scholarly journals Antidepressant prescribing in general practice – how long can this go on?

1991 ◽  
Vol 15 (5) ◽  
pp. 281-283 ◽  
Author(s):  
Michael P. Kerr
Keyword(s):  
General Practice ◽  
Maintenance Treatment ◽  
Antidepressant Medication ◽  
Unipolar Depression ◽  
Acute Illness ◽  
Duration Of Treatment ◽  
One Year ◽  
Prevention Of Relapse ◽  
Term Maintenance

Present guidelines for the prescribing of antidepressant medication, with particular reference to the duration of treatment, are unclear (BNF, 1989). Evidence suggests that continuation of treatment for at least six months is valuable in the prevention of relapse of the acute illness (Mindham et al, 1975). Other workers have demonstrated a prophylactic effect similar to lithium over a three year period in patients with unipolar depression. There is, however, a paucity of information about the benefits (or lack of benefits) of longer term maintenance treatment. This study focuses on a population of a type which has been previously studied elsewhere – of patients in general practice receiving long-term (greater than one year) antidepressant medication. The implications of this to the psychiatrist and general practice–psychiatry liaison are discussed.

Chemotherapy in malignant disease (February 13, 1970): correction

1970 ◽  
Vol 8 (13) ◽  
pp. 52.2-52
Keyword(s):  
Maintenance Treatment ◽  
Malignant Disease ◽  
Term Maintenance

Table 2 of this article stated wrongly that mercaptopurine and melphalan are unsuitable for long-term maintenance treatment. Both drugs are in fact suitable for this purpose.

scholarly journals Maintenance pharmacotherapy of unipolar depression

1999 ◽  
Vol 23 (6) ◽  
pp. 370-373 ◽  
Author(s):  
Som Forshall ◽  
David J. Nutt
Keyword(s):  
Prophylactic Treatment ◽  
Unipolar Depression ◽  
Term Treatment ◽  
Current Evidence ◽  
Full Remission ◽  
Long Term Treatment ◽  
Continuation Treatment ◽  
Term Maintenance ◽  
Review Current

Aims and methodsThe purpose of this paper is to review current evidence and opinion with regard to the long-term treatment of unipolar depression. The method employed was a Psychlit search using the search items long-term, maintenance, treatment and depression.ResultsThe search yielded 91 articles.Clinical implicationsUnipolar depression is frequently recurrent and sometimes a chronic illness. The paper identifies those at greatest risk of recurrence. It goes on to examine strategies to prevent relapse and for prophylactic treatment. It concludes that continuation treatment should be sustained at full dose for 4–6 months after full remission of symptoms. Where depression is highly recurrent the acute phase dose should be maintained in the long-term.

Help-Seeking in Depressed Out-patients Following Maintenance Therapy

1976 ◽  
Vol 129 (3) ◽  
pp. 252-260 ◽  
Author(s):  
Myrna M. Weissman ◽  
Stanislav V. Kasl
Keyword(s):  
Maintenance Therapy ◽  
Help Seeking ◽  
Maintenance Treatment ◽  
Suicide Attempts ◽  
Clinical Status ◽  
Subsequent Treatment ◽  
Access To Treatment ◽  
One Year

SummaryThis paper reports on the clinical status, help-seeking and subsequent treatment experiences of 150 women one year after they had completed out-patient maintenance treatment by amitriptyline and/or psychotherapy for a depressive episode.While the majority of patients were asymptomatic at follow-up, a substantial minority had a return of acute symptoms and 2 per cent made minor suicide attempts during the year. Admission to hospital was rare. However, only 30 per cent of the patients did not seek any treatment during the year and the majority received some psychotropic medication.The findings support the long-term need for prompt access to treatment by patients who have recovered from an acute depression.

scholarly journals Aripiprazole once-monthly 400 mg for long-term maintenance treatment of schizophrenia: a 52-week open-label study

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Timothy Peters-Strickland ◽  
Ross A Baker ◽  
Robert D McQuade ◽  
Na Jin ◽  
Anna Eramo ◽  
...  
Keyword(s):  
Maintenance Treatment ◽  
Open Label ◽  
Open Label Study ◽  
Label Study ◽  
Term Maintenance
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