast's peroxisomes

1991 ◽  
Vol 49 ◽  
pp. 136-137
Author(s):  
J. Sepulveda-Saavedra ◽  
I. Vander-Klei ◽  
M. Venhuis ◽  
Y. Piñeyro-Lopez
Keyword(s):  
Culture Conditions ◽  
Toxic Effects ◽  
Candida Boidinii ◽  
Central Mexico ◽  
Poisonous Plant ◽  
Biological Behaviour ◽  
Enzyme Content ◽  
Fat Deposits ◽  
Yeast Model

Karwinskia humboldtiana is a poisonous plant that grows in semi desertic areas in north and central México. It produces several substances with different toxic effects. One of them designated T-514 damages severely the lung, kidney and liver, producing in the hepatoeyte large intracellular fat deposits and necrosis. Preliminary observations demonstrated that three is a decrease in the amount of peroxisomes in the hepatocytes of experimentally intoxicated rats and monkeys. To study the effect exerted by the T-514 on peroxisomes, a yeast model was selected, thus, three species: Saccha romices cerevisiae, Ilansenula polymorpha and Candida boidinii were used, because there is information concerning their peroxisome's morphology, enzyme content, biological behaviour under different culture conditions and biogenesis.

Some Conditions Necessary for Pinocytosis

1968 ◽  
Vol 26 ◽  
pp. 142-143
Author(s):  
M. W. Brightman
Keyword(s):  
Smooth Muscle ◽  
Cell Membrane ◽  
Toxic Effects ◽  
Cytological Evidence ◽  
Cell Processes

The cytological evidence for pinocytosis is the focal infolding of the cell membrane to form surface pits that eventually pinch off and move into the cytoplasm. This activity, which can be inhibited by oxidative and glycolytic poisons, is performed only by cell processes that are at least 300A wide. However, the interpretation of such toxic effects becomes equivocal if the membrane invaginations do not normally lead to the formation of migratory vesicles, as in some endothelia and in smooth muscle. The present study is an attempt to set forth some conditions under which pinocytosis, as distinct from the mere inclusion of material in surface invaginations, can take place.

Elemental analysis of human erythrocytes

1989 ◽  
Vol 47 ◽  
pp. 242-243
Author(s):  
S. A. Livesey ◽  
A. A. del Campo ◽  
E. S. Griffey ◽  
D. Ohlmer ◽  
T. Schifani ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Elemental Analysis ◽  
Human Erythrocyte ◽  
Spectroscopic Analysis ◽  
Model System ◽  
Human Erythrocytes ◽  
List Type ◽  
Chemical Fixation ◽  
Ethanol Dehydration ◽  
Lowicryl K4m

The aim of this study is to compare methods of sample preparation for elemental analysis. The model system which is used is the human erythrocyte. Energy dispersive spectroscopic analysis has been previously reported for cryofixed and cryosectioned erythrocytes. Such work represents the reference point for this study. The use of plastic embedded samples for elemental analysis has also been documented. The work which is presented here is based on human erythrocytes which have been either chemically fixed and embedded or cryofixed and subsequently processed by a variety of techniques which culminated in plastic embedded samples.Heparinized and washed erythrocytes were prepared by the following methods for this study :(1). Chemical fixation in 4% paraformaldehyde/0.25% glutaraldehyde/0.2 M sucrose in 0.1 M Na cacodylate, pH 7.3 for 30 min, followed by ethanol dehydration, infiltration and embedding in Lowicryl K4M at -20° C.

Toxic effects of aerosol propellants on the heart

1973 ◽  
Vol 131 (1) ◽  
pp. 162-166 ◽  
Author(s):  
W. S. Harris
Keyword(s):  
Toxic Effects
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